Search Results - "Ling, P R"

Circulating ghrelin concentrations are lowered by intravenous glucose or hyperinsulinemic euglycemic conditions in rodents by McCowen, KC, Maykel, JA, Bistrian, BR, Ling, PR

“…Ghrelin is a peptide secreted mainly by gastric parietal cells that may play a role in appetite regulation. Circulating ghrelin is abruptly lowered by food…”
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Mechanisms of host wasting induced by administration of cytokines in rats by Ling, P R, Schwartz, J H, Bistrian, B R

“…This study determined the effects of chronic administration of the two principal proximate cytokines, interleukin-1 (IL-1) and tumor necrosis factor (TNF), on…”
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Inflammatory mediators in patients receiving long-term home parenteral nutrition by LING, Pei-Ra, KHAODHIAR, Lalita, BISTRIAN, Bruce R, KEANE-ELLISON, Mary, THIBAULT, Ann, TAWA, Nicholas

“…This study was designed to examine circulating and urine cytokine levels in patients receiving long-term home total parenteral nutrition (TPN) support. Twelve…”
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Metabolic changes in rats during a continuous infusion of recombinant interleukin-1 by Ling, P R, Schwartz, J H, Jeevanandam, M, Gauldie, J, Bistrian, B R

“…The effects of recombinant interleukin-1 (IL-1), given as a continuous infusion for 6 days, on host responses were determined in rats. The development of…”
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Conditionally essential fatty acid deficiencies in end-stage liver disease by Burke, Peter A, Ling, P.R, Forse, R.A, Bistrian, Bruce R

“…Patients with end-stage liver disease (ESLD) manifest a wide variety of functional abnormalities that lead eventually to their death. Such patients also often…”
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Cholecystokinin (CCK) secretion in patients with severe short bowel syndrome (SSBS) by LING, Pei-Ra, SHEIKH, Mohammed, BOYCE, Patricia, KEANE-ELLISON, Mary, THIBAULT, Ann, BURKE, Peter, FREEDMAN, Steven, BISTRIAN, Bruce R

“…This study examined the effects of a liquid meal on cholecystokinin (CCK) secretion in patients with severe short bowel syndrome (SSBS) receiving home total…”
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Role of Arachidonic Acid in the Regulation of the Inflammatory Response in TNF-α-treated Rats by Ling, Pei-Ra, Boyce, Patricia, Bistrian, Bruce R.

“…Background: This study examined whether adding arachidonic acid (AA) to a fish oil diet would alter certain of the anti-inflammatory effects of fish oil in…”
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Differential effects of interleukin-1 receptor antagonist in cytokine- and endotoxin-treated rats by Ling, P R, Istfan, N W, Colon, E, Bistrian, B R

“…Previous studies have demonstrated that the administration of the cytokines, interleukin-1 (IL-1) and tumor necrosis factor (TNF)(20 micrograms/kg) to rats in…”
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Insulin-like growth factor-I improves glucose utilization in tumor necrosis factor—treated rats under hyperinsulinemic-euglycemic conditions by Ling, Pei Ra, Sierra, Pilar, Qu, Zhensheng, Bistrian, Bruce R.

“…The purpose of this study was to determine the effects of insulin-like growth factor-I (IGF-I) on glucose metabolism in normal and tumor necrosis factor…”
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Effects of dietary protein and tumor necrosis factor on components of the insulin-like growth factor-I pathway in the colon and small intestine in protein-depleted rats by Qu, Zhensheng, Ling, Pei-Ra, Chow, Jesse C., Smith, Robert J., Bistrian, Bruce R.

“…Intestinal cell growth is markedly affected by nutrient intake and the presence of cytokines. Since insulin-like growth factor-I (IGF-I) is an important…”
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Determinants of plasma concentrations of insulin-like growth factor-I and albumin and their hepatic mRNAs: The role of dietary protein content and tumor necrosis factor in malnourished rats by Qu, Zhensheng, Ling, Pei-Ra, Chow, Jesse C., Burke, Peter A., Smith, Robert J., Bistrian, Bruce R.

“…Protein restriction decreases plasma concentrations of albumin and insulin-like growth factor-I (IGF-I) by reducing their hepatic mRNA levels, whereas protein…”
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Effect of fetal growth on maternal protein metabolism in postabsorptive rat by Ling, P R, Bistrian, B R, Blackburn, G L, Istfan, N

“…Rates of protein synthesis were measured in whole fetuses and maternal tissues at 17 and 20 days of gestation in postabsorptive rats using continuous infusion…”
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Tissue-specific effects of chronic dietary protein restriction and gastrostomy on the insulin-like growth factor-I pathway in the liver and colon of adult rats by Qu, Zhensheng, Chow, Jesse C., Ling, Pei-Ra, Ziegler, Thomas R., Bistrian, Bruce R., Smith, Robert J.

“…Dietary protein restriction decreases plasma concentrations of insulin-like growth factor-I (IGF-I) and reduces IGF-I mRNA levels in the liver. In addition to…”
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Enhancement of tumor proteolysis by TNF-alpha: correlation of in vivo isotope estimates with growth by Istfan, N W, Ling, P R, Blackburn, G L, Bistrian, B R

“…To evaluate the accuracy of in vivo estimates of protein synthesis and breakdown, measurements of plasma and tissue leucine kinetics were made in rat tumor…”
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Endotoxin-induced inhibition of growth hormone receptor signaling in rat liver in vivo by Mao, Y, Ling, P R, Fitzgibbons, T P, McCowen, K C, Frick, G P, Bistrian, B R, Smith, R J

“…The bacterial lipopolysaccharide endotoxin induces a catabolic response characterized by resistance to multiple anabolic hormones. The objective of this study…”
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Systemic exchangeability of enteral leucine: relationship to plasma flux by Istfan, N.W, Ling, P.R, Bistrian, B.R, Blackburn, G.L

“…The exchangeability of enterally infused leucine within the systemic compartment was estimated in fasted and fed rats using L-[1-14C]leucine as a tracer. The…”
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Effects of Different Lipid Sources in Total Parenteral Nutrition on Whole Body Protein Kinetics and Tumor Growth by Mendez, Beatrice, Pei Ra Ling, Istfan, Nawfal W., Babayan, Vigen K., Bistrian, Bruce R.

“…This study examined the short-term effects of three total parenteral nutrition solutions, each containing a different lipid source, on host and tumor protein…”
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Growth hormone stimulates tyrosine phosphorylation of JAK2 and STAT5, but not insulin receptor substrate-1 or SHC proteins in liver and skeletal muscle of normal rats in vivo by Chow, J C, Ling, P R, Qu, Z, Laviola, L, Ciccarone, A, Bistrian, B R, Smith, R J

“…GH has been shown to stimulate tyrosine phosphorylation of JAK2, several STAT proteins, insulin receptor substrate-1 (IRS-1), and SHC proteins in cultured…”
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Immunologic Effects of Acute Hyperglycemia in Nondiabetic Rats by Kwoun, Moon O., Pei Ra Ling, Lydon, Erin, Imrich, Amy, Zhensheng Qu, Palombo, John, Bistrian, Bruce R.

“…Background: This study was designed to determine the consequences of acute hyperglycemia on the immune function of peripheral neutrophils, peritoneal…”
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Sustained endotoxemia leads to marked down-regulation of early steps in the insulin-signaling cascade by McCowen, Karen C, Ling, Pei Ra, Ciccarone, Annamaria, Mao, Yilei, Chow, Jesse C, Bistrian, Bruce R, Smith, Robert J

“…OBJECTIVESTo determine the effects of sustained, 3-day endotoxin infusion on early steps of the insulin-signaling pathway in rat liver and skeletal muscle in…”
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