Search Results - "Ling, Yiwei"
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Histopathological characteristics and artificial intelligence for predicting tumor mutational burden-high colorectal cancer
Published in Journal of gastroenterology (01-06-2021)“…Background Tumor mutational burden-high (TMB-H), which is detected with gene panel testing, is a promising biomarker for immune checkpoint inhibitors (ICIs) in…”
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2
Unveiling microbiome profiles in human inner body fluids and tumor tissues with pancreatic or biliary tract cancer
Published in Scientific reports (24-05-2022)“…With the discovery of bacterial symbiosis in the tissues of various cancers, the study of the tumor microbiome is attracting a great deal of attention…”
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3
Development of a lip vermilion epithelium reconstruction model using keratinocytes from skin and oral mucosa
Published in Histochemistry and cell biology (01-10-2023)“…Lip vermilion is unique and can be distinguished from the adjacent skin and oral mucosa. However, because of the lack of appropriate evaluation tools, skin…”
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4
Insights into predicting small molecule retention times in liquid chromatography using deep learning
Published in Journal of cheminformatics (07-10-2024)“…In untargeted metabolomics, structures of small molecules are annotated using liquid chromatography-mass spectrometry by leveraging information from the…”
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BRAF V600E and SRC mutations as molecular markers for predicting prognosis and conversion surgery in Stage IV colorectal cancer
Published in Scientific reports (21-02-2019)“…Comprehensive genomic sequencing (CGS) enables us to detect numerous genetic alterations in a single assay. We aimed to identify molecular markers for…”
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Escherichia coli‐derived outer‐membrane vesicles induce immune activation and progression of cirrhosis in mice and humans
Published in Liver international (01-05-2023)“…Background and Aims Decompensated cirrhosis with fibrosis progression causes portal hypertension followed by an oedematous intestinal tract. These conditions…”
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Recent trends and perspectives in reconstruction and regeneration of intra/extra-oral wounds using tissue-engineered oral mucosa equivalents
Published in The Japanese dental science review (01-12-2023)“…Many conditions, including cancer, trauma, and congenital anomalies, can damage the oral mucosa. Multiple cultures of oral mucosal cells have been used for…”
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8
Loss of Atg2b and Gskip Impairs the Maintenance of the Hematopoietic Stem Cell Pool Size
Published in Molecular and cellular biology (01-01-2022)“…A germ line copy number duplication of chromosome 14q32, which contains ATG2B and GSKIP, was identified in families with myeloproliferative neoplasm (MPN)…”
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AldB controls persister formation in Escherichia coli depending on environmental stress
Published in Microbiology and immunology (01-05-2018)“…ABSTRACT Persisters are multidrug‐tolerant cells that are present within antibiotic‐sensitive populations. Persister formation is not induced by genetic…”
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10
Identification of TRA‐1‐60‐positive cells as a potent refractory population in follicular lymphomas
Published in Cancer science (01-01-2019)“…Despite receiving rituximab‐combined chemotherapy, follicular lymphoma (FL) patients often suffer tumor recurrence and understand that the cause of relapse in…”
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Plasma Sphingosine-1-Phosphate Levels Are Associated with Progression of Estrogen Receptor-Positive Breast Cancer
Published in International journal of molecular sciences (13-12-2021)“…Although numerous experiments revealed an essential role of a lipid mediator, sphingosine-1-phosphate (S1P), in breast cancer (BC) progression, the clinical…”
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12
Actionable gene-based classification toward precision medicine in gastric cancer
Published in Genome medicine (31-10-2017)“…Intertumoral heterogeneity represents a significant hurdle to identifying optimized targeted therapies in gastric cancer (GC). To realize precision medicine…”
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Characteristics linked to the reduction of stigma towards schizophrenia: a pre-and-post study of parents of adolescents attending an educational program
Published in BMC public health (18-03-2014)“…The stigma of schizophrenia constitutes a major barrier to early detection and treatment of this illness. Anti-stigma education has been welcomed to reduce…”
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Profiling of host genetic alterations and intra-tumor microbiomes in colorectal cancer
Published in Computational and structural biotechnology journal (01-01-2021)“…[Display omitted] Some bacteria are symbiotic in tumor tissues, and metabolites of several bacterial species have been found to cause DNA damage. However, to…”
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The Human Gut Microbiome is Structured to Optimize Molecular Interaction Networks
Published in Computational and structural biotechnology journal (01-01-2019)“…Microbiome studies estimate the functions of bacterial flora in situ on the basis of species composition and gene function; however, estimation of interspecies…”
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Genomic landscape of colorectal cancer in Japan: clinical implications of comprehensive genomic sequencing for precision medicine
Published in Genome medicine (22-12-2016)“…Comprehensive genomic sequencing (CGS) has the potential to revolutionize precision medicine for cancer patients across the globe. However, to date large-scale…”
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17
Copy number alteration is an independent prognostic biomarker in triple-negative breast cancer patients
Published in Breast cancer (Tokyo, Japan) (01-07-2023)“…Background Next-generation sequencing (NGS) has enabled comprehensive genomic profiling to identify gene alterations that play important roles in cancer…”
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Verification of the Japanese staging system for rectal cancer, focusing on differences with the TNM classification
Published in Surgery today (Tokyo, Japan) (01-11-2020)“…Purpose The 9th Japanese Classification of Colorectal Cancer (9th JSCCR) has two main differences from the TNM classification (8th AJCC): first, main or…”
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NKp44-based chimeric antigen receptor effectively redirects primary T cells against synovial sarcoma
Published in Translational oncology (01-11-2022)“…•CAR-based cell therapies may be an option for treating synovial sarcomas.•NKp44 ligands were found to be most prevalent in synovial sarcoma cells.•NKp44-based…”
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Genome-Wide Target Analyses of Otx2 Homeoprotein in Postnatal Cortex
Published in Frontiers in neuroscience (31-05-2017)“…Juvenile brain has a unique time window, or critical period, in which neuronal circuits are remodeled by experience. Mounting evidence indicates the importance…”
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