Search Results - "Lindgren, Hanna S"

l-DOPA-induced dopamine efflux in the striatum and the substantia nigra in a rat model of Parkinson's disease: temporal and quantitative relationship to the expression of dyskinesia by Lindgren, Hanna S, Andersson, Daniel R, Lagerkvist, Sören, Nissbrandt, Hans, Cenci, M. Angela

“…J. Neurochem. (2010) 112, 1465-1476. l-DOPA-induced dyskinesia in Parkinson's disease is associated with large increases in brain dopamine (DA) levels…”
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Impaired cognitive and motor function are coincident with l-DOPA-induced dyskinesia in a model of Parkinson’s disease by Lelos, Mariah J., Murphy, Ellen M., Lindgren, Hanna S., Dunnett, Stephen B., Lane, Emma L.

“…Dopamine transmission has been implicated in motor and cognitive function. In Parkinson’s disease (PD), dopamine replacement using the precursor drug l -DOPA…”
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Vascular endothelial growth factor is upregulated by l-dopa in the parkinsonian brain: implications for the development of dyskinesia by Ohlin, K. Elisabet, Francardo, Veronica, Lindgren, Hanna S., Sillivan, Stephanie E., O'Sullivan, Sean S., Luksik, Andrew S., Vassoler, Fair M., Lees, Andrew J., Konradi, Christine, Cenci, M. Angela

“…Angiogenesis and increased permeability of the blood-brain barrier have been reported to occur in animal models of Parkinson's disease and l-dopa-induced…”
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Rodent models of impulsive–compulsive behaviors in Parkinson's disease: How far have we reached? by Cenci, M. Angela, Francardo, Veronica, O'Sullivan, Sean S, Lindgren, Hanna S

“…Abstract There is increasing awareness that the medications used to treat the motor symptoms of Parkinson's disease (PD) contribute to the development of…”
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Role of striatal l‐DOPA in the production of dyskinesia in 6‐hydroxydopamine lesioned rats by Carta, Manolo, Lindgren, Hanna S., Lundblad, Martin, Stancampiano, Roberto, Fadda, Fabio, Cenci, M. A.

“…We explored possible differences in the peripheral and central pharmacokinetics of l‐DOPA as a basis for individual variation in the liability to dyskinesia…”
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Endothelial Proliferation and Increased Blood-Brain Barrier Permeability in the Basal Ganglia in a Rat Model of 3,4-Dihydroxyphenyl-L-Alanine-Induced Dyskinesia by Westin, Jenny E, Lindgren, Hanna S, Gardi, Jonathan, Nyengaard, Jens Randel, Brundin, Patrik, Mohapel, Paul, Cenci, M. Angela

“…3,4-Dihydroxyphenyl-L-alanine (L-DOPA)-induced dyskinesia is associated with molecular and synaptic plasticity in the basal ganglia, but the occurrence of…”
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l -DOPA dosage is critically involved in dyskinesia via loss of synaptic depotentiation by Picconi, Barbara, Paillé, Vincent, Ghiglieri, Veronica, Bagetta, Vincenza, Barone, Ilaria, Lindgren, Hanna S, Bernardi, Giorgio, Angela Cenci, M, Calabresi, Paolo

“…Abstract The emergence of levodopa ( l -DOPA)-induced dyskinesia and motor fluctuations represents a major clinical problem in Parkinson's disease (PD). While…”
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Cognitive dysfunction and depression in Parkinson's disease: what can be learned from rodent models? by Lindgren, Hanna S., Dunnett, Stephen B.

“…Parkinson’s disease (PD) has for decades been considered a pure motor disorder and its cardinal motor symptoms have been attributed to the loss of dopaminergic…”
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Do alpha-synuclein vector injections provide a better model of Parkinson's disease than the classic 6-hydroxydopamine model? by Lindgren, Hanna S., Lelos, Mariah J., Dunnett, Stephen B.

“…Improvements in modelling Parkinson's disease in rodents contribute to the advancement of scientific knowledge and open innumerable pathways for the…”
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Lesions of the dorsomedial striatum impair formation of attentional set in rats by Lindgren, Hanna S., Wickens, Robin, Tait, David S., Brown, Verity J., Dunnett, Stephen B.

“…Behavioural flexibility refers to the ability to rapidly adapt to novel situations and it has been suggested that the frontal lobe and basal ganglia are…”
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Differential Involvement of D1 and D2 Dopamine Receptors in L-DOPA-Induced Angiogenic Activity in a Rat Model of Parkinson's Disease by LINDGREN, Hanna S, ELISABET OHLIN, K, CENTI, M. Angela

“…Angiogenesis occurs in the brains of Parkinson's disease patients, but the effects of dopamine replacement therapy on this process have not been examined…”
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Nigral 6-hydroxydopamine lesion impairs performance in a lateralised choice reaction time task—Impact of training and task parameters by Lindgren, Hanna S., Klein, Alexander, Dunnett, Stephen B.

“…•Nigral 6-OHDA lesion impairs the performance in a choice reaction time task.•Same pattern of deficits as after striatal and bundle 6-OHDA…”
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The effect of additional noradrenergic and serotonergic depletion on a lateralised choice reaction time task in rats with nigral 6-OHDA lesions by Lindgren, Hanna S., Demirbugen, Merve, Bergqvist, Filip, Lane, Emma L., Dunnett, Stephen B.

“…Parkinson's disease (PD) patients often suffer from visuospatial deficits, which have been considered a disruption of the representation of external space. The…”
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The “motor complication syndrome” in rats with 6-OHDA lesions treated chronically with l-DOPA: Relation to dose and route of administration by Lindgren, Hanna S., Rylander, Daniella, Ohlin, K. Elisabet, Lundblad, Martin, Cenci, M. Angela

“…l-DOPA-induced motor complications can be modelled in rats with 6-hydroxydopamine (6-OHDA) lesions by chronic injections of l-DOPA. We have compared the…”
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The effect of additional noradrenergic and serotonergic depletion on lateralised choice reaction time task in rats with nigral 6-OHDA lesions by Demirbugen, Merve, Lindgren, Hanna S., Lane, Emma L.

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Putaminal upregulation of FosB/ΔFosB-like immunoreactivity in Parkinson's disease patients with dyskinesia by Lindgren, H S, Rylander, D, Iderberg, H, Andersson, M, O'Sullivan, S S, Williams, D R, Lees, A J, Cenci, M A

“…The transcription factor ΔFosB is a mediator of maladaptive neuroplasticity in animal models of Parkinson's disease (PD) and L-DOPA-induced dyskinesia. Using…”
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Role of striatall-DOPA in the production of dyskinesia in 6-hydroxydopamine lesioned rats by Carta, Manolo, Lindgren, Hanna S, Lundblad, Martin, Stancampiano, Roberto, Fadda, Fabio, Cenci, M A

“…We explored possible differences in the peripheral and central pharmacokinetics ofl-DOPA as a basis for individual variation in the liability to dyskinesia…”
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