Search Results - "Lindstedt, EL"
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Myeloperoxidase Inhibition in Heart Failure With Preserved or Mildly Reduced Ejection Fraction: SATELLITE Trial Results
Published in Journal of cardiac failure (01-01-2024)“…•Does treatment for 90 days with 5 mg oral doses of the myeloperoxidase inhibitor AZD4831 decrease myeloperoxidase specific activity in patients with heart…”
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Safety and efficacy of the 5-lipoxygenase-activating protein inhibitor AZD5718 in patients with recent myocardial infarction: The phase 2a FLAVOUR study
Published in International journal of cardiology (15-10-2022)“…Leukotrienes are pro-inflammatory vasoactive lipid mediators implicated in the pathophysiology of atherosclerotic cardiovascular disease. We studied the effect…”
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Structure of the PPARα and -γ Ligand Binding Domain in Complex with AZ 242; Ligand Selectivity and Agonist Activation in the PPAR Family
Published in Structure (London) (01-08-2001)“…Background: The peroxisome proliferator-activated receptors (PPAR) are ligand-activated transcription factors belonging to the nuclear receptor family. The…”
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Low dose of the liver X receptor agonist, AZ876, reduces atherosclerosis in APOE3Leiden mice without affecting liver or plasma triglyceride levels
Published in British journal of pharmacology (01-04-2011)“…BACKGROUND AND PURPOSE Liver X receptor (LXR) agonists are atheroprotective but often induce hypertriglyceridaemia and liver steatosis. We investigated the…”
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Renal artery aneurysms. Natural history and prognosis
Published in Annals of surgery (01-03-1983)“…Eighty-three patients out of 8,525 undergoing renal angiography during the years 1970-1979 were found to have renal artery aneurysm, which in six patients were…”
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