Search Results - "Lindner, Johanna M"
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Corticotropin-stimulated steroid profiles to predict shock development and mortality in sepsis: From the HYPRESS study
Published in Critical care (London, England) (07-11-2022)“…Abstract Rationale Steroid profiles in combination with a corticotropin stimulation test provide information about steroidogenesis and its functional reserves…”
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Biphenyl based stationary phases for improved selectivity in complex steroid assays
Published in Journal of pharmaceutical and biomedical analysis (05-08-2017)“…•Comprehensive steroid isotope-dilution LC–MS based assay.•Biphenyl based stationary phases are a powerful tool for steroid assays.•Zinc trifluoroacetate in…”
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Mechanistic basis for ubiquitin modulation of a protein energy landscape
Published in Proceedings of the National Academy of Sciences - PNAS (23-03-2021)“…Ubiquitin is a common posttranslational modification canonically associated with targeting proteins to the 26S proteasome for degradation and also plays a role…”
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Report from the HarmoSter study: impact of calibration on comparability of LC-MS/MS measurement of circulating cortisol, 17OH-progesterone and aldosterone
Published in Clinical chemistry and laboratory medicine (26-04-2022)“…Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is recommended for measuring circulating steroids. However, assays display technical heterogeneity…”
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Report from the HarmoSter study: different LC-MS/MS androstenedione, DHEAS and testosterone methods compare well; however, unifying calibration is a double-edged sword
Published in Clinical chemistry and laboratory medicine (27-05-2024)“…Current liquid chromatography-tandem mass spectrometry (LC-MS/MS) applications for circulating androgen measurements are technically diverse. Previously,…”
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Report from the HarmoSter study: inter-laboratory comparison of LC-MS/MS measurements of corticosterone, 11-deoxycortisol and cortisone
Published in Clinical chemistry and laboratory medicine (27-01-2023)“…Liquid chromatography-tandem mass spectrometry (LC-MS/MS) panels that include glucocorticoid-related steroids are increasingly used to characterize…”
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The dynamics of a serum steroid profile after stimulation with intravenous ACTH
Published in Journal of pharmaceutical and biomedical analysis (20-03-2018)“…•An extended steroid profile displays highly dynamic response to IV ACTH stimulation.•Far more pronounced relative increase of corticosterone compared to…”
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A semi-automated, isotope-dilution high-resolution mass spectrometry assay for therapeutic drug monitoring of antidepressants
Published in Clinical mass spectrometry (Del Mar, Calif.) (01-11-2019)“…Therapeutic drug monitoring (TDM) of antidepressants is important to ensure compliance and to rule out pharmacokinetic abnormalities. Therefore, reliable…”
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