Search Results - "Lindgren, Arne G."

Human monocyte subtype expression of neuroinflammation- and regeneration-related genes is linked to age and sex by Tampé, Juliane F, Monni, Emanuela, Palma-Tortosa, Sara, Brogårdh, Emil, Böiers, Charlotta, Lindgren, Arne G, Kokaia, Zaal

“…Aging profoundly affects the immune system leading to an increased propensity for inflammation. Age-related dysregulation of immune cells is implicated in the…”
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Outcome after acute ischemic stroke is linked to sex-specific lesion patterns by Bonkhoff, Anna K., Schirmer, Markus D., Bretzner, Martin, Hong, Sungmin, Regenhardt, Robert W., Brudfors, Mikael, Donahue, Kathleen L., Nardin, Marco J., Dalca, Adrian V., Giese, Anne-Katrin, Etherton, Mark R., Hancock, Brandon L., Mocking, Steven J. T., McIntosh, Elissa C., Attia, John, Benavente, Oscar R., Bevan, Stephen, Cole, John W., Donatti, Amanda, Griessenauer, Christoph J., Heitsch, Laura, Holmegaard, Lukas, Jood, Katarina, Jimenez-Conde, Jordi, Kittner, Steven J., Lemmens, Robin, Levi, Christopher R., McDonough, Caitrin W., Meschia, James F., Phuah, Chia-Ling, Rolfs, Arndt, Ropele, Stefan, Rosand, Jonathan, Roquer, Jaume, Rundek, Tatjana, Sacco, Ralph L., Schmidt, Reinhold, Sharma, Pankaj, Slowik, Agnieszka, Söderholm, Martin, Sousa, Alessandro, Stanne, Tara M., Strbian, Daniel, Tatlisumak, Turgut, Thijs, Vincent, Vagal, Achala, Wasselius, Johan, Woo, Daniel, Zand, Ramin, McArdle, Patrick F., Worrall, Bradford B., Jern, Christina, Lindgren, Arne G., Maguire, Jane, Bzdok, Danilo, Wu, Ona, Rost, Natalia S.

“…Acute ischemic stroke affects men and women differently. In particular, women are often reported to experience higher acute stroke severity than men. We…”
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Detection of Unilateral Arm Paresis after Stroke by Wearable Accelerometers and Machine Learning by Wasselius, Johan, Lyckegård Finn, Eric, Persson, Emma, Ericson, Petter, Brogårdh, Christina, Lindgren, Arne G., Ullberg, Teresa, Åström, Kalle

“…Recent advances in stroke treatment have provided effective tools to successfully treat ischemic stroke, but still a majority of patients are not treated due…”
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Causes and predictors of death in cerebral venous thrombosis by CANHAO, Patricia, FERRO, José M, LINDGREN, Arne G, BOUSSER, Marie-Germaine, STAM, Jan, BARINAGARREMENTERIA, Fernando

“…The causes of death of patients with cerebral venous thrombosis (CVT) have not been systematically addressed in previous studies. We aimed to analyze the…”
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Spatiotemporal sphingosine-1-phosphate receptor 3 expression within the cerebral vasculature after ischemic stroke by Matuskova, Hana, Porschen, Lisa T., Matthes, Frank, Lindgren, Arne G., Petzold, Gabor C., Meissner, Anja

“…Sphingosine-1-phosphate receptors (S1PRs) are promising therapeutic targets in cardiovascular disease, including ischemic stroke. However, important…”
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A novel scatterplot-based method to detect copy number variation (CNV) by Qiao, Jia-Lu, Levinson, Rebecca T, Chen, Bowang, Engelter, Stefan T, Erhart, Philipp, Gaynor, Brady J, McArdle, Patrick F, Schlicht, Kristina, Krawczak, Michael, Stenman, Martin, Lindgren, Arne G, Cole, John W, Grond-Ginsbach, Caspar

“…Most methods to detect copy number variation (CNV) have high false positive rates, especially for small CNVs and in real-life samples from clinical studies. In…”
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Excessive White Matter Hyperintensity Increases Susceptibility to Poor Functional Outcomes After Acute Ischemic Stroke by Hong, Sungmin, Giese, Anne-Katrin, Schirmer, Markus D, Bonkhoff, Anna K, Bretzner, Martin, Rist, Pamela, Dalca, Adrian V, Regenhardt, Robert W, Etherton, Mark R, Donahue, Kathleen L, Nardin, Marco, Mocking, Steven J T, McIntosh, Elissa C, Attia, John, Benavente, Oscar R, Cole, John W, Donatti, Amanda, Griessenauer, Christoph J, Heitsch, Laura, Holmegaard, Lukas, Jood, Katarina, Jimenez-Conde, Jordi, Roquer, Jaume, Kittner, Steven J, Lemmens, Robin, Levi, Christopher R, McDonough, Caitrin W, Meschia, James F, Phuah, Chia-Ling, Rolfs, Arndt, Ropele, Stefan, Rosand, Jonathan, Rundek, Tatjana, Sacco, Ralph L, Schmidt, Reinhold, Enzinger, Christian, Sharma, Pankaj, Slowik, Agnieszka, Sousa, Alessandro, Stanne, Tara M, Strbian, Daniel, Tatlisumak, Turgut, Thijs, Vincent, Vagal, Achala, Wasselius, Johan, Woo, Daniel, Zand, Ramin, McArdle, Patrick F, Worrall, Bradford B, Wu, Ona, Jern, Christina, Lindgren, Arne G, Maguire, Jane, Tomppo, Liisa, Golland, Polina, Rost, Natalia S

“…To personalize the prognostication of post-stroke outcome using MRI-detected cerebrovascular pathology, we sought to investigate the association between the…”
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A stroke gene panel for whole-exome sequencing by Ilinca, Andreea, Samuelsson, Sofie, Piccinelli, Paul, Soller, Maria, Kristoffersson, Ulf, Lindgren, Arne G.

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Survival, causes of death and recurrence up to 3 years after stroke: A population‐based study by Aked, Joseph, Delavaran, Hossein, Lindgren, Arne G.

“…Background and purpose Up‐to‐date population‐based information about long‐term survival, causes of death and recurrence after stroke is needed. Methods Four…”
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Diagnosing Monogenic Stroke at Younger Age by Ilinca, Andreea, Kafantari, Efthymia, Wallenius, Joel, Kristoffersson, Ulf, Englund, Elisabet, Puschmann, Andreas, Lindgren, Arne G.

“…BACKGROUND: An increasing number of monogenic conditions underlying stroke are being identified. We explored the possibilities of increasing the diagnostic…”
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New generation genetic testing entering the clinic by Gorcenco, Sorina, Ilinca, Andreea, Almasoudi, Wejdan, Kafantari, Efthymia, Lindgren, Arne G., Puschmann, Andreas

“…New generation sequencing (NGS) genetic testing is a powerful diagnostic tool and is increasingly used in the clinical workup of patients, especially in…”
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Factor XIa inhibition with asundexian after acute non-cardioembolic ischaemic stroke (PACIFIC-Stroke): an international, randomised, double-blind, placebo-controlled, phase 2b trial by Shoamanesh, Ashkan, Mundl, Hardi, Smith, Eric E, Masjuan, Jaime, Milanov, Ivan, Hirano, Teruyuki, Agafina, Alina, Campbell, Bruce, Caso, Valeria, Mas, Jean-Louis, Dong, Qiang, Turcani, Peter, Christensen, Hanne, Ferro, Jose M, Veltkamp, Roland, Mikulik, Robert, De Marchis, Gian Marco, Robinson, Thompson, Lemmens, Robin, Stepien, Adam, Greisenegger, Stefan, Roine, Risto, Csiba, Laszlo, Khatri, Pooja, Coutinho, Jonathan, Lindgren, Arne G, Demchuk, Andrew M, Colorado, Pablo, Kirsch, Bodo, Neumann, Christoph, Heenan, Laura, Xu, Lizhen, Connolly, Stuart J, Hart, Robert G

“…Asundexian (Bayer AG, Leverkusen, Germany), an oral small molecule factor XIa (FXIa) inhibitor, might prevent thrombosis without increasing bleeding…”
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Using Human Genetics to Understand Mechanisms in Ischemic Stroke Outcome: From Early Brain Injury to Long-Term Recovery by Lee, Jin-Moo, Fernandez-Cadenas, Israel, Lindgren, Arne G.

“…There is a critical need to elucidate molecular mechanisms underlying brain injury, repair, and recovery following ischemic stroke—a global health problem with…”
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A stroke gene panel for whole-exome sequencing by Ilinca, Andreea, Samuelsson, Sofie, Piccinelli, Paul, Soller, Maria, Kristoffersson, Ulf, Lindgren, Arne G

“…Extensive analyses of known monogenic causes of stroke by whole-exome/genome sequencing are technically possible today. We here aimed to compile a…”
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Pericyte Microvesicles as Plasma Biomarkers Reflecting Brain Microvascular Signaling in Patients With Acute Ischemic Stroke by Gaceb, Abderahim, Roupé, Linnea, Enström, Andreas, Almasoudi, Wejdan, Carlsson, Robert, Lindgren, Arne G, Paul, Gesine

“…Blood-based biomarkers have the potential to reflect cerebrovascular signaling after microvascular injury; yet, the detection of cell-specific signaling has…”
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Mosaic Loss of Chromosome Y Is Associated With Functional Outcome After Ischemic Stroke by Dorvall, Malin, Pedersen, Annie, Dumanski, Jan P., Söderholm, Martin, Lindgren, Arne G., Stanne, Tara M., Jern, Christina

“…Mosaic loss of chromosome Y (LOY) is associated with cardiovascular and neurodegenerative diseases in men, and genetic predisposition to LOY is associated with…”
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Updated Stroke Gene Panels: Rapid evolution of knowledge on monogenic causes of stroke by Ilinca, Andreea, Puschmann, Andreas, Putaala, Jukka, de Leeuw, Frank Erik, Cole, John, Kittner, Stephen, Kristoffersson, Ulf, Lindgren, Arne G

“…This article updates our previous Stroke Gene Panels (SGP) from 2017. Online Mendelian Inheritance in Man and PubMed were searched. We divided detected genes…”
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Andexanet for Factor Xa Inhibitor–Associated Acute Intracerebral Hemorrhage by Connolly, Stuart J., Sharma, Mukul, Cohen, Alexander T., Demchuk, Andrew M., Członkowska, Anna, Lindgren, Arne G., Molina, Carlos A., Bereczki, Daniel, Toni, Danilo, Seiffge, David J., Tanne, David, Sandset, Else Charlotte, Tsivgoulis, Georgios, Christensen, Hanne, Beyer-Westendorf, Jan, Coutinho, Jonathan M., Crowther, Mark, Verhamme, Peter, Amarenco, Pierre, Roine, Risto O., Mikulik, Robert, Lemmens, Robin, Veltkamp, Roland, Middeldorp, Saskia, Robinson, Thompson G., Milling, Truman John, Tedim-Cruz, Vitor, Lang, Wilfried, Himmelmann, Anders, Ladenvall, Per, Knutsson, Mikael, Ekholm, Ella, Law, Andrew, Taylor, Amanda, Karyakina, Tetyana, Xu, Lizhen, Tsiplova, Kate, Poli, Sven, Kallmünzer, Bernd, Gumbinger, Christoph, Shoamanesh, Ashkan

“…The factor Xa inhibitor reversal agent andexanet reduced expansion of intracerebral hemorrhages caused by factor Xa inhibitors but resulted in more thrombotic…”
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ESO Guideline on covert cerebral small vessel disease by Wardlaw, Joanna M, Debette, Stephanie, Jokinen, Hanna, De Leeuw, Frank-Erik, Pantoni, Leonardo, Chabriat, Hugues, Staals, Julie, Doubal, Fergus, Rudilosso, Salvatore, Eppinger, Sebastian, Schilling, Sabrina, Ornello, Raffaele, Enzinger, Christian, Cordonnier, Charlotte, Taylor-Rowan, Martin, Lindgren, Arne G

“…‘Covert’ cerebral small vessel disease (ccSVD) is common on neuroimaging in persons without overt neurological manifestations, and increases the risk of future…”
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Domain-Specific Outcomes for Stroke Clinical Trials: What the Modified Rankin Isn't Ranking by Braun, Robynne G., Heitsch, Laura, Cole, John W., Lindgren, Arne G., de Havenon, Adam, Dude, Jason A., Lohse, Keith R., Cramer, Steven C., Worrall, Bradford B.

“…Global outcome measures that are widely used in stroke clinical trials, such as the modified Rankin Scale (mRS), lack sufficient detail to detect changes…”
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