Search Results - "Lindqvist, Anders"

A New Perspective in the Field of Cardiac Safety Testing through the Comprehensive In Vitro Proarrhythmia Assay Paradigm by Fermini, Bernard, Hancox, Jules C, Abi-Gerges, Najah, Bridgland-Taylor, Matthew, Chaudhary, Khuram W, Colatsky, Thomas, Correll, Krystle, Crumb, William, Damiano, Bruce, Erdemli, Gul, Gintant, Gary, Imredy, John, Koerner, John, Kramer, James, Levesque, Paul, Li, Zhihua, Lindqvist, Anders, Obejero-Paz, Carlos A, Rampe, David, Sawada, Kohei, Strauss, David G, Vandenberg, Jamie I

“…For the past decade, cardiac safety screening to evaluate the propensity of drugs to produce QT interval prolongation and Torsades de Pointes (TdP) arrhythmia…”
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Transmission and control of Salmonella in the pig feed chain: A conceptual model by Binter, Claudia, Straver, Judith Maria, Häggblom, Per, Bruggeman, Geert, Lindqvist, Per-Anders, Zentek, Jürgen, Andersson, Mats Gunnar

“…Infected breeder pigs and contaminated feed represent potential sources of Salmonella introduction to fattening pig herds and may thereby cause human…”
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Defective secretion of islet hormones in chromogranin-B deficient mice by Obermüller, Stefanie, Calegari, Federico, King, Angus, Lindqvist, Anders, Lundquist, Ingmar, Salehi, Albert, Francolini, Maura, Rosa, Patrizia, Rorsman, Patrik, Huttner, Wieland B, Barg, Sebastian

“…Granins are major constituents of dense-core secretory granules in neuroendocrine cells, but their function is still a matter of debate. Work in cell lines has…”
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Binding of calcium ions and SNAP-25 to the hexa EF-hand protein secretagogin by Rogstam, Annika, Linse, Sara, Lindqvist, Anders, James, Peter, Wagner, Ludwig, Berggård, Tord

“…Secretagogin is a hexa EF-hand protein, which has been identified as a novel potential tumour marker. In the present study, we show that secretagogin binds…”
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Selective nucleotide-release from dense-core granules in insulin-secreting cells by Obermůller, Stefanie, Lindqvist, Anders, Karanauskaite, Jovita, Galvanovskis, Juris, Rorsman, Patrik, Barg, Sebastian

“…Secretory granules of insulin-secreting cells are used to store and release peptide hormones as well as low-molecular-weight compounds such as nucleotides…”
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Effects of intracellular fluoride and temperature on hERG blocker potency in vitro by Lindqvist, Anders

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Automatic estimation of hNav1.5 channel inactivation improves pharmacological evaluation using the new adaptive protocol feature on QPatchII by Lindqvist, Anders

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Estimating hERG drug binding using temperature-controlled high-throughput automated patch-clamp by Lindqvist, Anders

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Temperature effect on hERG channel pharmacology measured by using the Qube automated patch clamp system by Lindqvist, Anders, Mattson, Göran

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Qube384 As a Tool for Assay Optimization of CiPA Cells and Protocols by Using Multiple IC, EC Solutions and hERG, Nav1.5 and Cav1.2 on the Same QChip by Yu, Weifeng, Løjkner, Lars Damgaard, Lindqvist, Anders

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Biophysical and Pharmacological Characterization of Multiple Nav Subtypes on QUBE by Korsgaard, Mads P., Lindqvist, Anders, Friis, Søren, Christensen, Mette T.

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Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells by Kramer, James, Himmel, Herbert M., Lindqvist, Anders, Stoelzle-Feix, Sonja, Chaudhary, Khuram W., Li, Dingzhou, Bohme, Georg Andrees, Bridgland-Taylor, Matthew, Hebeisen, Simon, Fan, Jingsong, Renganathan, Muthukrishnan, Imredy, John, Humphries, Edward S. A., Brinkwirth, Nina, Strassmaier, Tim, Ohtsuki, Atsushi, Danker, Timm, Vanoye, Carlos, Polonchuk, Liudmila, Fermini, Bernard, Pierson, Jennifer Beck, Gintant, Gary

“…Automated patch clamp (APC) instruments enable efficient evaluation of electrophysiologic effects of drugs on human cardiac currents in heterologous expression…”
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In education we trust: on handling the COVID-19 Pandemic in the Swedish welfare state by Lindblad, Sverker, Lindqvist, Anders, Runesdotter, Caroline, Wärvik, Gun-Britt

“…Keeping schools open was an active strategy in Sweden to meet the threats of the COVID-19 pandemic. In this article we analyze how a collection of welfare…”
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A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm by Ridder, Bradley J., Leishman, Derek J., Bridgland-Taylor, Matthew, Samieegohar, Mohammadreza, Han, Xiaomei, Wu, Wendy W., Randolph, Aaron, Tran, Phu, Sheng, Jiansong, Danker, Timm, Lindqvist, Anders, Konrad, Daniel, Hebeisen, Simon, Polonchuk, Liudmila, Gissinger, Evgenia, Renganathan, Muthukrishnan, Koci, Bryan, Wei, Haiyang, Fan, Jingsong, Levesque, Paul, Kwagh, Jae, Imredy, John, Zhai, Jin, Rogers, Marc, Humphries, Edward, Kirby, Robert, Stoelzle-Feix, Sonja, Brinkwirth, Nina, Rotordam, Maria Giustina, Becker, Nadine, Friis, Søren, Rapedius, Markus, Goetze, Tom A., Strassmaier, Tim, Okeyo, George, Kramer, James, Kuryshev, Yuri, Wu, Caiyun, Himmel, Herbert, Mirams, Gary R., Strauss, David G., Bardenet, Rémi, Li, Zhihua

“…hERG block potency is widely used to calculate a drug's safety margin against its torsadogenic potential. Previous studies are confounded by use of different…”
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School lockdown? Comparative analyses of responses to the COVID-19 pandemic in European countries by Lindblad, Sverker, Wärvik, Gun-Britt, Berndtsson, Inger, Jodal, Elsi-Brith, Lindqvist, Anders, Messina Dahlberg, Giulia, Papadopoulos, Dimitrios, Runesdotter, Caroline, Samuelsson, Katarina, Udd, Jonas, Wyszynska Johansson, Martina

“…The purpose of this article is to analyse how education and schooling took part in handling the early phase of the COVID-19 pandemic in eight European…”
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Corrigendum to “A systematic strategy for estimating hERG block potency and its implications in a new cardiac safety paradigm” [Toxicology and Applied Pharmacology volume 394C (2020) 114961] by Ridder, Bradley J., Leishman, Derek J., Bridgland-Taylor, Matthew, Samieegohar, Mohammadreza, Han, Xiaomei, Wu, Wendy W., Randolph, Aaron, Tran, Phu, Sheng, Jiansong, Danker, Timm, Lindqvist, Anders, Konrad, Daniel, Hebeisen, Simon, Polonchuk, Liudmila, Gissinger, Evgenia, Renganathan, Muthukrishnan, Koci, Bryan, Wei, Haiyang, Fan, Jingsong, Levesque, Paul, Kwagh, Jae, Imredy, John, Zhai, Jin, Rogers, Marc, Humphries, Edward, Kirby, Robert, Stoelzle-Feix, Sonja, Brinkwirth, Nina, Rotordam, Maria Giustina, Becker, Nadine, Friis, Søren, Rapedius, Markus, Goetze, Tom A., Strassmaier, Tim, Okeyo, George, Kramer, James, Kuryshev, Yuri, Wu, Caiyun, Himmel, Herbert, Mirams, Gary R., Strauss, David G., Bardenet, Remi, Li, Zhihua

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Publisher Correction: Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells by Kramer, James, Himmel, Herbert M., Lindqvist, Anders, Stoelzle-Feix, Sonja, Chaudhary, Khuram W., Li, Dingzhou, Bohme, Georg Andrees, Bridgland-Taylor, Matthew, Hebeisen, Simon, Fan, Jingsong, Renganathan, Muthukrishnan, Imredy, John, Humphries, Edward S. A., Brinkwirth, Nina, Strassmaier, Tim, Ohtsuki, Atsushi, Danker, Timm, Vanoye, Carlos, Polonchuk, Liudmila, Fermini, Bernard, Pierson, Jennifer Beck, Gintant, Gary

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Ligand Gated Ion Channels on the Qube by Lindqvist, Anders, Løjkner, Lars D., Olsen, Hervør L., Friis, Søren, Jacobsen, Rasmus B., Sunesen, Morten R.

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Mutant huntingtin interacts with β-tubulin and disrupts vesicular transport and insulin secretion by Smith, Ruben, Bacos, Karl, Fedele, Valentina, Soulet, Denis, Walz, Helena A., Obermüller, Stefanie, Lindqvist, Anders, Björkqvist, Maria, Klein, Pontus, Önnerfjord, Patrik, Brundin, Patrik, Mulder, Hindrik, Li, Jia-Yi

“…Huntington's disease is a severe progressive neurodegenerative disorder caused by a CAG expansion in the IT15 gene, which encodes huntingtin. The disease…”
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Granule docking and cargo release in pancreatic beta-cells by Barg, Sebastian, Lindqvist, Anders, Obermüller, Stefanie

“…Biphasic insulin secretion is required for proper insulin action and is observed not only in vivo, but also in isolated pancreatic islets and even single…”
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