Search Results - "Ling, Kevin"
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Alginate/chitosan microparticles for gastric passage and intestinal release of therapeutic protein nanoparticles
Published in Journal of controlled release (10-02-2019)“…Enzymes with intracellular activity have significant potential to treat diseases. Protein nanoparticles (NPs) considerably enhance intracellular delivery of…”
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Journal Article -
2
Protein Nanoparticle Charge and Hydrophobicity Govern Protein Corona and Macrophage Uptake
Published in ACS applied materials & interfaces (28-10-2020)“…Protein nanoparticles are biomaterials composed entirely of proteins, with the protein sequence and structure determining the nanoparticle physicochemical…”
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Journal Article -
3
Effects of sustained GABA releasing implants on pancreatic islets in mice
Published in Drug delivery and translational research (01-10-2021)“…Gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter that is strongly and selectively synthesized in and secreted from pancreatic beta cells…”
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Journal Article -
4
Construction of a 5G-based, three-dimensional, and efficiently connected emergency medical management system
Published in Heliyon (01-03-2023)“…Shenzhen is unique in its need for ad hoc responses to emergencies. The need for emergency medicine also demonstrates a trend of sustained growth. A…”
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Journal Article -
5
Effects of PEG-Based Thermoresponsive Polymer Brushes on Fibroblast Spreading and Gene Expression
Published in Cellular and molecular bioengineering (01-09-2013)“…The use of thermoresponsive polymer (TRP) substrates, such as PNIPAM, has become a valuable tool for the gentle detachment of cells from their culture surface…”
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Journal Article -
6
Gender-Specific Total Knee Arthroplasty in Singaporean Women
Published in Journal of orthopaedic surgery (Hong Kong) (01-08-2015)“…Purpose. To compare the outcome of 145 women who underwent conventional total knee arthroplasty (TKA) with 77 women who underwent gender-specific TKA. Methods…”
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Journal Article -
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Carboxymethyl sago pulp/chitosan hydrogel as an immobilization medium for activated sludge for p‐nitrophenol biodegradation
Published in Journal of applied polymer science (20-05-2019)“…ABSTRACT In this study, carboxymethyl sago pulp (CMSP) derived from sago waste was successfully crosslinked with ferric ions in the presence of chitosan…”
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Journal Article -
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Discovery of Novel, First-in-Class Allosteric Modulators of MALT1 Scaffolding Function with Differentiated Pharmacology for NFκB-Driven Malignancies
Published in Blood (02-11-2023)“…Constitutive activation of NFκB is an oncogenic driver for many lymphoid and selected solid tumor malignancies. BTK inhibitors, which affect the upstream NFκB…”
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Bioengineering Bacterially Derived Immunomodulants: A Therapeutic Approach to Inflammatory Bowel Disease
Published in ACS nano (24-10-2017)“…Bacterial enteric pathogens have evolved efficient mechanisms to suppress mammalian inflammatory and immunoregulatory pathways. By exploiting the evolutionary…”
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Journal Article -
10
Evaluating cellular biocompatibility on thermo‐responsive polymer brushes
Published in The FASEB journal (01-04-2011)“…One approach to successfully replacing tissue lost to trauma or disease relies on the successful growth of tissue ex vivo. In traditional cell culture, cells…”
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Journal Article -
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O-014 Bioengineering Bacterially Derived Immunomodulants: A Novel Therapeutic Approach to Inflammatory Disease
Published in Inflammatory bowel diseases (01-12-2013)“…The purpose of this study was to exploit the evolutionary relationship of gut and pathogenic bacteria to develop novel mucosal therapeutics. Certain bacterial…”
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Journal Article -
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Abstract 345: Development of a novel and direct peptide Helicon࣪ inhibitor of β-catenin-TCF interaction with in vivo validation of transcriptional modulation and anti-tumor activity
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Abstract Wnt pathway mutations can be found in nearly all colorectal cancers and a significant number of cancers of the liver, breast, prostate, endometrium…”
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Journal Article -
13
The impact of superstar CEOs on financial reporting practices and firm performance
Published 01-01-2007“…The objective of this study is to examine the impact of managerial reputation on the financial reporting practices of firms and their operating performance…”
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Dissertation -
14
Autonomous Maritime Landings for Low-Cost VTOL Aerial Vehicles
Published in 2014 Canadian Conference on Computer and Robot Vision (01-05-2014)“…Autonomous landing of quad rotor UAV on a maritime vessel is a challenging task, as low cost sensors, unknown movements of the landing surface, and external…”
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Conference Proceeding -
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The impact of superstar CEOs on financial reporting practices and firm performance
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Dissertation