Search Results - "Lindsay, S.M."

AFM imaging of protein movements: Histone H2A–H2B release during nucleosome remodeling by Bash, R., Wang, H., Anderson, C., Yodh, J., Hager, G., Lindsay, S.M., Lohr, D.

“…Being able to follow assembly/disassembly reactions of biomolecular complexes directly at the single molecule level would be very useful. Here, we use an AFM…”
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Can an Atomic Force Microscope Sequence DNA Using a Nanopore? by Qamar, Shahid, Williams, Phil M., Lindsay, S.M.

“…R. Bension has proposed that single molecules of DNA could be sequenced rapidly, in long sequential reads, by reading off the force required to pull a tightly…”
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Measuring the microelastic properties of biological material by Tao, N.J., Lindsay, S.M., Lees, S.

“…We have used the atomic force microscope (AFM) to measure the local rigidity modulus at points on the surface of a section of hydrated cow tibia. These data…”
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Structure and stability of cytosine adlayers on Au(111): an in-situ STM study by Wandlowski, Th, Lampner, D., Lindsay, S.M.

“…The formation, structure and stability of cytosine adlayers on Au(111) in aqueous solution has been studied by current-potential, capacitance-potential,…”
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Atomic force microscopy of DNA and bacteriophage in air, water and propanol: the role of adhesion forces by Lyubchenko, Y.L., Oden, P.I., Lampner, D., Lindsay, S.M., Dunker, K.A.

“…We have developed a chemical treatment for the mica surface which allows blopolymers to be held in place for atomic force microscopy, even under water, using…”
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Evidence of Stage Shift in Women Diagnosed With Ovarian Cancer During Phase II of the United Kingdom Familial Ovarian Cancer Screening Study by Rosenthal, Adam N, Fraser, Lindsay S M, Philpott, Susan, Manchanda, Ranjit, Burnell, Matthew, Badman, Philip, Hadwin, Richard, Rizzuto, Ivana, Benjamin, Elizabeth, Singh, Naveena, Evans, D Gareth, Eccles, Diana M, Ryan, Andy, Liston, Robert, Dawnay, Anne, Ford, Jeremy, Gunu, Richard, Mackay, James, Skates, Steven J, Menon, Usha, Jacobs, Ian J

“…Purpose To establish the performance of screening with serum cancer antigen 125 (CA-125), interpreted using the risk of ovarian cancer algorithm (ROCA), and…”
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Scanning tunneling microscopy of mercapto-hexyl-oligonucleotides attached to gold by Rekesh, D., Lyubchenko, Y., Shlyakhtenko, L.S., Lindsay, S.M.

“…6-mercapto hexyl-oligonucleotides bind to a gold surface strongly enough to permit imaging by a scanning tunneling microscope (STM). STM images showed…”
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Bias-induced forces in conducting atomic force microscopy and contact charging of organic monolayers by Cui, X.D, Zarate, X, Tomfohr, J, Primak, A, Moore, A.L, Moore, T.A, Gust, D, Harris, G, Sankey, O.F, Lindsay, S.M

“…Contact electrification, a surface property of bulk dielectric materials, has now been observed at the molecular scale using conducting atomic force microscopy…”
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Potentiostatic deposition of DNA for scanning probe microscopy by Lindsay, S.M., Tao, N.J., DeRose, J.A., Oden, P.I., Lyubchenko YuL, Harrington, R.E., Shlyakhtenko, L.

“…We describe a procedure for reversible adsorption of DNA onto a gold electrode maintained under potential control. The adsorbate can be imaged by scanning…”
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Surface modification of graphene nanopores for protein translocation by Shan, Y P, Tiwari, P B, Krishnakumar, P, Vlassiouk, I, Li, W Z, Wang, X W, Darici, Y, Lindsay, S M, Wang, H D, Smirnov, S, He, J

“…Studies of DNA translocation through graphene nanopores have revealed their potential for DNA sequencing. Here we report a study of protein translocation…”
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Reproducible Measurement of Single-Molecule Conductivity by Cui, X. D., Primak, A., Zarate, X., Tomfohr, J., Sankey, O. F., Moore, A. L., Moore, T. A., Gust, D., Harris, G., Lindsay, S. M.

“…A reliable method has been developed for making through-bond electrical contacts to molecules. Current-voltage curves are quantized as integer multiples of one…”
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Evidence of Stage Shift in Women Diagnosed With Ovarian Cancer During Phase II of the United Kingdom Familial Ovarian Cancer Screening Study by Rosenthal, Adam N, Fraser, Lindsay S M, Philpott, Susan, Manchanda, Ranjit, Burnell, Matthew, Badman, Philip, Hadwin, Richard, Rizzuto, Ivana, Benjamin, Elizabeth, Singh, Naveena, Evans, D Gareth, Eccles, Diana M, Ryan, Andy, Liston, Robert, Dawnay, Anne, Ford, Jeremy, Gunu, Richard, Mackay, James, Skates, Steven J, Menon, Usha, Jacobs, Ian J

“…(Abstracted from J Clin Oncol 2017:35(13):1411–1420)For the randomized general population, the United Kingdom Collaborative Trial of Ovarian Cancer Screening…”
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Solution AFM Studies of Human Swi-Snf and Its Interactions with MMTV DNA and Chromatin by Wang, H., Bash, R., Lindsay, S.M., Lohr, D.

“…ATP-dependent nucleosome remodeling complexes are crucial for relieving nucleosome repression during transcription, DNA replication, recombination, and repair…”
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Electrochemical deposition of molecular adsorbates for in situ scanning probe microscopy by Nagahara, L A, Thundat, T, Oden, P I, Lindsay, S M, Rill, R L

“…We have studied gold and graphite electrodes in an electrochemistry cell under various solutions using the scanning tunneling microscope (STM). The gold (111)…”
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A Statistical Thermodynamic Model Applied to Experimental AFM Population and Location Data Is Able to Quantify DNA-Histone Binding Strength and Internucleosomal Interaction Differences between Acetylated and Unacetylated Nucleosomal Arrays by Solis, F.J., Bash, R., Yodh, J., Lindsay, S.M., Lohr, D.

“…Imaging of nucleosomal arrays by atomic force microscopy allows a determination of the exact statistical distributions for the numbers of nucleosomes per array…”
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Isolation of an scFv targeting BRG1 using phage display with characterization by AFM by Marcus, W.D., Wang, H., Lohr, D., Sierks, M.R., Lindsay, S.M.

“…Remodeling of chromatin is a vitally important event in processes such as transcription and replication. Brahma-related gene 1 (BRG1) protein is the major…”
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Using Atomic Force Microscopy to Study Nucleosome Remodeling on Individual Nucleosomal Arrays in Situ by Wang, H., Bash, R., Yodh, J.G., Hager, G., Lindsay, S.M., Lohr, D.

“…In eukaryotes, genomic processes like transcription, replication, repair, and recombination typically require alterations in nucleosome structure on specific…”
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Identification and Repair of Positive Binding Antibodies Containing Randomly Generated Amber Codons from Synthetic Phage Display Libraries by Marcus, Warren D., Lindsay, Stuart M., Sierks, Michael R.

“…Phage display technology allows for the rapid isolation and characterization of monoclonal antibodies that have vast potential for therapeutic and diagnostic…”
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Non-exponential tunneling in water near an electrode by Vaught, A., Jing, T.W., Lindsay, S.M.

“…We have measured the inverse decay length (κ) for tunneling in water between a Pt-Ir tip and an Au(111) surface. At 10 9 Ω κ = 0.92 ± 0.16 Å −1 (Au negative),…”
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Images of the DNA Double Helix in Water by Lindsay, S. M., Thundat, T., Nagahara, L., Knipping, U., Rill, R. L.

“…The scanning tunneling microscope can image uncoated DNA submerged in water. The grooves of the double helix were clearly resolved in images of the 146--base…”
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