Search Results - "Lindsey, J W"

Continuous long-term immunomodulatory therapy in relapsing multiple sclerosis: results from the 15-year analysis of the US prospective open-label study of glatiramer acetate by Ford, C., Goodman, AD, Johnson, K., Kachuck, N., Lindsey, JW, Lisak, R., Luzzio, C., Myers, L., Panitch, H., Preiningerova, J., Pruitt, A., Rose, J., Rus, H., Wolinsky, J.

“…The ongoing US Glatiramer Acetate (GA) Trial is the longest evaluation of continuous immunomodulatory therapy in relapsing—remitting multiple sclerosis (RRMS)…”
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Sudden unexpected death on fingolimod by Lindsey, JW, Haden-Pinneri, K, Memon, NB, Buja, LM

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Quantitative PCR for Epstein–Barr virus DNA and RNA in multiple sclerosis by Lindsey, JW, Hatfield, LM, Crawford, MP, Patel, S

“…Background Epstein–Barr virus (EBV) is associated with MS, but it is not clear whether EBV plays a role in the pathogenesis of MS. Hypothesis We hypothesized…”
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Dexamethasone-induced Ras-related protein 1 is a potential regulatory protein in B lymphocytes by Lindsey, JW

“…Dexamethasone-induced Ras-related protein 1 (RASD1) is a protein of the Ras family which probably has a regulatory function. We demonstrate that Rasd1 mRNA is…”
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PCR for bacterial 16S ribosomal DNA in multiple sclerosis cerebrospinal fluid by LINDSEY, J. W, PATEL, S

“…The cause of multiple sclerosis (MS) is currently unknown. The hypothesis of this study is that MS is caused by a chronic bacterial infection of the central…”
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Variable results after rituximab in neuromyelitis optica by Lindsey, J.W, Meulmester, K.M, Brod, S.A, Nelson, F, Wolinsky, J.S

“…Abstract Our objective was to assess the efficacy of rituximab (RTX) in neuromyelitis optica (NMO). We conducted a retrospective review of cases personally…”
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Ingested IFN-α : Results of a pilot study in relapsing-remitting MS by BROD, S. A, LINDSEY, J. W, VRIESENDORP, F. S, AHN, C, HENNINGER, E, NARAYANA, P. A, WOLINSKY, J. S

“…To investigate whether ingested human recombinant interferon-alpha2a (IFN-alpha2a) was safe and whether treatment reduces the number of gadolinium-enhanced…”
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Antivirus immune activity in multiple sclerosis correlates with MRI activity by Latham, L. B., Lee, M. J., Lincoln, J. A., Ji, N., Forsthuber, T. G., Lindsey, J. W.

“…Objective The objective of this study was to determine whether reactivation of Epstein‐Barr (EBV) or activation of the anti‐EBV immune response correlates with…”
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Repeated treatment with chimeric anti-CD4 antibody in multiple sclerosis by Lindsey, J W, Hodgkinson, S, Mehta, R, Mitchell, D, Enzmann, D, Steinman, L

“…We treated 21 multiple sclerosis patients with two to four doses of cM-T412, a chimeric monoclonal antibody against the CD4 antigen found on helper/inducer T…”
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Epstein-Barr virus neutralizing and early antigen antibodies in multiple sclerosis by Lindsey, J. W., Hatfield, L. M., Vu, T.

“…Background:  Our objective was to determine whether antibodies against the Epstein–Barr virus (EBV) nuclear antigen‐1 (EBNA‐1), early antigen (EA), and EBV…”
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The antibody response to Epstein–Barr virions is altered in multiple sclerosis by Lindsey, J.W, Khan, U, Ansari, W, Powell, T, Wang, Y.H, Guirguis, M.S

“…Abstract Infection with Epstein–Barr virus (EBV) is associated with multiple sclerosis (MS), and patients with MS have an increased antibody response to some…”
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Epstein-Barr virus genotypes in multiple sclerosis by Lindsey, J. W., Patel, S., Zou, J.

“…Background –  Multiple sclerosis (MS) is associated with Epstein–Barr virus (EBV) infection, but the relationship between the virus and the disease is not…”
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Phase 1 clinical trial of chimeric monoclonal anti-CD4 antibody in multiple sclerosis by LINDSEY, J. W, HODGKINSON, S, STEINMAN, L, MEHTA, R, SIEGEL, R. C, MITCHELL, D. J, LIM, M, PIERCY, C, TRAM, T, DORFMAN, L, ENZMANN, D

“…We conducted an open trial of cM-T412, a chimeric monoclonal anti-CD4 antibody, in 29 patients with MS. This antibody caused a prompt and long-lasting…”
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The CombiRx trial of combined therapy with interferon and glatiramer acetate in relapsing remitting MS: Design and baseline characteristics by Lindsey, J.W, Scott, T.F, Lynch, S.G, Cofield, S.S, Nelson, F, Conwit, R, Gustafson, T, Cutter, G.R, Wolinsky, J.S, Lublin, F.D

“…Abstract Background Interferon-β1a (IFNB) and glatiramer acetate (GA) are distinct therapies which are both partially effective for relapsing MS. It is not…”
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Recurrent transverse myelitis, myasthenia gravis, and autoantibodies by Lindsey, J W, Albers, G W, Steinman, L

“…A 45-year-old man with a longstanding diagnosis of myasthenia gravis presented with four episodes of transverse myelitis in 5 years. Each episode improved…”
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Role of monkey midbrain near-response neurons in phoria adaptation by Morley, J W, Judge, S J, Lindsey, J W

“…1. One striking characteristic of the way in which accommodation and convergence of the eyes are organized is that although the two responses are usually…”
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Diverse T cell receptor Vβ gene usage in the central nervous system in experimental allergic encephalomyelitis by BELL, R. B, LINDSEY, J. W, SOBEL, R. A, HODGKINSON, S, STEINMAN, L

“…The repertoire of TCR V beta genes transcribed and expressed within the central nervous system was determined in mice with experimental allergic…”
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Immune regulatory effects of central nervous system antigens in culture by Lindsey, J. William, Jin, Rui

“…Evidence from several different experimental systems suggests that regulatory cells specific for self-antigens exist in the normal immune repertoire, and that…”
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Trimethylolpropane phosphate (TMPP) perfusion into the nucleus accumbens of the rat: electroencephalographic, behavioral and neurochemical correlates by Lindsey, J W, Prues, S L, Alva, C, Ritchie, G D, Rossi, 3rd, J

“…The infusion (0.13 mumol/infusion) of the convulsant trimethylolpropane phosphate (TMPP) into the nucleus accumbens (NA) of adults Sprague-Dawley rats reliably…”
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Usage of T cell receptor beta-chain variable gene is highly restricted at the site of inflammation in murine autoimmune uveitis by Rao, NA, Naidu, YM, Bell, R, Lindsey, JW, Pararajasegaram, G, Sun, Y, Steinman, L

“…Improved molecular methods allow identification of the specific autoaggressive T cells involved in autoimmune inflammations. In this study of…”
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