Search Results - "Lingjing, Xue"
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Neutrophil-mediated anticancer drug delivery for suppression of postoperative malignant glioma recurrence
Published in Nature nanotechnology (01-07-2017)“…Cell-mediated drug-delivery systems have received considerable attention for their enhanced therapeutic specificity and efficacy in cancer treatment…”
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2
Co-delivery of erlotinib and doxorubicin by pH-sensitive charge conversion nanocarrier for synergistic therapy
Published in Journal of controlled release (10-05-2016)“…Pretreatment of lung cancer cells with epidermal growth factor receptor (EGFR) inhibitor erlotinib has been recently reported that could dramatically synergize…”
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3
A Collaborative Assembly Strategy for Tumor-Targeted siRNA Delivery
Published in Journal of the American Chemical Society (13-05-2015)“…A novel “collaborative assembly” approach was reported for the synthesis of an siRNA delivery system via a combination of an electrostatically driven physical…”
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4
Reprogrammed siTNFα/neutrophil cytopharmaceuticals targeting inflamed joints for rheumatoid arthritis therapy
Published in Acta pharmaceutica Sinica. B (01-02-2023)“…Rheumatoid arthritis (RA) is an autoimmune disease characterized by severe synovial inflammation and cartilage damage. Despite great progress in RA therapy,…”
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5
Spatiotemporally Controlled T‐Cell Combination Therapy for Solid Tumor
Published in Advanced science (01-07-2024)“…Due to multidimensional complexity of solid tumor, development of rational T‐cell combinations and corresponding formulations is still challenging. Herein, a…”
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6
Transforming Weakness into Strength: Photothermal‐Therapy‐Induced Inflammation Enhanced Cytopharmaceutical Chemotherapy as a Combination Anticancer Treatment
Published in Advanced materials (Weinheim) (01-02-2019)“…A new synergistic treatment that combines photothermal therapy (PTT) and inflammation‐mediated active targeting (IMAT) chemotherapy based on…”
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7
Recognition, Intervention, and Monitoring of Neutrophils in Acute Ischemic Stroke
Published in Nano letters (10-07-2019)“…Neutrophils are implicated in numerous inflammatory diseases, and especially in acute ischemic stroke (AIS). The unchecked migration of neutrophils into…”
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8
Sequential Intra-Intercellular Nanoparticle Delivery System for Deep Tumor Penetration
Published in Angewandte Chemie International Edition (10-06-2014)“…To achieve deep tumor penetration of large‐sized nanoparticles (NPs), we have developed a reversible swelling–shrinking nanogel in response to pH variation for…”
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9
Reversal of multidrug resistance by co-delivery of paclitaxel and lonidamine using a TPGS and hyaluronic acid dual-functionalized liposome for cancer treatment
Published in Biomaterials (01-12-2015)“…Abstract Multidrug resistance (MDR) remains the primary issue in cancer therapy, which is characterized by the overexpressed P-glycoprotein (P-gp)-included…”
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10
Neoadjuvant Chemotherapy Based on Abraxane/Human Neutrophils Cytopharmaceuticals with Radiotherapy for Gastric Cancer
Published in Small (Weinheim an der Bergstrasse, Germany) (01-02-2019)“…Gastric cancer remains one of the most lethal cancers with high incidence and mortality worldwide. The majority of gastric cancer patients are those who have…”
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Combination of metabolic intervention and T cell therapy enhances solid tumor immunotherapy
Published in Science translational medicine (25-11-2020)“…Treatment of solid tumors with T cell therapy has yielded limited therapeutic benefits to date. Although T cell therapy in combination with proinflammatory…”
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12
Poly-β-cyclodextrin Supramolecular Nanoassembly with a pH-Sensitive Switch Removing Lysosomal Cholesterol Crystals for Antiatherosclerosis
Published in Nano letters (24-11-2021)“…Cholesterol crystals (CCs), originally accumulating in the lysosome of cholesterol-laden cells, can aggravate the progression of atherosclerosis…”
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13
An elastase-inhibiting, plaque-targeting and neutrophil-hitchhiking liposome against atherosclerosis
Published in Acta biomaterialia (01-01-2024)“…Neutrophil extracellular traps (NETs) play a crucial role in the formation of vulnerable plaques and the development of atherosclerosis. Alleviating the…”
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14
The Impaired Mechanism and Facilitated Therapies of Efferocytosis in Atherosclerosis
Published in Journal of cardiovascular pharmacology (01-09-2022)“…Cardiovascular disease is responsible for the largest number of deaths worldwide, and atherosclerosis is the primary cause. Apoptotic cell accumulation in…”
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15
Co-delivery of paclitaxel and anti-survivin siRNA via redox-sensitive oligopeptide liposomes for the synergistic treatment of breast cancer and metastasis
Published in International journal of pharmaceutics (30-08-2017)“…[Display omitted] The overexpression of survivin in breast cancer cells is an important factor of paclitaxel (PTX) resistance in breast cancer. To overcome PTX…”
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Anisamide-functionalized pH-responsive amphiphilic chitosan-based paclitaxel micelles for sigma-1 receptor targeted prostate cancer treatment
Published in Carbohydrate polymers (01-02-2020)“…[Display omitted] •Anisamide-conjugated N-octyl-N,O-maleoyl-O-phosphoryl chitosan (a-OPMPC) features with targeting ability and pH sensitivity.•a-OPMPC can…”
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An EPR-Independent extravasation Strategy: Deformable leukocytes as vehicles for improved solid tumor therapy
Published in Advanced drug delivery reviews (01-08-2022)“…[Display omitted] Effective delivery of therapeutic modality throughout the tumorous nidus plays a crucial role in successful solid tumor treatment. However,…”
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Nanocomposite hydrogel incorporating gold nanorods and paclitaxel-loaded chitosan micelles for combination photothermal–chemotherapy
Published in International journal of pharmaceutics (30-01-2016)“…[Display omitted] Development of combination photothermal–chemotherapy platform is of great interest for enhancing antitumor efficacy and inhibiting tumor…”
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New-generation cytopharmaceuticals with powerfully boosted extravasation for enhanced cancer therapy
Published in Journal of controlled release (01-07-2023)“…Effective extravasation of therapeutic agents into solid tumors still faces huge challenges. Since the doubted effectiveness of enhanced penetration and…”
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20
The Impaired Mechanism and Facilitated Therapies of Efferocytosis in Atherosclerosis
Published in Journal of cardiovascular pharmacology (06-06-2022)Get full text
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