Search Results - "Ling, Xinyu"

Cas9 exo-endonuclease eliminates chromosomal translocations during genome editing by Yin, Jianhang, Lu, Rusen, Xin, Changchang, Wang, Yuhong, Ling, Xinyu, Li, Dong, Zhang, Weiwei, Liu, Mengzhu, Xie, Wutao, Kong, Lingyun, Si, Wen, Wei, Ping, Xiao, Bingbing, Lee, Hsiang-Ying, Liu, Tao, Hu, Jiazhi

“…The mechanism underlying unwanted structural variations induced by CRISPR-Cas9 remains poorly understood, and no effective strategy is available to inhibit the…”
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Comprehensive analysis illustrating the role of PANoptosis-related genes in lung cancer based on bioinformatic algorithms and experiments by Wei, Shiyou, Chen, Zhigang, Ling, Xinyu, Zhang, Wentian, Jiang, Lei

“…Recently, PANoptosis has aroused the interest of researchers for its role in cancers. However, the studies that investigated PANoptosis in lung cancer are…”
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Elk1 enhances inflammatory cell infiltration and exacerbates acute lung injury/acute respiratory distress syndrome by suppressing Fcgr2b transcription by Wei, Shiyou, Ling, Dandan, Zhong, Jingui, Chang, Rui, Ling, Xinyu, Chen, Zhigang, Duan, Ruowang

“…Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are associated with significant mortality rates. The role of Fcgr2b in the pathogenesis…”
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Innovative CRISPR Screening Promotes Drug Target Identification by Ling, Xinyu, Liu, Tao

“…Jingxin Wang and co-workers provide an elegant selection platform to identify the targets of a nonproliferative drug by linking transcription activation to a…”
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Irf7 regulates the expression of Srg3 and ferroptosis axis aggravated sepsis-induced acute lung injury by Ling, Xinyu, Wei, Shiyou, Ling, Dandan, Cao, Siqi, Chang, Rui, Wang, Qiuyun, Yuan, Zhize

“…Abstract Objective To investigate the mechanism of action of Srg3 in acute lung injury caused by sepsis. Methods First, a sepsis-induced acute lung injury rat…”
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Study on Shrinkage in Alkali-Activated Slag-Fly Ash Cementitious Materials by Cui, Peng, Wan, Yuanyuan, Shao, Xuejun, Ling, Xinyu, Zhao, Long, Gong, Yongfan, Zhu, Chenhui

“…Traditional silicate cement materials produce a large amount of CO during production, making it urgent to seek alternatives. Alkali-activated slag cement is a…”
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The complete chloroplast genome sequence of Chrysojasminum subhumile and its phylogenetic position within Oleaceae by Ling, Xinyu, Liao, Rui, Zhu, Xingfu

“…We assembled and characterized the complete chloroplast genome sequence of Chrysojasminum subhumile (W.W.Sm.) Banfi & Galasso 2014, a valuable horticultural…”
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Efficient generation of locus-specific human CAR-T cells with CRISPR/cCas12a by Ling, Xinyu, Chang, Liying, Chen, Heqi, Liu, Tao

“…We recently developed a system to create human chimeric antigen receptor (CAR)-T cells using conjugated Cas12a (cCas12a) in which Cas12a is covalently linked…”
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CHADS2 and CHA2DS2-VASc scoring systems for predicting atrial fibrillation following cardiac valve surgery by Yin, Liang, Ling, Xinyu, Zhang, Yufeng, Shen, Hua, Min, Jie, Xi, Wang, Wang, Jing, Wang, Zhinong

“…Clinical use of CHADS2 and CHA2DS2-VASc scoring systems for predicting AF following cardiac surgery have been reported in previous studies and demonstrated…”
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Site-specific protein modification by genetic encoded disulfide compatible thiols by Ling, Xinyu, Chen, Heqi, Zheng, Wei, Chang, Liying, Wang, Yong, Liu, Tao

“…Cysteine engineering is challenging for recombinant expression of disulfide containing proteins, such as antibody fragment. Here we used genetic code expansion…”
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Glycemic control is associated with atrial structural remodeling in patients with type 2 diabetes by Wang, Qing, Wang, Jing, Wang, Pei, Wang, Liaoyuan, Jia, Lanting, Ling, Xinyu, Xi, Wang, Min, Jie, Shen, Hua, Xiao, Jian, Yuan, Jinxiang, Wang, Zhinong

“…Diabetes mellitus (DM) has been demonstrated to be a strong risk factor for development and perpetuation of atrial fibrillation (AF). However, how DM and…”
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Surgical treatment of cardiac tumors: a 5-year experience from a single cardiac center by Yin, Liang, He, Dengke, Shen, Hua, Ling, Xinyu, Li, Wei, Xue, Qian, Wang, Zhinong

“…Cardiac tumors are rare but manifested with various clinical presentations and often cause unexpected symptoms or sudden death. The objective is to review the…”
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Evaluation of COC183B2 antibody targeting ovarian cancer by near-infrared fluorescence imaging by Zhang, Chen, Ling, Xinyu, Guo, Yanxiu, Yuan, Cunzhong, Cheng, Hongyan, Ye, Xue, Ma, Ruiqiong, Zhang, Yinli, Li, Yi, Chang, Xiaohong, Kong, Beihua, Liu, Tao, Cui, Heng

“…To evaluate the imaging potential of a novel near-infrared (NIR) probe conjugated to COC183B2 monoclonal antibodies (MAb) in ovarian cancer (OC). The…”
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Coronary Artery Bypass Grafting Versus Combined Coronary Artery Bypass Grafting and Mitral Valve Repair in Treating Ischaemic Mitral Regurgitation: A Meta-analysis by Yin, Liang, PhD, Wang, Zhinong, MD, Shen, Hua, PhD, Min, Jie, PhD, Ling, Xinyu, PhD, Xi, Wang, PhD

“…Background Ischaemic mitral regurgitation (IMR) is commonly manifested after coronary artery disease, but it is still controversial as to whether coronary…”
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Improving the efficiency of CRISPR-Cas12a-based genome editing with site-specific covalent Cas12a-crRNA conjugates by Ling, Xinyu, Chang, Liying, Chen, Heqi, Gao, Xiaoqin, Yin, Jianhang, Zuo, Yi, Huang, Yujia, Zhang, Bo, Hu, Jiazhi, Liu, Tao

“…The CRISPR-Cas12a system shows unique features compared with widely used Cas9, making it an attractive and potentially more precise alternative. However, the…”
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Engineering Anti‐CRISPR Proteins to Create CRISPR‐Cas Protein Switches for Activatable Genome Editing and Viral Protease Detection by Kang, Wenyuan, Xiao, Fei, Zhu, Xi, Ling, Xinyu, Xie, Shiyi, Li, Ruimiao, Yu, Peihang, Cao, Linxin, Lei, Chunyang, Qiu, Ye, Liu, Tao, Nie, Zhou

“…Proteins capable of switching between distinct active states in response to biochemical cues are ideal for sensing and controlling biological processes…”
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Optical Control of a CRISPR/Cas9 System for Gene Editing by Using Photolabile crRNA by Zhang, Yu, Ling, Xinyu, Su, Xiaoxuan, Zhang, Shilin, Wang, Jing, Zhang, Pingjing, Feng, Wenjian, Zhu, York Yuanyuan, Liu, Tao, Tang, Xinjing

“…Currently CRISPR/Cas9 is a widely used efficient tool for gene editing. Precise control over the CRISPR/Cas9 system with high temporal and spatial resolution…”
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Rational design of minimum CRISPR guide RNA by site-specific Cas9-RNA conjugation by Ling, Xinyu, Gao, Xiaoqin, Chang, Liying, Chen, Heqi, Shi, Xiaomeng, Liu, Tao

“…The CRISPR-Cas9 system enables facile and efficient genome engineering in living cells and organisms. We report a Cas9-RNA conjugation strategy to afford…”
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Tracking endogenous proteins based on RNA editing-mediated genetic code expansion by Hao, Min, Ling, Xinyu, Sun, Yi, Wang, Xue, Li, Wenzhe, Chang, Liying, Zeng, Zhiying, Shi, Xiaomeng, Niu, Mengxiao, Chen, Liangyi, Liu, Tao

“…Protein labeling approaches are important to study proteins in living cells, and genome editing tools make it possible to tag endogenous proteins to address…”
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Polyvalent mRNA vaccination elicited potent immune response to monkeypox virus surface antigens by Fang, Zhenhao, Monteiro, Valter S., Renauer, Paul A., Shang, Xingbo, Suzuki, Kazushi, Ling, Xinyu, Bai, Meizhu, Xiang, Yan, Levchenko, Andre, Booth, Carmen J., Lucas, Carolina, Chen, Sidi

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