Search Results - "Ling, N. R."

Preclinical studies with the anti-CD19-saporin immunotoxin BU12-SAPORIN for the treatment of human-B-cell tumours by FLAVELL, D. J, FLAVELL, S. U, BOEHM, D. A, EMERY, L, NOSS, A, LING, N. R, RICHARDSON, P. R, HARDIE, D, WRIGHT, D. H

“…The immunotoxin BU12-SAPORIN was constructed by covalently coupling the single-chain ribosome-inactivating protein saporin to the anti-CD19 monoclonal antibody…”
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Immunoglobulin production by cultured human lymphocytes by Ling, Noel R

“…The synthesis and secretion of immunoglobulin induced in cultured B-lineage cells is of interest for several reasons: (i) analysing the B-cell repertoire, (ii)…”
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Human major histocompatibility complex class II invariant chain is expressed on the cell surface by WRAIGHT, C. J, VAN ENDERT, P, MÖLLER, P, LIPP, J, LING, N. R, MACLENNAN, I. C. M, KOCH, N, MOLDENHAUER, G

“…Class II major histocompatibility complex antigens are intracellularly associated with a nonpolymorphic polypeptide referred to as the invariant chain. Before…”
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Origin and properties of soluble CD21 (CR2) in human blood by LING, N. R, HARDIE, D. L, JOHNSON, G. D, MACLENNAN, I. C. M

“…By analysis with a panel of CD21 MoAbs it is shown that a large part of the soluble CD21 in human blood plasma is of the long isoform (CD21L), as judged by…”
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Production of immunoglobulins by human sIgD+ and sIgD− human blood B lymphocytes in response to stimulation with activated T cells and agonistic antibodies; effect of IL‐10, IL‐2 and mode of activation of T cells by LING, N. R., BROWN, B., HARDIE, D.

“…SUMMARY Production of IgM, IgG and IgA was induced from human blood B lymphocytes by culturing with a CD40 MoAb and IL‐2 for 9 days. Replacement of IL‐2 by…”
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Working in a danger zone: A qualitative study of Taiwanese nurses' work experiences in a negative pressure isolation ward by Chen, Shu-Ling, RN, PhD, Chen, Kuei-Ling, RN, MSN, Lee, Li-Hung, RN, PhD, Yang, Cheng-I., RN, PhD

“…Highlights • Nurses' work experience in a negative pressure isolation ward may be characterized by the complexity of patient care, lack of equipment, and…”
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Pitfalls in the measurement of soluble forms of cell surface receptors by LING, N. R.

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A phenotypic study of cells from Burkitt lymphoma and EBV-B-lymphoblastoid lines and their relationship to cells in normal lymphoid tissues by Ling, N R, Hardie, D, Lowe, J, Johnson, G D, Khan, M, MacLennan, I C

“…Cells of 7 EBV-B-LCL, 10 Burkitt lines and 13 EBV-B-LCL/Burkitt line hybrids have been phenotyped for antigens of the major B cell clusters and for some other…”
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An analysis of myeloma plasma cell phenotype using antibodies defined at the IIIrd international workshop on human leucocyte differentiation antigens by JACKSON, N, LING, N. R, BALL, J, BROMIDGE, E, NATHAN, P. D, FRANKLIN, I. M

“…Fresh bone marrow from 43 cases of myeloma and three cases of plasma cell leukaemia has been phenotyped both by indirect immune-rosetting and, on fixed…”
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Two new IgA1-κ plasma cell leukaemia cell lines (JJN-1 & JJN-2) which proliferate in response to B cell stimulatory factor 2 by JACKSON, N, LOWE, J, BALL, J, BROMIDGE, E, LING, N. R, LARKINS, S, GRIFFITH, M. J, FRANKLIN, I. M

“…Two new cell lines with the phenotype of terminally differentiated B cells have been derived from the presentation bone marrow of a patient with plasma cell…”
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Monoclonal antibodies (McAbs) to determinants on human gamma chains: properties of antibodies showing subclass restriction or subclass specificity by Lowe, J, Bird, P, Hardie, D, Jefferis, R, Ling, N R

“…Thirteen monoclonal antibodies (McAbs) showing subclass-specific and subclass-restricted reactivity to human IgG have been produced by the hybridoma technique…”
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Human follicular dendritic cells (FDC): a study with monoclonal antibodies (MoAb) by JOHNSON, G. D, HARDIE, D. L, LING, N. R, MACLENNAN, I. C. M

“…A collection of new and established FDC-reactive MoAb has been used in an immunohistological study designed to throw light on (a) the nature of FDC (which are…”
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ELISA measurement of IgG subclass production in culture supernatants using monoclonal antibodies by Bird, P, Calvert, J E, Lowe, J, Duggan-Keen, M, Forouhi, N G, Seppälä, I, Ling, N R

“…Specific and sensitive ELISA to quantitate the human IgG subclasses in cell culture supernatants are described. These assays detect a minimum of 5 ng/ml IgG1,…”
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Synergy test for recognition of epitopes on soluble proteins; its application in the study of CD21 and CD23 antigens and their respective antibodies by Ling, N R, Brown, B, Hardie, D

“…Antigens such as CD21 and CD23, which express only one copy of an epitope require two monoclonal antibodies (mAbs) for their detection and estimation. This…”
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The separation of human serum IgG into subclass fractions by immunoaffinity chromatography and assessment of specific antibody activity by Bird, P, Lowe, J, Stokes, R P, Bird, A G, Ling, N R, Jefferis, R

“…Murine monoclonal antibodies ( McAbs ) with specificity for subclass-specific or subclass-restricted determinants on human IgG have been coupled to Sepharose…”
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Changes in the phenotype and immunoglobulin secretion of human B cells following co-culture with cells of an EBV+ lymphoblastoid line or fusion with mouse plasmacytoma cells. Studies in short-term and long-term culture by LING, N. R, LOWE, J. A

“…The mechanisms controlling immunoglobulin production have been studied in two types of immunoglobulin-secreting cell generated from human B cells. The first…”
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Percutaneous Pin Removal in the Outpatient Clinic—Do Children Require Analgesia? by Lim, Kevin Boon Leong, FRCS(Eng), FRCSEd(Orth), FAMS(Ortho Surgery), Abdullah, Sharifah Nazrah Syed, RN, Ong, Ling-Ling, RN, Wong, Mee-Leng, RN, Tan, Sara Shuhui, MD, Allen, John Carson, PhD

“…Background Percutaneous pins used in the surgical fixation of fractures in children are often removed in the outpatient clinic without the administration of…”
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Is the activated T helper stimulus able to induce Ig isotype switching in cultured human B cells? by Ling, N R, Lowe, J L

“…It is confirmed that large amounts of IgM, IgG, and IgA are produced when human B cells are cultured with T cells activated by immobilized CD3 antibody (CD3…”
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B cell proliferation in follicles, germinal centre formation and the site of neoplastic transformation in Burkitt's lymphoma by MacLennan, I C, Liu, Y L, Ling, N R

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Use of antibody-coated red cells for the sensitive detection of antigen and in rosette tests for cells bearing surface immunoglobulins by Ling, N R, Bishop, S, Jefferis

“…Conditions for an improved chromic chloride method for the attachment of antibody to red cells are described. The method, which is applicable to whole Ig…”
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