Search Results - "Linggi, B"

ErbB receptors: new insights on mechanisms and biology by Linggi, Bryan, Carpenter, Graham

“…The ErbB family of four receptor tyrosine kinases occupies a central role in a wide variety of biological processes from neuronal development to breast cancer…”
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The ErbB-4 s80 intracellular domain is a constitutively active tyrosine kinase by Linggi, B, Cheng, Q C, Rao, A R, Carpenter, G

“…The ErbB-4 receptor tyrosine kinase homo- and heterodimerizes following heregulin binding, which provokes increased levels of tyrosine autophosphorylation…”
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P928 "Metabolism and Response to Stress" (MARS) gene signatures reveal heterogeneity in patients with Ulcerative Colitis and identify characteristics of patients with increased response to therapy by Linggi, B, Sangiorgi, B, Smith, M I, Teft, W, Jairath, V, Ma, C, Vande Casteele, N

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DOP35 Spatial transcriptomics reveals cellular niches associated with histological inflammation in postoperative Crohn’s Disease by Battat, R, Sangiorgi, B, Linggi, B, Gui, S, Torti, D, Smith, M I, Mehandru, S, Longman, R, Lukin, D J, Scherl, E J, Qin, L, Ma, C, Teft, W, Vande Casteele, N

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OP40 Transcriptomic signature of response to vedolizumab in patients with moderate-to-severe ulcerative colitis: Results from an international, multicentre, retrospective cohort study by Linggi, B, Salas, A, Veny, M, Borowski, K, Silverberg, M S, Milgrom, R, Stempak, J, Boland, B, Eckmann, L, Smith, M I, Parker, C E, Jairath, V, Teft, W, Vande Casteele, N

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Strategi Pembelajaran Model Blended Learning Solusi Keterbatasan Dosen by Pongantung, Henny, Elmiana B Linggi, Asrijal Bakri, Pricilia Tore

“…STIK Stella maris saat ini mengunakan metode pembelajaran                   konvensional dengan metode student center learning (SCL). Hal ini cukup memberatkan…”
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The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor suppressor in acute myeloid leukemia by Linggi, Bryan, Müller-Tidow, Carsten, van de Locht, Louis, Hu, Ming, Nip, John, Serve, Hubert, Berdel, Wolfgang E, van der Reijden, Bert, Quelle, Dawn E, Rowley, Janet D, Cleveland, John, Jansen, Joop H, Pandolfi, Pier Paolo, Hiebert, Scott W

“…The t(8;21) is one of the most frequent chromosomal translocations associated with acute leukemia. This translocation creates a fusion protein consisting of…”
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A Mechanism of Repression by Acute Myeloid Leukemia-1, the Target of Multiple Chromosomal Translocations in Acute Leukemia by Lutterbach, B, Westendorf, J J, Linggi, B, Isaac, S, Seto, E, Hiebert, S W

“…AML1 is one of the most frequently translocated genes in human leukemia. Here we demonstrate that acute myeloid leukemia-1 (AML-1) (Runx-1) represses…”
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ETO, a Target of t(8;21) in Acute Leukemia, Interacts with the N-CoR and mSin3 Corepressors by Lutterbach, Bart, Westendorf, Jennifer J., Linggi, Bryan, Patten, Andrea, Moniwa, Mariko, Davie, James R., Huynh, Khanh D., Bardwell, Vivian J., Lavinsky, Robert M., Rosenfeld, Michael G., Glass, Christopher, Seto, Edward, Hiebert, Scott W.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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298 Identification of plasmacytoid dendritic cell induced proteins as potential biomarkers for jnj-56022473 by Monaghan, K, Linggi, B, Ng, M, Tai, TY, Jordan, J, Cesaroni, M, Benson, J, Tarlinton, C, Morand, E, Hoi, A, Wilson, N

“…Background and aimsPlasmacytoid dendritic cells (pDC) are potent producers of IFNα, we investigated what additional soluble factors are produced by pDCs and…”
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Expression of the AML-1 oncogene shortens the G(1) phase of the cell cycle by Strom, D K, Nip, J, Westendorf, J J, Linggi, B, Lutterbach, B, Downing, J R, Lenny, N, Hiebert, S W

“…The AML-1-encoded transcription factor, AML-1B, regulates numerous hematopoietic-specific genes. Inappropriate expression of AML-1-family proteins is oncogenic…”
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Specific Protein Redirection as a Transcriptional Therapy Approach for t(8;21) Leukemia by Steffen, Björn, Serve, Hubert, Berdel, Wolfgang E., Agrawal, Shuchi, Linggi, Bryan, Büchner, Thomas, Hiebert, Scott W., Müller-Tidow, Carsten

“…Important progress has been achieved in the knowledge about the pathogenesis of cancer. However, despite these advances, the therapeutic strategies are still…”
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Mechanisms of transcriptional repression by the t(8;21)-, t(12;21)-, and inv(16)-encoded fusion proteins by HIEBERT, Scott W, LUTTERBACH, Bart, DURST, Kristie, LILIN WANG, LINGGI, Bryan, WU, Steve, WOOD, Lauren, AMANN, Joseph, KING, Dana, YUE HOU

“…AML-1 is one of the most frequently translocated genes in human leukemia. AML-1 binds DNA and activates or represses transcription, while the chromosomal…”
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Translating the histone code into leukemia by Linggi, Bryan E., Brandt, Stephen J., Sun, Zu-Wen, Hiebert, Scott W.

“…The “histone code” is comprised of the covalent modifications of histone tails that function to regulate gene transcription. The post‐translational…”
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The t(8; 21) fusion protein, AML1-ETO, specifically represses the transcription of the p14 super(ARF) tumor suppressor in acute myeloid leukemia by Linggi, B, Mueller-Tidow, C, Van De Locht, L, Hu, Ming, Nip, J, Serve, H, Berdel, W E, Van Der Reijden, B, Quelle, DE, Rowley, J D, Cleveland, J, Jansen, J H, Pandolfi, P P, Hiebert, S W

“…The t(8; 21) is one of the most frequent chromosomal translocations associated with acute leukemia. This translocation creates a fusion protein consisting of…”
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Expression of the AML-1 Oncogene Shortens the G sub(1) Phase of the Cell CycLe by Strom, D K, Nip, J, Westendorf, J J, Linggi, B, Lutterbach, B, Downing, J R, Lenny, N, Hiebert, S W

“…The AML-1-encoded transcription factor, AML-1B, regulates numerous hematopoietic-specific genes. Inappropriate expression of AML-1-family proteins is oncogenic…”
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