Search Results - "Ling, Losee L."

In situ cultivation of previously uncultivable microorganisms using the ichip by Berdy, Brittany, Spoering, Amy L, Ling, Losee L, Epstein, Slava S

“…This protocol details the construction and use of the ichip, a platform developed to isolate previously uncultivable microorganisms from a range of…”
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A new antibiotic kills pathogens without detectable resistance by Ling, Losee L., Schneider, Tanja, Peoples, Aaron J., Spoering, Amy L., Engels, Ina, Conlon, Brian P., Mueller, Anna, Schäberle, Till F., Hughes, Dallas E., Epstein, Slava, Jones, Michael, Lazarides, Linos, Steadman, Victoria A., Cohen, Douglas R., Felix, Cintia R., Fetterman, K. Ashley, Millett, William P., Nitti, Anthony G., Zullo, Ashley M., Chen, Chao, Lewis, Kim

“…Antibiotic resistance is spreading faster than the introduction of new compounds into clinical practice, causing a public health crisis. Most antibiotics were…”
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Uncultured microorganisms as a source of secondary metabolites by Lewis, Kim, Epstein, Slava, D'Onofrio, Anthony, Ling, Losee L

“…The vast majority of microbial species are ‘uncultured’ and do not grow under laboratory conditions. This has led to the development of a number of methods to…”
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Biosynthesis and Mechanism of Action of the Cell Wall Targeting Antibiotic Hypeptin by Wirtz, Daniel A., Ludwig, Kevin C., Arts, Melina, Marx, Carina E., Krannich, Sebastian, Barac, Paul, Kehraus, Stefan, Josten, Michaele, Henrichfreise, Beate, Müller, Anna, König, Gabriele M., Peoples, Aaron J., Nitti, Anthony, Spoering, Amy L., Ling, Losee L., Lewis, Kim, Crüsemann, Max, Schneider, Tanja

“…Hypeptin is a cyclodepsipeptide antibiotic produced by Lysobacter sp. K5869, isolated from an environmental sample by the iChip technology, dedicated to the…”
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Teixobactin Provides Protection against Inhalation Anthrax in the Rabbit Model by Lawrence, William S., Peel, Jennifer E., Sivasubramani, Satheesh K., Baze, Wallace B., Whorton, Elbert B., Beasley, David W. C., Comer, Jason E., Hughes, Dallas E., Ling, Losee L., Peterson, Johnny W.

“…The use of antibiotics is a vital means of treating infections caused by the bacteria Bacillus (B.) anthracis. Importantly, with the potential future use of…”
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Neocitreamicins I and II, Novel Antibiotics with Activity against Methicillin-Resistant Staphylococcus aureus and Vancomycin-Resistant Enterococci by Peoples, Aaron J, Zhang, Qibo, Millett, William P, Rothfeder, Mithra T, Pescatore, Brian C, Madden, Anne A, Ling, Losee L, Moore, Charles M

“…Two novel antibiotics, neocitreamicins I and II, were isolated from a fermentation broth of a Nocardia strain. This producing strain was obtained using an in…”
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Crystal structure of the N-terminal domain of MtClpC1 in complex with the anti-mycobacterial natural peptide Lassomycin by Jagdev, Manas K., Tompa, Dharma R., Ling, Losee L., Peoples, Aaron J., Dandapat, Jagneshwar, Mohapatra, Chinmayee, Lewis, Kim, Vasudevan, Dileep

“…Antibiotics form our frontline therapy against disease-causing bacteria. Unfortunately, antibiotic resistance is becoming more common, threatening a future…”
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Synthesis and Stereochemical Determination of the Peptide Antibiotic Novo29 by Krumberger, Maj, Li, Xingyue, Kreutzer, Adam G., Peoples, Aaron J., Nitti, Anthony G., Cunningham, Andrew M., Jones, Chelsea R., Achorn, Catherine, Ling, Losee L., Hughes, Dallas E., Nowick, James S.

“…This paper describes the synthesis and stereochemical determination of Novo29 (clovibactin), a new peptide antibiotic that is related to teixobactin and is…”
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Identification and Characterization of Inhibitors of Bacterial Enoyl-Acyl Carrier Protein Reductase by LING, Losee L, JUN XIAN, YIBIN XIANG, MOIR, Donald T, ALI, Syed, BOLIN GENG, JUN FAN, MILLS, Debra M, ARVANITES, Anthony C, ORGUEIRA, Hernan, ASHWELL, Mark A, CARMEL, Gilles

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Erratum: A new antibiotic kills pathogens without detectable resistance by Ling, Losee L., Schneider, Tanja, Peoples, Aaron J., Spoering, Amy L., Engels, Ina, Conlon, Brian P., Mueller, Anna, Schäberle, Till F., Hughes, Dallas E., Epstein, Slava, Jones, Michael, Lazarides, Linos, Steadman, Victoria A., Cohen, Douglas R., Felix, Cintia R., Fetterman, K. Ashley, Millett, William P., Nitti, Anthony G., Zullo, Ashley M., Chen, Chao, Lewis, Kim

“…Nature 517, 455–459 (2015); doi:10.1038/nature14098 In Fig. 3d of this Article, the ‘2:1’ and ‘1:1’ labels at the bottom of the panel were inadvertently…”
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Biosynthesis and Mechanism of Action of the Cell Wall Targeting Antibiotic Hypeptin by Wirtz, Daniel A., Ludwig, Kevin C., Arts, Melina, Marx, Carina E., Krannich, Sebastian, Barac, Paul, Kehraus, Stefan, Josten, Michaele, Henrichfreise, Beate, Müller, Anna, König, Gabriele M., Peoples, Aaron J., Nitti, Anthony, Spoering, Amy L., Ling, Losee L., Lewis, Kim, Crüsemann, Max, Schneider, Tanja

“…Hypeptin is a cyclodepsipeptide antibiotic produced by Lysobacter sp. K5869, isolated from an environmental sample by the iChip technology, dedicated to the…”
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Isofuranonaphthoquinone Produced by an Actinoplanes Isolate by Zhang, Qibo, Peoples, Aaron J, Rothfeder, Mithra T, Millett, William P, Pescatore, Brian C, Ling, Losee L, Moore, Charles M

“…A new isofuranonaphthoquinone, 7,8-dihydroxy-1-methylnaphtho[2,3-c]furan-4,9-dione, was isolated from cultures of an Actinoplanes isolate obtained using an in…”
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Microbial pathogen genomes - new strategies for identifying therapeutic and vaccine targets by Opperman, Timothy, Ling, Losee L, Moir, Donald T

“…Efficient mining of genomic sequence information from multiple pathogens for therapeutic and vaccine targets requires efficient tools. Fortunately, robust…”
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Teixobactin kills bacteria by a two-pronged attack on the cell envelope by Shukla, Rhythm, Lavore, Francesca, Maity, Sourav, Derks, Maik G. N., Jones, Chelsea R., Vermeulen, Bram J. A., Melcrová, Adéla, Morris, Michael A., Becker, Lea Marie, Wang, Xiaoqi, Kumar, Raj, Medeiros-Silva, João, van Beekveld, Roy A. M., Bonvin, Alexandre M. J. J., Lorent, Joseph H., Lelli, Moreno, Nowick, James S., MacGillavry, Harold D., Peoples, Aaron J., Spoering, Amy L., Ling, Losee L., Hughes, Dallas E., Roos, Wouter H., Breukink, Eefjan, Lewis, Kim, Weingarth, Markus

“…Antibiotics that use novel mechanisms are needed to combat antimicrobial resistance 1 – 3 . Teixobactin 4 represents a new class of antibiotics with a unique…”
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