Search Results - "Lindholm, Kristina"
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Deficiency of GDNF Receptor GFRα1 in Alzheimer's Neurons Results in Neuronal Death
Published in The Journal of neuroscience (24-09-2014)“…We have recently developed aged cortical neuron cultures from autopsied human brains with Alzheimer's disease (AD). During the culturing process, we found that…”
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Amyloid β Peptide Load Is Correlated with Increased β-Secretase Activity in Sporadic Alzheimer's Disease Patients
Published in Proceedings of the National Academy of Sciences - PNAS (09-03-2004)“…Whether elevated β-secretase (BACE) activity is related to plaque formation or amyloid β peptide (Aβ) production in Alzheimer's disease (AD) brains remains…”
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Target Depletion of Distinct Tumor Necrosis Factor Receptor Subtypes Reveals Hippocampal Neuron Death and Survival through Different Signal Transduction Pathways
Published in The Journal of neuroscience (15-04-2002)“…Tumor necrosis factor receptor-I (TNFRI) and TNFRII are two TNFR subtypes in the immune system, but their roles in the brain remain unclear. Here we present a…”
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Distinct destructive signal pathways of neuronal death in Alzheimer's disease
Published in Trends in molecular medicine (01-12-2006)“…Abundant neuron loss is a major feature of Alzheimer's disease (AD). Hypotheses for this loss include abnormal amyloid precursor protein processing (i.e…”
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Disruption of specific GDNF receptor subtype signaling impairs cortical neuronal survival in Alzheimer’s brains
Published in Molecular neurodegeneration (07-02-2012)“…[...] the survival effects of GDNF- receptor pathway in ND neurons appear to be mediated by the specific signal transduction pathway…”
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Isolation of Living Neurons from Human Elderly Brains Using the Immunomagnetic Sorting DNA-Linker System
Published in The American journal of pathology (01-11-2002)“…Isolation and culture of mature neurons from affected brain regions during diseased states provide a well-suited in vitro model system to study age-related…”
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Deletion of tumor necrosis factor death receptor inhibits amyloid β generation and prevents learning and memory deficits in Alzheimer's mice
Published in The Journal of cell biology (27-08-2007)“…The tumor necrosis factor type 1 death receptor (TNFR1) contributes to apoptosis. TNFR1, a subgroup of the TNFR superfamily, contains a cytoplasmic death…”
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Deficiency of GDNF Receptor GFR alpha 1 in Alzheimer's Neurons Results in Neuronal Death
Published in The Journal of neuroscience (24-09-2014)“…We have recently developed aged cortical neuron cultures from autopsied human brains with Alzheimer's disease (AD). During the culturing process, we found that…”
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Elevated β-secretase expression and enzymatic activity detected in sporadic Alzheimer disease
Published in Nature medicine (01-01-2003)Get full text
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Tumor necrosis factor death receptor signaling cascade is required for amyloid-beta protein-induced neuron death
Published in The Journal of neuroscience (18-02-2004)“…Tumor necrosis factor type I receptor (TNFRI), a death receptor, mediates apoptosis and plays a crucial role in the interaction between the nervous and immune…”
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Crisis Communication as a Multilevel Game: The Muhammad Cartoons from a Crisis Diplomacy Perspective
Published in The international journal of press/politics (01-04-2011)“…The Muhammad cartoon crisis in 2005 provides an illustrative example of how crises travel across geographical boundaries, in this case, from a national…”
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Deletion of tumor necrosis factor death receptor inhibits amyloid [beta] generation and prevents learning and memory deficits in Alzheimer's mice
Published in The Journal of cell biology (27-08-2007)“…The tumor necrosis factor type 1 death receptor (TNFR1) contributes to apoptosis. TNFR1, a subgroup of the TNFR superfamily, contains a cytoplasmic death…”
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P3-299 TNF death receptor signaling cascade is required for amyloid-β protein induced neuron death
Published in Neurobiology of aging (01-07-2004)Get full text
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The temporal localization of frame-shift ubiquitin-B and amyloid precursor protein, and complement proteins in the brain of non-demented control patients with increasing Alzheimer's disease pathology
Published in Neuroscience letters (04-09-2003)“…Transcriptional misreading of dinucleotide repeats that generates deletions in RNA and produces frame-shift proteins with loss of function has been reported in…”
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Elevated [beta]-secretase expression and enzymatic activity detected in sporadic Alzheimer disease
Published in Nature medicine (01-01-2003)Get full text
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Ssu Och könspolitikens gränser 1970- 2000 : Diskussionerna Om Kvinnorepresentation i Sveriges Socialdemokratiska Ungdomsförbund
Published 01-01-2008“…Politiska ungdomsförbund är viktiga arenor där unga människor diskuterar och formulerar frågor som kan bli en del av den politiska dagordningen. Sättet som en…”
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Dissertation -
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Tumor Necrosis Factor Death Receptor Signaling Cascade Is Required for Amyloid-{beta} Protein-Induced Neuron Death
Published in The Journal of neuroscience (18-02-2004)Get full text
Journal Article