Search Results - "Lindhe, Örjan"

[18F]Fluoroacetate is not a functional analogue of [11C]acetate in normal physiology by Lindhe, Örjan, Sun, Aijun, Ulin, Johan, Rahman, Obaidur, Långström, Bengt, Sörensen, Jens

“…Purpose [ 11 C]Acetate (C-AC) is a general PET tracer of cellular carbon flux and useful for clinical imaging in heart disease as well as prostate cancer and…”
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(18)F-labelled metomidate analogues as adrenocortical imaging agents by Erlandsson, Maria, Karimi, Farhad, Lindhe, Orjan, Långström, Bengt

“…Two- and one-step syntheses of (18)F-labelled analogues of metomidate, such as 2-[(18)F]fluoroethyl 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate (1),…”
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Restricted Cortical and Amygdaloid Removal of Vesicular Glutamate Transporter 2 in Preadolescent Mice Impacts Dopaminergic Activity and Neuronal Circuitry of Higher Brain Function by Wallen-Mackenzie, Asa, Nordenankar, Karin, Fejgin, Kim, Lagerstrom, Malin C, Emilsson, Lina, Fredriksson, Robert, Wass, Caroline, Andersson, Daniel, Egecioglu, Emil, Andersson, My, Strandberg, Joakim, Lindhe, Orjan, Schioth, Helgi B, Chergui, Karima, Hanse, Eric, Langstrom, Bengt, Fredriksson, Anders, Svensson, Lennart, Roman, Erika, Kullander, Klas

“…A major challenge in neuroscience is to resolve the connection between gene functionality, neuronal circuits, and behavior. Most, if not all, neuronal circuits…”
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Species differences in 3-methylsulphonyl-DDE bioactivation by adrenocortical tissue by Lindström, Veronica, Brandt, Ingvar, Lindhe, Örjan

“…The CYP11B1-activated adrenocortical toxicant 3-methylsulphonyl-DDE (3-MeSO 2 -DDE) is proposed as a lead compound for an improved chemotherapy for…”
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Assessing the Preanalytical Variability of Plasma and Cerebrospinal Fluid Processing and Its Effects on Inflammation-Related Protein Biomarkers by Huang, Jesse, Khademi, Mohsen, Lindhe, Örjan, Jönsson, Gunn, Piehl, Fredrik, Olsson, Tomas, Kockum, Ingrid

“…Proteomics studies are important for the discovery of new biomarkers as clinical tools for diagnosis and disease monitoring. However, preanalytical variations…”
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Species Differences in Blood-Brain Barrier Transport of Three Positron Emission Tomography Radioligands with Emphasis on P-Glycoprotein Transport by Syvänen, Stina, Lindhe, Orjan, Palner, Mikael, Kornum, Birgitte R, Rahman, Obaidur, Långström, Bengt, Knudsen, Gitte M, Hammarlund-Udenaes, Margareta

“…Species differences occur in the brain concentrations of drugs, but the reasons for these differences are not yet apparent. This study was designed to compare…”
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Shrunken Pore Syndrome Is Associated With Increased Levels of Atherosclerosis-Promoting Proteins by Almén, Markus Sällman, Björk, Jonas, Nyman, Ulf, Lindström, Veronica, Jonsson, Magnus, Abrahamson, Magnus, Vestergren, AnnaLotta Schiller, Lindhe, Örjan, Franklin, Gary, Christensson, Anders, Grubb, Anders

“…Shrunken pore syndrome (SPS), originally defined by cystatin C-based estimated glomerular filtration rate (eGFR ) being less than 60% of creatinine-based…”
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[11C]Metomidate Positron Emission Tomography of Adrenocortical Tumors in Correlation with Histopathological Findings by Hennings, Joakim, Lindhe, Örjan, Bergström, Mats, Långström, Bengt, Sundin, Anders, Hellman, Per

“…Context: Adrenal incidentalomas are common findings necessitating extensive laboratory work-up and repetitive radiological examinations. Positron emission…”
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Cytochrome P450-Catalyzed Binding of 3-Methylsulfonyl-DDE and o,p′-DDD in Human Adrenal Zona Fasciculata/Reticularis by Lindhe, Örjan, Skogseid, Britt, Brandt, Ingvar

“…3-Methylsulfonyl-2,2′-bis(4-chlorophenyl)-1,1′-dichloroethene (MeSO2-DDE) is a potent, tissue-specific toxicant that induces necrosis of the adrenal zona…”
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Target cells for cytochrome P450-catalysed irreversible binding of 7,12-dimethylbenz[a]anthracene (DMBA) in rodent adrenal glands by LINDHE, Örjan, GRANBERG, Lizette, BRANDT, Ingvar

“…7,12-Dimethylbenz[a]anthracene (DMBA) is an adrenocorticolytic agent that causes apoplexy (haemorrhage) and massive necrosis in the adrenal cortex in rat…”
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Inflammation-related plasma and CSF biomarkers for multiple sclerosis by Huang, Jesse, Khademia, Mohsen, Fugger, Lars, Lindhe, Örjan, Novakova, Lenka, Axelsson, Markus, Malmeström, Clas, Constantinescu, Clara, Lycke, Jan, Piehl, Fredrik, Olsson, Tomas, Kockum, Ingrid

“…Effective biomarkers for multiple sclerosis diagnosis, assessment of prognosis, and treatment responses, in particular those measurable in blood, are largely…”
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Preparation and evaluation of (68)Ga-DOTA-hEGF for visualization of EGFR expression in malignant tumors by Velikyan, Irina, Sundberg, Asa Liljegren, Lindhe, Orjan, Höglund, A Urban, Eriksson, Olof, Werner, Eva, Carlsson, Jorgen, Bergström, Mats, Långström, Bengt, Tolmachev, Vladimir

“…Detection of epidermal growth factor receptor (EGFR) overexpression in many carcinomas provides important diagnostic information, which can influence patient…”
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Irreversible binding of o, p′-DDD in interrenal cells of Atlantic cod ( Gadus morhua) by Lindhe, Örjan, Brandt, Ingvar, Schou Christiansen, Jørgen, Ingebrigtsen, Kristian

“…Precision-cut tissue slices of the anterior kidney from Atlantic cod ( Gadus morhua) were prepared with a Krumdieck tissue slicer and exposed to…”
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Preparation and evaluation of a 68Ga-labeled RGD-containing octapeptide for noninvasive imaging of angiogenesis: biodistribution in non-human primate by Velikyan, Irina, Lindhe, Örjan

“…Monitoring general disease marker such as angiogenesis may contribute to the development of personalized medicine and improve therapy outcome. Readily…”
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Preparation and evaluation of a 68 Ga-labeled RGD-containing octapeptide for noninvasive imaging of angiogenesis: biodistribution in non-human primate by Velikyan, Irina, Lindhe, Örjan

“…Monitoring general disease marker such as angiogenesis may contribute to the development of personalized medicine and improve therapy outcome. Readily…”
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Cytochrome P450-Catalyzed Binding of 3-Methylsulfonyl-DDE and o,p′-DDD in Human Adrenal Zona Fasciculata/Reticularis by Lindhe, örjan, Skogseid, Britt, Brandt, Ingvar

“…3-Methylsulfonyl-2,2′-bis(4-chlorophenyl)-1,1′-dichloroethene (MeSO2-DDE) is a potent, tissue-specific toxicant that induces necrosis of the adrenal zona…”
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Synthesis and biological evaluation of [carboxyl-11C]eprosartan by Åberg, Ola, Lindhe, Örjan, Hall, Håkan, Hellman, Per, Kihlberg, Tor, Långström, Bengt

“…Essential hypertension occurs in approximately 25% of the adult population and one cause of hypertension is primary aldosteronism. Targeting the angiotensin II…”
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Synthesis of two potential NK1-receptor ligands using [1-11C]ethyl iodide and [1-11C]propyl iodide and initial PET-imaging by Syvänen, Stina, Eriksson, Jonas, Genchel, Tove, Lindhe, Orjan, Antoni, Gunnar, Långström, Bengt

“…The previously validated NK1-receptor ligand [O-methyl-11C]GR205171 binds with a high affinity to the NK1-receptor and displays a slow dissociation from the…”
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In vitro imaging techniques in neurodegenerative diseases by Långström, Bengt, Andrén, Per E, Lindhe, Orjan, Svedberg, Marie, Hall, Håkan

“…Neurodegeneration induces various changes in the brain, changes that may be investigated using neuroimaging techniques. The in vivo techniques are useful for…”
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Abstract 2430: PET imaging of c-Met expression in non-human primates using [18F]AH113804 by Lindhe, Örjan, Thibblin, Alf, Antoni, Gunnar, Indrevoll, Bård, Evans, Paul, Morrison, Matthew, Dalsgaard, Grethe Tang, Johannesen, Edvin

“…Abstract [18F]AH113804 is a peptide based molecular imaging agent with high affinity for the human c-Met receptor. The objective of this study was to…”
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