Search Results - "Ling, Hongwei"

Bamboo leaf extract ameliorates diabetic nephropathy through activating the AKT signaling pathway in rats by Ying, Changjiang, Mao, Yizhen, Chen, Lei, Wang, Shanshan, Ling, Hongwei, Li, Wei, Zhou, Xiaoyan

“…Diabetic nephropathy (DN) is one of the most severe diabetic complication and it is becoming become a worldwide epidemic, accounting for approximately…”
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Predictors of glycemic and weight responses to exenatide in patients with type 2 diabetes mellitus by Huang, Yuhan, Yu, Yanan, Hu, Ruonan, Xu, Ke, Wang, Tao, Ling, Hongwei, Han, Jia, Lv, Dongmei

“…Objective This study aimed to identify reliable predictors of haemoglobin A1c (HbA1c) reduction and weight loss within 6 months after treatment with exenatide…”
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Effects of PPARD gene variants on the therapeutic responses to exenatide in chinese patients with type 2 diabetes mellitus by Song, Jinfang, Li, Na, Hu, Ruonan, Yu, Yanan, Xu, Ke, Ling, Hongwei, Lu, Qian, Yang, Tingting, Wang, Tao, Yin, Xiaoxing

“…Background Exenatide is a GLP-1R agonist that often exhibits considerable interindividual variability in therapeutic efficacy. However, there is no evidence…”
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Real-time risk assessment of aircraft landing based on finite element-virtual prototype-machine learning co-simulation on wet runways by Xingyi Zhu, Yanan Wu, Yang Yang, Yafeng Pang, Hongwei Ling, Dawei Zhang

“…The safety of aircraft landing on wet runways is of great importance in runway risk management. In order to ensure landing safety on wet runways, real-time…”
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Glucose fluctuation increased mesangial cell apoptosis related to AKT signal pathway by Ying, Changjiang, Wang, Shanshan, Lu, Yan, Chen, Lei, Mao, Yizhen, Ling, Hongwei, Cheng, Xingbo, Zhou, Xiaoyan

“…Blood glucose fluctuation is an important factor for the development of diabetic complications. Glucose fluctuation aggravated the renal injury in diabetic…”
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CircARHGAP12 Triggers Mesenchymal Stromal Cell Autophagy to Facilitate its Effect on Repairing Diabetic Wounds by Sponging miR-301b-3p/ATG16L1 and miR-301b-3p/ULK2 by Meng, Fandong, Shen, Fengjie, Ling, Hongwei, Jin, Peisheng, Zhou, Dongmei, Li, Qiang

“…Circular RNAs have been confirmed to play vital roles in the development of human diseases. Nevertheless, their effects on modulating mesenchymal stromal cells…”
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Age Moderates the Impact of TRAbs on Thyroid Hormones and Hepatic Function in Patients with Graves' Disease by Guo, Kai, Ling, Hongwei, Zhou, Xiaoyan, Ying, Changjiang

“…Thyrotropin receptor antibodies (TRAbs) play a significant role in the course of hepatic dysfunction (HDF) in patients with Graves' disease (GD). However, few…”
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Hsa_circ_0008500 inhibits apoptosis of adipose‐derived stem cells under high glucose through hsa‐miR‐1273h‐5p/ELK1 axis by Meng, Fandong, Shen, Fengjie, Chu, Xuan, Ling, Hongwei, Qiao, Yun, Liu, Deshan

“…Preliminary researches have confirmed that the number of apoptosis of adipose tissue‐derived stem cells (ADSCs) in patients with diabetes is significantly…”
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1861-LB: Efficacy and Safety of HRS9531, a Novel Dual GLP-1/GIP Receptor Agonist, in Obese Adults—A Phase 2 Trial by ZHAO, LIN, ZHU, DAN, LIU, DEXUE, PAN, TIANRONG, WANG, DONGJI, HUI, YUAN, LING, HONGWEI, CAI, HANQIN, ZENG, MEIFANG, ZUO, YUE, SUN, YUQI, WANG, YIKE, LI, XIAOYING

“…Introduction: HRS9531, a novel dual GLP-1 and GIP receptor agonist, has shown prominent efficacy in glycemic control and weight loss in phase 1 trials. This…”
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Efficacy and safety of DBPR108 (prusogliptin) as an add‐on to metformin therapy in patients with type 2 diabetes: A 24‐week, multi‐centre, randomized, double‐blind, placebo‐controlled, superiority, phase III clinical trial by Xu, Jianping, Ling, Hongwei, Geng, Jianlin, Huang, Yanli, Xie, Ying, Zheng, Huiping, Niu, Huikun, Zhang, Tianhao, Yuan, Jing, Xiao, Xinhua

“…Aim To evaluate the efficacy and safety of DBPR108 (prusogliptin), a novel dipeptidyl peptidase‐4 (DPP‐4) inhibitor, as an add‐on therapy in patients with type…”
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Effect of filler on thermodynamic and mechanical behaviour of asphalt mastic: a MD simulation study by Zhu, Xingyi, Du, Zhao, Ling, Hongwei, Chen, Long, Wang, Yuhong

“…To fully understand the filler reinforcement mechanism in asphalt mastic, molecular dynamic (MD) simulation was adopted to explore the effect of mineral filler…”
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Blood glucose fluctuation accelerates renal injury involved to inhibit the AKT signaling pathway in diabetic rats by Ying, Changjiang, Zhou, Xiaoyan, Chang, Zhenzhen, Ling, Hongwei, Cheng, Xingbo, Li, Wei

“…Blood glucose fluctuation is associated with diabetic nephropathy. However, the mechanism by which blood glucose fluctuation accelerates renal injury is not…”
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Preoperative platelet distribution width‐to‐platelet ratio combined with serum thyroglobulin may be objective and popularizable indicators in predicting papillary thyroid carcinoma by Jin, Jin, Wu, Guihua, Ruan, Chengwei, Ling, Hongwei, Zheng, Xueman, Ying, Changjiang, Zhang, Ying

“…Objectives The incidence of papillary thyroid carcinoma (PTC) has increased more rapidly than that of any other cancer type in China. Early indicators with…”
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Prefabricated Flexible Conductive Composite Overlay for Active Deicing and Snow Melting by Yang, Jian, Zhu, Xingyi, Li, Lihan, Ling, Hongwei, Zhou, Peiting, Cheng, Zhihao, Su, Aiwu, Du, Yong

“…AbstractThis study aims to develop a new self-deicing technology that can clear ice/snow with high efficiency and achieve rapid assembly on site. A…”
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Predictive factors associated with glycaemic response to exenatide in Chinese patients with type 2 diabetes mellitus by Wang, Tao, Zhang, Fan, Wang, Xiaotong, Li, Xizhi, Ling, Hongwei, Lv, Dongmei, Yin, Xiaoxing, Lu, Qian

“…What is known and objective Exenatide is widely used in the treatment of type 2 diabetes mellitus (T2DM) because of its established effect on lowering glucose…”
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Efficacy and safety of insulin degludec biosimilar B01411 versus originator insulin degludec in Chinese patients with type 2 diabetes inadequately controlled on oral antidiabetic drugs: a multicenter, randomized, open-label, phase 3 study by Ji, Linong, Gao, Leili, Cheng, Zhifeng, Ma, Guoqing, Li, Shu, Wang, Haifang, Liu, Jie, Lu, Yibing, Liu, Meiying, Geng, Jianlin, Gao, Yunming, Ling, Hongwei, Sun, Wenli, Song, Chengwei, Sun, Jingfang

“…To compare the efficacy and safety of insulin degludec biosimilar B01411 (HS-IDeg) with originator insulin degludec-Tresiba (NN-IDeg) in Chinese patients with…”
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Zeaxanthin ameliorates high glucose-induced mesangial cell apoptosis through inhibiting oxidative stress via activating AKT signalling-pathway by Ying, Changjiang, Chen, Lei, Wang, Shanshan, Mao, Yizhen, Ling, Hongwei, Li, Wei, Zhou, Xiaoyan

“…Abstract Oxidative stress is a critical factor in the pathophysiology of diabetic kidney disease. Previous study shows that hyperglycaemia aggravates renal…”
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Glucose variability aggravates cardiac fibrosis by altering AKT signalling path by Ying, Changjiang, Liu, Ting, Ling, Hongwei, Cheng, Mingyue, Zhou, Xiaoyan, Wang, Shanshan, Mao, Yizhen, Chen, Lei, Zhang, Runze, Li, Wei

“…To study the effect of blood glucose variability on cardiac fibrosis and its mechanism in a model of diabetic cardiomyopathy. A total of 45 Sprague Dawley rats…”
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Glycemic variability indices determined by self-monitoring of blood glucose are associated with β-cell function in Chinese patients with type 2 diabetes by Zhang, Yusheng, Dai, Jiao, Han, Xiao, Zhao, Yue, Zhang, Hui, Liu, Xuan, Li, Wei, Ling, Hongwei, Zhou, Xiaoyan, Ying, Changjiang

“…•SMBG parameters are associated with β-cell function in Chinese T2DM patients•SMBG parameters are associated with β-cell function, independent of HbA1c.•We…”
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Carbonyl-Directed Addition of N‑Alkylhydroxylamines to Unactivated Alkynes: Regio- and Stereoselective Synthesis of Ketonitrones by Liu, Yilin, Feng, Xiangqing, Liu, Yanyun, Lin, Hongwei, Li, Yuanxiang, Gong, Yingying, Cao, Lei, Chen, Liping

“…A variety of ketonitrones were synthesized in moderate to excellent yields with high chemo-, regio-, and stereoselectivity by using carbonyl-directed addition…”
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