Search Results - "Lingo, Joshuah"
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Ex vivo-expanded natural killer cells demonstrate robust proliferation in vivo in high-risk relapsed multiple myeloma patients
Published in Journal of immunotherapy (1997) (01-01-2015)“…Highly activated/expanded natural killer (NK) cells can be generated by stimulation with the human leukocyte antigen-deficient cell line K562, genetically…”
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Highly activated and expanded natural killer cells for multiple myeloma immunotherapy
Published in Haematologica (Roma) (01-09-2012)“…Patients with gene expression profiling-defined high-risk myeloma in relapse have poor outcomes with current therapies. We tested whether natural killer cells…”
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9-cis-Retinoic acid promotes cell adhesion through integrin dependent and independent mechanisms across immune lineages
Published in The Journal of nutritional biochemistry (01-05-2013)“…Retinoids are essential in the proper establishment and maintenance of immunity. Although retinoids are implicated in immune related processes, their role in…”
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All-trans-Retinoic Acid Induces Integrin-Independent B-Cell Adhesion to ADAM Disintegrin Domains
Published in Biochemistry (Easton) (15-04-2008)“…Cell adhesion is an integral aspect of immunity facilitating extravasation of immune cells during homing and activation. All-trans-Retinoic acid (t-RA)…”
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Differential ICAM3 Gene Expression Correlates with Susceptibility to Natural Killer Cell-Mediated Lysis in Multiple Myeloma
Published in Blood (03-12-2015)“…Introduction We previously reported on the generation of highly activated/expanded natural killer cells (ENKs) after coculture with K562 cells modified to…”
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Myeloma Can Modulate Expanded Natural Killer Cell Function Through Multiple Mechanisms
Published in Blood (16-11-2012)“…Abstract 4020 We previously showed that highly activated natural killer cells can be generated in large numbers from the peripheral blood mononuclear cells…”
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Impact Of Elotuzumab Therapy On Circulating and Ex Vivo Activated/Expanded Autologous Natural Killer (Auto-ENK) Cell Activity
Published in Blood (15-11-2013)“…CS1 is an ideal target for multiple myeloma (MM) therapy as it is highly expressed on MM while having a very limited expression profile in normal tissues. …”
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9‐cis‐Retinoic acid induces integrin‐independent immune cell adhesion
Published in The FASEB journal (01-04-2012)“…Abstract only Retinoids are essential in the proper establishment and maintenance of immunity. Although retinoids are implicated in immune related processes,…”
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Autologous Expanded Natural Killer Cells As a New Therapeutic Option for High-Risk Myeloma
Published in Blood (18-11-2011)“…Abstract 2918 Natural killer cells (NK) have the unique ability to kill target cells without priming. While their therapeutic potential against various…”
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Expanded Natural Killer (NK) Cells for Immunotherapy: Fresh and Made to Order
Published in Blood (16-11-2012)“…Abstract 1912 Remarkable increases in the dose and activity of NK cells can be achieved by co-culture with the HLA class I deficient cell line K562 that has…”
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Fresh Ex Vivo Expanded Natural Killer Cells Demonstrate Robust Proliferation in Vivo in High-Risk Relapsed Multiple Myeloma (MM) Patients
Published in Blood (16-11-2012)“…Abstract 579 Stimulation of NK cells with the HLA-deficient cell line K562 genetically modified to express 41BB-ligand and interleukin (IL) 15 allows for the…”
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