Search Results - "Ling, Zao Dung"

Differentiation of Mesencephalic Progenitor Cells into Dopaminergic Neurons by Cytokines by Ling, Zao Dung, Potter, Elizabeth D., Lipton, Jack W., Carvey, Paul M.

“…Rat progenitor cells from the germinal region of the fetal mesencephalon were isolated and expanded in media containing the mitogen epidermal growth factor…”
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Intravenous immunoglobulin induces interferon-γ and interleukin-6 in vivo by ZAO-DUNG LING, EUNICE YEOH, WEBB, B. T, FARRELL, K, DOUCETTE, J, MATHESON, D. S

“…Immunoglobulin is known to be an immunomodulator. It can induce protein mediators from mononuclear cells, particularly monocytes in vitro. Intravenous…”
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Comparison of the neurotoxicity of dihydroxyphenylalanine stereoisomers in cultured dopamine neurons by Ling, Z D, Pieri, S C, Carvey, P M

“…Oxidant stress resulting from excess dopamine (DA) may contribute to the development and progression of Parkinson's disease (PD). Free radicals resulting from…”
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Both the antioxidant and D3 agonist actions of pramipexole mediate its neuroprotective actions in mesencephalic cultures by Ling, Z D, Robie, H C, Tong, C W, Carvey, P M

“…Pramipexole (PPX) is a full intrinsic activity, direct-acting dopamine (DA) agonist possessing 7-fold higher affinity for D3 than for D2 receptors. It also is…”
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Striatal trophic activity is reduced in the aged rat brain by Ling, Zao Dung, Collier, Timothy J., Sortwell, Caryl E., Lipton, Jack W., Vu, Toan Q., Robie, Heather C., Carvey, Paul M.

“…Our previous studies demonstrated that the survival of a mesencephalic graft was reduced in aged animals suggesting an age-related decline in target-derived…”
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Dopamine D3 receptors : Relevance for the drug treatment of Parkinson's disease by LEVANT, B, ZAO DUNG LING, CARVEY, P. M

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Production of factors with B-cell growth and differentiation activities by peripheral blood mononuclear cells from patients with hypogammaglobulinemia by Matheson, David S., Webb, Barbara T., Green, Bridget J., Hart, Liza J., Bowen, Thomas J., Junker, Anne K., Pabst, Henry, Tingle, Aubrey J., Ling, Zao-Dung

“…Background: The maturation of normal B lymphocytes proceeds through a growth phase and a differentiation phase. These two phases appear to be under the…”
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Catechol-O-methyltransferase inhibition attenuates levodopa toxicity in mesencephalic dopamine neurons by Storch, A, Blessing, H, Bareiss, M, Jankowski, S, Ling, Z D, Carvey, P, Schwarz, J

“…Inhibition of catechol-O-methyltransferase (COMT; EC 2.1.1.6) is a new therapeutic strategy in the treatment of Parkinson's disease. However, nothing is known…”
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Partial purification of a pramipexole-induced trophic activity directed at dopamine neurons in ventral mesencephalic cultures by Ling, Zao Dung, Tong, Chong Wai, Carvey, Paul M

“…We previously demonstrated that media conditioned by exposure to ventral mesencephalic (VM) cultures in the presence of pramipexole (PPX) and other drugs with…”
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In utero bacterial endotoxin exposure causes loss of tyrosine hydroxylase neurons in the postnatal rat midbrain by Ling, ZaoDung, Gayle, Dave A., Ma, Shang Yong, Lipton, Jack W., Tong, Chong Wai, Hong, Jau-Shyong, Carvey, Paul M.

“…We investigated whether in utero exposure to the Gram(−) bacteriotoxin lipopolysaccharide (LPS) induces dopamine (DA) neuron loss in rats. The proinflammatory…”
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Tumor Necrosis Factor α Is Toxic to Embryonic Mesencephalic Dopamine Neurons by McGuire, Susan O, Ling, Zao Dung, Lipton, Jack W, Sortwell, Caryl E, Collier, Timothy J, Carvey, Paul M

“…Levels of the proinflammatory cytokine tumor necrosis factor α (TNFα) are increased in postmortem brain and cerebral spinal fluid from patients with…”
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Aggregated immunoglobulin and Fc fragment of IgG induce IL-6 release from human monocytes by Ling, Z D, Ziltener, H J, Webb, B T, Matheson, D S

“…The Fc fragment of immunoglobulin (Ig) has been shown to play an important role in the regulation of humoral immunity, cellular immunity, lymphocyte and…”
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Striatal trophic factor activity in aging monkeys with unilateral MPTP-induced parkinsonism by Collier, Timothy J., Dung Ling, Zao, Carvey, Paul M., Fletcher-Turner, Anita, Yurek, David M., Sladek, John R., Kordower, Jeffrey H.

“…Striatal trophic activity was assessed in female rhesus monkeys of advancing age rendered hemiparkinsonian by unilateral intracarotid administration of MPTP…”
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Regulation of Fc-induced IL-6 from human peripheral blood mononuclear cells by Ling, Z D, Webb, B T, Yeoh, E, Matheson, D S

“…Previous experiments demonstrated that aggregated immunoglobulin and the Fc fragment of human IgG can induce interleukin-6 (IL-6) secretion from peripheral…”
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Cytokine-induced conversion of mesencephalic-derived progenitor cells into dopamine neurons by Potter, E D, Ling, Z D, Carvey, P M

“…We have previously shown that a combination of the cytokines interleukin (IL)-1, IL-11, leukemia inhibitory factor (LIF), and glial cell line-derived…”
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Particle concentration fluorescence immunoassay for measuring interleukin-6 receptor numbers by Ling, Z D, Gillis, S, Hart, L J, Matheson, D S

“…Analysis of the number of receptors per cell and the affinity of the ligand/receptor interaction has provided considerable insight into the functioning of…”
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GFAP knockout mice have increased levels of GDNF that protect striatal neurons from metabolic and excitotoxic insults by Hanbury, Rose, Ling, Zao Dung, Wuu, Joanne, Kordower, Jeffrey H.

“…In response to injury and degeneration, astrocytes hypertrophy, extend processes, and increase production of glial fibrillary acidic protein (GFAP), an…”
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Lipopolysaccharide (LPS)-induced dopamine cell loss in culture: roles of tumor necrosis factor-α, interleukin-1β, and nitric oxide by Gayle, Dave A, Ling, ZaoDung, Tong, ChongWai, Landers, Teresa, Lipton, Jack W, Carvey, Paul M

“…Parkinson’s disease (PD) is a neurodegenerative disorder characterized by the loss of dopamine (DA) neurons of the substantia nigra pars compacta (SNc)…”
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Tumor necrosis factor a is toxic to embryonic mesencephalic dopamine neurons by MCGUIRE, Susan O, ZAO DUNG LING, LIPTON, Jack W, SORTWELL, Caryl E, COLLIER, Timothy J, CARVEY, Paul M

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Dopamine D3 Receptors: Relevance for the Drug Treatment of Parkinson??s Disease by Levant, Beth, Ling, Zao Dung, Carvey, Paul M.

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