Search Results - "Lindpaintner, K"

Toward a roadmap in global biobanking for health by HARRIS, Jennifer R, BURTON, Paul, FORTIER, Isabel, HAINAUT, Pierre, HEWITT, Robert, KAYE, Jane, LITTON, Jan-Eric, METSPALU, Andres, OLLIER, Bill, PALMER, Lyle J, PALOTIE, Aarno, PASTERK, Markus, KNOPPERS, Bartha Maria, PEROLA, Markus, RIEGMAN, Peter Hj, OMMEN, Gert-Janvan, YUILLE, Martin, ZATLOUKAL, Kurt, LINDPAINTNER, Klaus, BLEDSOE, Marianna, BROOKES, Anthony J, BUDIN-LJØSNE, Isabelle, CHISHOLM, Rex, COX, David, DESCHENES, Mylène

“…Biobanks can have a pivotal role in elucidating disease etiology, translation, and advancing public health. However, meeting these challenges hinges on a…”
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Identification of a 52 kb deletion downstream of the SOST gene in patients with van Buchem disease by Balemans, W, Patel, N, Ebeling, M, Van Hul, E, Wuyts, W, Lacza, C, Dioszegi, M, Dikkers, F G, Hildering, P, Willems, P J, Verheij, J B G M, Lindpaintner, K, Vickery, B, Foernzler, D, Van Hul, W

“…Van Buchem disease is an autosomal recessive skeletal dysplasia characterised by generalised bone overgrowth, predominantly in the skull and mandible. Clinical…”
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Multi‐locus candidate gene polymorphisms and risk of myocardial infarction: a population‐based, prospective genetic analysis by ZEE, R. Y. L., COOK, N. R., CHENG, S., ERLICH, H. A., LINDPAINTNER, K., RIDKER, P. M.

“…Background: Polymorphisms in candidate genes related to lipid metabolism, thrombosis, hemostasis, cell‐matrix adhesion, and inflammation have been suggested…”
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Pseudoxanthoma elasticum : evaluation of diagnostic criteria based on molecular data by CHRISTEN-ZÄCH, S, HUBER, M, STRUK, B, LINDPAINTNER, K, MUNIER, F, PANIZZON, R. G, HOHL, D

“…Pseudoxanthoma elasticum (PXE) is a genetic disorder due to mutations in the gene encoding the transmembrane transporter protein adenosine triphosphate binding…”
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The Cardiac Renin-Angiotensin System: An Appraisal of Present Experimental and Clinical Evidence by Lindpaintner, Klaus, Ganten, Detlev

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Pharmacogenetics and the future of medical practice: conceptual considerations by LINDPAINTNER, K

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Proteomic analysis of the cerebrospinal fluid of patients with schizophrenia by Jiang, L, Lindpaintner, K, Li, H.-F, Gu, N.-F, Langen, H, He, L, Fountoulakis, M

“…We applied proteomics technologies to analyze the cerebrospinal fluid of patients with schizophrenia. Such an analysis can result in the identification of…”
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Mapping of Both Autosomal Recessive and Dominant Variants of Pseudoxanthoma Elasticum to Chromosome 16p13.1 by Struk, Berthold, Neldner, Kenneth H., Rao, Valluri S., St Jean, Pamela, Lindpaintner, Klaus

“…Pseudoxanthoma elasticum (PXE) is a classic inherited disorder of the elastic tissue characterized by progressive calcification of elastic fibers with a…”
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Mutation in the promoter region of the β-fibrinogen gene and the risk of future myocardial infarction, stroke and venous thrombosis by Blake, G.J., Schmitz, C., Lindpaintner, K., Ridker, P.M.

“…Aim Polymorphisms in the promoter region of the β-fibrinogen gene are associated with increased plasma fibrinogen levels. We investigated whether the…”
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Chromosomal mapping of two genetic loci associated with blood-pressure regulation in hereditary hypertensive rats by Hilbert, P, Lindpaintner, K, Beckmann, J. S, Serikawa, T, Soubrier, F, Dubay, C, Cartwright, P, Gouyon, B. De, Julier, C, Takahasi, S, Vincent, M, Ganten, D, Georges, M, Lathrop, G. M

“…The spontaneously hypertensive rat and the stroke-prone spontaneously hypertensive rat are useful models for human hypertension. In these strains hypertension…”
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Association of lipoprotein lipase S447X, apolipoprotein E exon 4, and apoC3 −455T>C polymorphisms on the susceptibility to diabetic nephropathy by Ng, MCY, Baum, L, So, W-Y, Lam, VKL, Wang, Y, Poon, E, Tomlinson, B, Cheng, S, Lindpaintner, K, Chan, JCN

“…Diabetic nephropathy (DN) is the leading cause of end‐stage renal disease. In DN patients, triglyceride (TG) level is elevated and lipoprotein lipase (LPL)…”
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Selecting SNPs in two-stage analysis of disease association data: a model-free approach by HOH, J., WILLE, A., ZEE, R., CHENG, S., REYNOLDS, R., LINDPAINTNER, K., OTT, J.

“…For large numbers of marker loci in a genomic scan for disease loci, we propose a novel 2-stage approach for linkage or association analysis. The two stages…”
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Genetics in drug discovery and development: challenge and promise of individualizing treatment in common complex diseases by Lindpaintner, K

“…An idea, once born, can never more be undone. Friedrich Duerrrenmatt, The physicists…”
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Lack of association between the SOST gene and bone mineral density in perimenopausal women: analysis of five polymorphisms by Balemans, W, Foernzler, D, Parsons, C, Ebeling, M, Thompson, A, Reid, D.M, Lindpaintner, K, Ralston, S.H, Van hul, W

“…Osteoporosis is a common disease characterized by a decrease in bone mass, architectural deterioration of the bone tissue, and an increased risk of fracture…”
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Genetics of interventional cardiology. Old principles, new frontiers by Lindpaintner, K

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Genetic linkage of the ACE gene to plasma angiotensin-converting enzyme activity but not to blood pressure : a quantitative trait locus confers identical complex phenotypes in human and rat hypertension by KREUTZ, R, HÜBNER, N, GANTEN, D, LINDPAINTNER, K

“…An allelic variant of the ACE gene has been found to be linked to plasma angiotensin-converting enzyme (ACE) activity in humans and has been implicated in the…”
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Lipid metabolism and occurrence of post‐percutaneous transluminal coronary angioplasty restenosis: role of cholesteryl ester transfer protein and paraoxonase/arylesterase by Zee, R. Y. L., Fernandez‐Otiz, A., Macaya, C., Pintor, E., Lindpaintner, K., Fernandez‐Cruz, A.

“…Plasma lipid metabolic and transfer processes have recently been suggested to play an important role in the development of early restenosis, a major…”
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Finding an obesity gene--a tale of mice and man by Lindpaintner, K

“…The term “complex disease” has been coined for conditions that arise from multifaceted interactions of environmental and heritable factors. It encompasses some…”
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A prospective evaluation of the interleukin-1 receptor antagonist intron 2 gene polymorphism and the risk of myocardial infarction by Zee, R Y, Lunze, K, Lindpaintner, K, Ridker, P M

“…While an interleukin-1 receptor antagonist gene polymorphism (IL1RN-VNTR) has recently been hypothesized to be a risk factor for coronary artery disease, no…”
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Local Stress, not Systemic Factors, Regulate Gene Expression of the Cardiac Renin-Angiotensin System in vivo: A Comprehensive Study of All Its Components in the Dog by Lee, Young-Ae, Liang, Chang-Seng, Lee, Min-Ae, Lindpaintner, Klaus

“…Cardiac hypertrophy is associated with altered expression of the components of the cardiac reninangiotensin system (RAS). While in vitro data suggest that…”
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