Search Results - "Linetsky, M"

Automated Assessment of the DWI-FLAIR Mismatch in Patients with Acute Ischemic Stroke: Added Value to Routine Clinical Practice by Tavakkol, E, Kihira, S, McArthur, M, Polson, J, Zhang, H, Arnold, C W, Yoo, B, Linetsky, M, Salehi, B, Ledbetter, L, Kim, C, Jahan, R, Duckwiler, G, Saver, J L, Liebeskind, D S, Nael, K

“…The DWI-FLAIR mismatch is used to determine thrombolytic eligibility in patients with acute ischemic stroke when the time since stroke onset is unknown…”
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Arterial spin-labeling perfusion MRI stratifies progression-free survival and correlates with epidermal growth factor receptor status in glioblastoma by Qiao, X J, Ellingson, B M, Kim, H J, Wang, D J J, Salamon, N, Linetsky, M, Sepahdari, A R, Jiang, B, Tian, J J, Esswein, S R, Cloughesy, T F, Lai, A, Nghiemphu, L, Pope, W B

“…Glioblastoma is a common primary brain tumor with a poor but variable prognosis. Our aim was to investigate the feasibility of MR perfusion imaging by using…”
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Perfusion deficits detected by arterial spin-labeling in patients with TIA with negative diffusion and vascular imaging by Qiao, X J, Salamon, N, Wang, D J J, He, R, Linetsky, M, Ellingson, B M, Pope, W B

“…A substantial portion of clinically diagnosed TIA cases is imaging-negative. The purpose of the current study is to determine if arterial spin-labeling is…”
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Convenient synthesis of GOLD and MOLD and identification of their oxidation products in vitro and in vivo by Linetsky, M. D, Shipova, E. V

“…Two Lys-Lys crosslinks, 1,3-bis-(5-amino-5-carboxypentyl)-1H-imidazolium (GOLD) and 1,3-bis(5-amino-5-carboxypentyl)-4-methyl-1H-imidazolium (MOLD) salts, have…”
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Intracochlear schwannoma presenting as diffuse cochlear enhancement: diagnostic challenges of a rare cause of deafness by Miller, M. E., Moriarty, J. M., Linetsky, M., Lai, C., Ishiyama, A.

“…Intracochlear schwannoma is a rare, treatable, cause of unilateral hearing loss. Due to the small size, position, and variable clinical and imaging features,…”
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Dehydroalanine crosslinks in human lens by Linetsky, Mikhail, Hill, J.M.W., LeGrand, Roy D., Hu, F.

“…This study was conducted to develop a methodology for the purification and detection of histidinoalanine, lanthionine and lysinoalanine in the lens tissue…”
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Glutathionylation of lens proteins through the formation of thioether bond by Linetsky, Mikhail, LeGrand, Roy D

“…Formation of lanthionine, a dehydroalanine crosslink, is associated with aging of the human lens and cataractogenesis. In this study we investigated whether…”
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Aeronautical situational awareness - airport surface by Linetsky, Vladimir M., Ivancic, William D., Vaden, Karl R.

“…This paper advocates for a specific design approach, based on simple principals, yet addresses challenges faced by the system engineers when designing complex…”
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The Generation of Superoxide Anions in Glycation Reactions with Sugars, Osones, and 3-Deoxyosones by Ortwerth, B.J., James, Hongying, Simpson, Gregory, Linetsky, Mikhail

“…Glycoxidation is a process whereby glycated proteins chemically generate oxygen free radicals. Superoxide anion formation was measured by the superoxide…”
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Superoxide Free Radical Generation by Amadori Compounds:  The Role of Acyclic Forms and Metal Ions by Mossine, Valeri V, Linetsky, Mikhail, Glinsky, Gennadi V, Ortwerth, Beryl J, Feather, Milton S

“…Generation of oxygen free radicals by glycated proteins is widely believed to be one of the causes of oxidative stress in diabetes and aging. Metal ion…”
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Quantitation of the Singlet Oxygen Produced by UVA Irradiation of Human Lens Proteins by Linetsky, Mikhail, Ortwerth, B. J.

“…Ultraviolet irradiation of aged human lens proteins in vitro causes extensive photolytic damage of His and Trp residues. Protection by sodium azide argues for…”
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Effect of UVA Light on the Activity of Several Aged Human Lens Enzymes by Linetsky, Mikhail, Chemoganskiy, Vitaliy G, Hu, Fang, Ortwerth, Beryl J

“…To determine the effect of UVA irradiation on the specific activities of several protective and metabolic enzymes in aged human lenses. Intact human lenses…”
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Quantitation of the reactive oxygen species generated by the UVA irradiation of ascorbic acid-glycated lens proteins by Linetsky, M, Ortwerth, B J

“…The oxidation products of ascorbic acid rapidly glycate proteins and produce protein-bound, advanced glycation endproducts. These endproducts can absorb UVA…”
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The generation of hydrogen peroxide by the UVA irradiation of human lens proteins by Linetsky, M, Ortwerth, B J

“…The water-insoluble proteins from aged human lens are known to contain protein-bound chromophores that act as UVA senisitizers. The irradiation of a…”
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The Relative UV Sensitizer Activity of Purified Advanced Glycation Endproducts by Ortwerth, B. J., Prabhakaram, Malladi, Nagaraj, R. H., Linetsky, Mikhail

“…— The oxidation products of ascorbic acid react with lens proteins to form advanced glycation endproducts (AGE) that are capable of generating reactive oxygen…”
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The Aggregation in Human Lens Proteins Blocks the Scavenging of UVA-Generated Singlet Oxygen by Ascorbic Acid and Glutathione by Linetsky, Mikhail, Ranson, Nicholas, Ortwerth, B.J.

“…One hour of UVA irradiation of air-saturated solutions of 2 mg/mL solubilized lens protein aggregates from aged human lens is able to produce an accumulated…”
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Studies on the Mechanism of the UVA Light-Dependent Loss of Glutathione Reductase Activity in Human Lenses by Linetsky, Mikhail, Hill, Jana M. W, Chemoganskiy, Vitaliy G, Hu, Fang, Ortwerth, Beryl J

“…To determine the mechanism that leads to the UVA light-dependent loss of glutathione reductase (GR) activity in human lens (HL). Both the HL water-soluble (WS)…”
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Spontaneous Generation of Superoxide Anion by Human Lens Proteins and by Calf Lens Proteins Ascorbylated In Vitro by LINETSKY, MIKHAIL, JAMES, HONGYING L., ORTWERTH, B.J.

“…The proteins isolated from aged human lenses and brunescent cataracts exhibit extensive disulfide bond formation. Diabetic rat lenses similarly contain…”
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The Generation of Superoxide Anion by the UVA Irradiation of Human Lens Proteins by LINETSKY, MIKHAIL, JAMES, H.-L., ORTWERTH, B.J.

“…In this study we report the generation of superoxide anion and hydrogen peroxide by a water-insoluble protein fraction from aged human lenses in response to…”
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Ascorbic acid glycation of lens proteins produces UVA sensitizers similar to those in human lens by Ortwerth, B J, Linetsky, M, Olesen, P R

“…Soluble calf lens proteins were extensively glycated during a 4 week incubation with ascorbic acid in the presence of oxygen. Amino acid analysis of the…”
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