Search Results - "Ling, Mok Pooi"
-
1
Efficiency of newly formulated camptothecin with β-cyclodextrin-EDTA-Fe3O4 nanoparticle-conjugated nanocarriers as an anti-colon cancer (HT29) drug
Published in Scientific reports (08-09-2017)“…Camptothecin (CPT) is an anti-cancer drug that effectively treats various cancers, including colon cancer. However, poor solubility and other drawbacks have…”
Get full text
Journal Article -
2
Mechanisms and Impact of Biofilms and Targeting of Biofilms Using Bioactive Compounds—A Review
Published in Medicina (Kaunas, Lithuania) (18-08-2021)“…Biofilms comprising aggregates of microorganisms or multicellular communities have been a major issue as they cause resistance against antimicrobial agents and…”
Get full text
Journal Article -
3
Human Mesenchymal Stem Cells Expressing Erythropoietin Enhance Survivability of Retinal Neurons Against Oxidative Stress: An In Vitro Study
Published in Frontiers in cellular neuroscience (31-07-2018)“…Retinal degeneration is a prominent feature in ocular disorders. In exploring possible treatments, Mesenchymal Stem Cells (MSCs) have been recognized to yield…”
Get full text
Journal Article -
4
Structural, Optical, Antibacterial, and Anticancer Properties of Cerium Oxide Nanoparticles Prepared by Green Synthesis Using Morinda citrifolia Leaves Extract
Published in Bioinorganic chemistry and applications (2022)“…Currently, new advancements in the area of nanotechnology opened up new prospects in the field of medicine that could provide us with a solution for numerous…”
Get full text
Journal Article -
5
Camptothecin Encapsulated in β-Cyclodextrin-EDTA-Fe3O4 Nanoparticles Induce Metabolic Reprogramming Repair in HT29 Cancer Cells through Epigenetic Modulation: A Bioinformatics Approach
Published in Nanomaterials (Basel, Switzerland) (23-11-2021)“…Cancer progresses through a distinctive reprogramming of metabolic pathways directed by genetic and epigenetic modifications. The hardwired changes induced by…”
Get full text
Journal Article -
6
Stem Cell Therapy for Treatment of Ocular Disorders
Published in Stem cells international (01-01-2016)“…Sustenance of visual function is the ultimate focus of ophthalmologists. Failure of complete recovery of visual function and complications that follow…”
Get full text
Journal Article -
7
Modulatory and regenerative potential of transplanted bone marrow-derived mesenchymal stem cells on rifampicin-induced kidney toxicity
Published in Regenerative therapy (01-12-2018)“…Anti-tuberculosis agent rifampicin is extensively used for its effectiveness. Possible complications of tuberculosis and prolonged rifampicin treatment include…”
Get full text
Journal Article -
8
Cellular Reparative Mechanisms of Mesenchymal Stem Cells for Retinal Diseases
Published in International journal of molecular sciences (28-07-2017)“…The use of multipotent mesenchymal stem cells (MSCs) has been reported as promising for the treatment of numerous degenerative disorders including the eye. In…”
Get full text
Journal Article -
9
Effect of 660-nm LED photobiomodulation on the proliferation and chondrogenesis of meniscus-derived stem cells (MeSCs)
Published in Scientific reports (26-08-2024)“…Meniscus-derived stem cells (MeSCs), a unique type of MSC, have outstanding advantages in meniscal cytotherapy and tissue engineering, but the effects and…”
Get full text
Journal Article -
10
Fruit-Derived Polysaccharides and Terpenoids: Recent Update on the Gastroprotective Effects and Mechanisms
Published in Frontiers in pharmacology (22-06-2018)“…Ulceration in the stomach develops in peptic ulcer disease when there is a loss of protective mucosal layers, particularly in infection. Antibiotic therapy has…”
Get full text
Journal Article -
11
Treatment of HT29 Human Colorectal Cancer Cell Line with Nanocarrier-Encapsulated Camptothecin Reveals Histone Modifier Genes in the Wnt Signaling Pathway as Important Molecular Cues for Colon Cancer Targeting
Published in International journal of molecular sciences (13-11-2021)“…Cancer cells are able to proliferate in an unregulated manner. There are several mechanisms involved that propel such neoplastic transformations. One of these…”
Get full text
Journal Article -
12
Editorial: Neurodegenerative eye diseases: Molecular mechanisms of neurogenesis and therapeutic perspectives
Published in Frontiers in cellular neuroscience (26-10-2022)“…[...]Liu et al. studied whether activated NMNAT2 could be utilized as a gene therapy scheme for neuronal protection in EAE/optic neuritis. The protective…”
Get full text
Journal Article -
13
Nanoparticle-Encapsulated Camptothecin: Epigenetic Modulation in DNA Repair Mechanisms in Colon Cancer Cells
Published in Molecules (Basel, Switzerland) (06-09-2021)“…Molecular crosstalk between the cellular epigenome and genome converge as a synergistic driver of oncogenic transformations. Besides other pathways, epigenetic…”
Get full text
Journal Article -
14
Lung development, repair and cancer: A study on the role of MMP20 gene in adenocarcinoma
Published in PloS one (29-04-2021)“…Multiple matrix metalloproteinases have significant roles in tissue organization during lung development, and repair. Imbalance of proteinases may lead to…”
Get full text
Journal Article -
15
Leptospiral Infection, Pathogenesis and Its Diagnosis-A Review
Published in Pathogens (Basel) (01-02-2021)“…Leptospirosis is a perplexing conundrum for many. In the existing literature, the pathophysiological mechanisms pertaining to leptospirosis is still not…”
Get full text
Journal Article -
16
Empowering Mesenchymal Stem Cells for Ocular Degenerative Disorders
Published in International journal of molecular sciences (10-04-2019)“…Multipotent mesenchymal stem cells (MSCs) have been employed in numerous pre-clinical and clinical settings for various diseases. MSCs have been used in…”
Get full text
Journal Article -
17
Therapeutic Potential of Albumin Nanoparticles Encapsulated Visnagin in MDA-MB-468 Triple-Negative Breast Cancer Cells
Published in Molecules (Basel, Switzerland) (01-04-2023)“…Breast cancer is among the most recurrent malignancies, and its prevalence is rising. With only a few treatment options available, there is an immediate need…”
Get full text
Journal Article -
18
Human CD3+ T-Cells with the Anti-ERBB2 Chimeric Antigen Receptor Exhibit Efficient Targeting and Induce Apoptosis in ERBB2 Overexpressing Breast Cancer Cells
Published in International journal of molecular sciences (08-09-2017)“…Breast cancer is a common malignancy among women. The innate and adaptive immune responses failed to be activated owing to immune modulation in the tumour…”
Get full text
Journal Article -
19
Sagittal Jaw Relationship of Different Types of Cleft and Non-cleft Individuals
Published in Frontiers in pediatrics (05-05-2021)“…To investigate whether the craniofacial sagittal jaw relationship in patients with non-syndromic cleft differed from non-cleft (NC) individuals by artificial…”
Get full text
Journal Article -
20
Synthesis, Characterization, and Antiproliferative Effect of CuO-TiO2-Chitosan-Amygdalin Nanocomposites in Human Leukemic MOLT4 Cells
Published in Bioinorganic chemistry and applications (2022)“…The main aim of this study was to synthesize copper oxide- (CuO-) titanium oxide- (TiO2-) chitosan-amygdalin nanocomposites (CTCANc) and to characterize them…”
Get full text
Journal Article