Search Results - "Lindner, Christina"

Designed peptides as nanomolar cross-amyloid inhibitors acting via supramolecular nanofiber co-assembly by Taş, Karin, Volta, Beatrice Dalla, Lindner, Christina, El Bounkari, Omar, Hille, Kathleen, Tian, Yuan, Puig-Bosch, Xènia, Ballmann, Markus, Hornung, Simon, Ortner, Martin, Prem, Sophia, Meier, Laura, Rammes, Gerhard, Haslbeck, Martin, Weber, Christian, Megens, Remco T. A., Bernhagen, Jürgen, Kapurniotu, Aphrodite

“…Amyloid self-assembly is linked to numerous devastating cell-degenerative diseases. However, designing inhibitors of this pathogenic process remains a major…”
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Gamma secretase dependent release of the CD44 cytoplasmic tail upregulates IFI16 in cd44-/- tumor cells, MEFs and macrophages by Schultz, Kristin, Grieger Lindner, Christina, Li, Yong, Urbánek, Pavel, Ruschel, Anne, Minnich, Kerstin, Bruder, Dunja, Gereke, Marcus, Sechi, Antonio, Herrlich, Peter

“…The adhesion molecule and co-receptor of receptor tyrosine kinases, CD44, is expressed in all cells of the immune system, but also in numerous non-immune…”
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Inside-out Regulation of Ectodomain Cleavage of Cluster-of-Differentiation-44 (CD44) and of Neuregulin-1 Requires Substrate Dimerization by Hartmann, Monika, Parra, Liseth M., Ruschel, Anne, Lindner, Christina, Morrison, Helen, Herrlich, Andreas, Herrlich, Peter

“…Ectodomain shedding of transmembrane precursor proteins generates numerous life-essential molecules, such as epidermal growth factor receptor ligands. This…”
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Asc-1 regulates white versus beige adipocyte fate in a subcutaneous stromal cell population by Suwandhi, Lisa, Altun, Irem, Karlina, Ruth, Miok, Viktorian, Wiedemann, Tobias, Fischer, David, Walzthoeni, Thomas, Lindner, Christina, Böttcher, Anika, Heinzmann, Silke S., Israel, Andreas, Khalil, Ahmed Elagamy Mohamed Mahmoud, Braun, Alexander, Pramme-Steinwachs, Ines, Burtscher, Ingo, Schmitt-Kopplin, Philippe, Heinig, Matthias, Elsner, Martin, Lickert, Heiko, Theis, Fabian J., Ussar, Siegfried

“…Adipose tissue expansion, as seen in obesity, is often metabolically detrimental causing insulin resistance and the metabolic syndrome. However, white adipose…”
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Production of Amylases and Proteases by Bacillus caldolyticus from Food Industry Wastes by Thorsten Jamrath, Christina Lindner, Rakesh Bajpai, Milan K. Popović

“…Amylases and proteases are utilized in industrial processes such as starch liquefaction or as supplements for washing agents. For these applications it is…”
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Rapid On-Resin N-Formylation of Peptides as One-Pot Reaction by Kokollari, Agon, Werner, Marius, Lindner, Christina, Pham, Truc Lam, Thomas, Franziska

“…N-formylation is a common pre- and post-translational modification of the N-terminus or the lysine side chain of peptides and proteins that plays a role in the…”
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Thermostable WW-Domain Scaffold to Design Functional β‑Sheet Miniproteins by Lindner, Christina, Friemel, Anke, Schwegler, Niklas, Timmermann, Lisa, Pham, Truc Lam, Reusche, Vanessa, Kovermann, Michael, Thomas, Franziska

“…There has been a recent surge in the design of miniproteins for medicinal chemistry, biomaterial design, or synthetic biology. In particular, there is an…”
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Identification of novel functional mini-receptors by combinatorial screening of split-WW domains by Neitz, Hermann, Paul, Niels Benjamin, Häge, Florian R, Lindner, Christina, Graebner, Roman, Kovermann, Michael, Thomas, Franziska

“…β-Sheet motifs such as the WW domain are increasingly being explored as building blocks for synthetic biological applications. Since the sequence-structure…”
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VEGFR2 Signaling Prevents Colorectal Cancer Cell Senescence to Promote Tumorigenesis in Mice With Colitis by Foersch, Sebastian, Sperka, Tobias, Lindner, Christina, Taut, Astrid, Rudolph, Karl L, Breier, Georg, Boxberger, Frank, Rau, Tilman T, Hartmann, Arndt, Stürzl, Michael, Wittkopf, Nadine, Haep, Lisa, Wirtz, Stefan, Neurath, Markus F, Waldner, Maximilian J

“…Background & Aims Senescence prevents cellular transformation. We investigated whether vascular endothelial growth factor (VEGF) signaling via its receptor,…”
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A link between two tumorigenic proteins, CD44 and p21 WAF1 : CD44 increases phorbol ester‐induced expression of p21 WAF1 by stabilizing its mRNA and extending protein half‐life by Lindner, Christina, Urbánek, Pavel, Pavelka, Birgit, Hartmann, Monika, Herrlich, Peter

“…The cell surface glycoprotein CD44 enhances phorbol‐12‐myristate 13‐acetate (TPA)‐induced expression of p21 WAF1 by stabilizing its mRNA and enhancing the…”
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A link between two tumorigenic proteins, CD44 and p21WAF1: CD44 increases phorbol ester-induced expression of p21WAF1 by stabilizing its mRNA and extending protein half-life by Lindner, Christina, Urbánek, Pavel, Pavelka, Birgit, Hartmann, Monika, Herrlich, Peter

“…•We discovered that the glycoprotein CD44 enhances TPA-induced expression level of p21WAF1.•The increased p21 level is due to prolongation of the half-life of…”
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Stochastic resonance training reduces musculoskeletal symptoms in metal manufacturing workers: a controlled preventive intervention study by Burger, Christian, Schade, Volker, Lindner, Christina, Radlinger, Lorenz, Elfering, Achim

“…This study examined the effects of stochastic resonance whole-body vibration training on work-related musculoskeletal symptoms and accidents. Participants were…”
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"Is there a doctor on board?" - legal aspects of medical care in emergency situations during spare time by Lindner, Christina, Lindner, Gregor, Exadaktylos, Aristomenis K

“…Medical emergencies on international flights are not uncommon. In these situations the question often arises whether physicians are obliged to render first aid…”
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Treatment of patients with radioiodine refractory, differentiated thyroid carcinoma. A Consensus Statement by Lindner, Christina, Dierneder, J, Pall, G, Pirich, C, Hoffmann, M, Raderer, M, Becherer, A, Niederle, B, Lipp, R, Lind, P, Gallowitsch, H, Romeder, F, Virgolini, I

“…There is no clear standard therapy for patients with radioactive iodine (131I)-refractory locally advanced or metastatic differentiated thyroid cancer. The…”
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