Search Results - "Lindert, S."
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Optimising primary molecular profiling in non-small cell lung cancer
Published in PloS one (31-07-2024)“…Molecular profiling of NSCLC is essential for optimising treatment decisions, but often incomplete. We assessed the efficacy of protocolised molecular…”
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Nationwide differences in cytology fixation and processing methods and their impact on interlaboratory variation in PD-L1 positivity
Published in Virchows Archiv : an international journal of pathology (01-04-2023)“…Programmed death ligand-1 (PD-L1) immunostaining, which aids clinicians in decision-making on immunotherapy for non-small cell lung cancer (NSCLC) patients, is…”
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Toxicity-specific peripheral blood T and B cell dynamics in anti-PD-1 and combined immune checkpoint inhibition
Published in Cancer Immunology, Immunotherapy (01-12-2023)“…Immune checkpoint inhibitors (ICI) have revolutionized the treatment landscape of advanced malignancies, but come with a diverse spectrum of immune-related…”
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Individual treatment effect estimation in the presence of unobserved confounding using proxies: a cohort study in stage III non-small cell lung cancer
Published in Scientific reports (07-04-2022)“…Randomized Controlled Trials (RCT) are the gold standard for estimating treatment effects but some important situations in cancer care require treatment effect…”
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Hematologic malignancies following immune checkpoint inhibition for solid tumors
Published in Cancer Immunology, Immunotherapy (01-01-2023)“…Immune checkpoint inhibition (ICI) can induce durable responses in patients with advanced malignancies. Three cases of hematological neoplasia following ICI…”
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Open communication between patients and relatives about illness & death in advanced cancer—results of the eQuiPe Study
Published in Supportive care in cancer (01-04-2024)“…Objective To assess the degree of openness of communication about illness and death between patients with advanced cancer and their relatives during the last…”
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Non-Small-Cell Lung Cancer Patients with a High Predicted Risk of Irradical Resection: Can Chemoradiotherapy Offer Similar Survival?
Published in Annals of surgical oncology (01-03-2022)“…Purpose Irradical resection of non-small-cell lung cancer (NSCLC) is a detrimental prognostic factor. Recently, Rasing et al. presented an internationally…”
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Treatment decision‐making and the added value of the general practitioner: A qualitative exploration of cancer patients' perspectives
Published in European journal of cancer care (01-05-2021)“…Objective Cancer patients are increasingly involved in decision‐making for cancer treatment. General practitioners' (GPs) support in this process is advocated…”
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Long-term Local Control and Overall Survival After Radiotherapy in Oligoprogressive Patients During Treatment With Checkpoint Inhibitors
Published in Anticancer research (01-10-2022)“…Background/Aim: Recent studies described the safety and clinical utility of combined anti-programmed cell death protein-1 (anti-PD1) checkpoint inhibition with…”
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Cerebrospinal fluid lymphocytosis: a hallmark of neurological complications during checkpoint inhibition
Published in European journal of cancer (1990) (01-11-2019)Get full text
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Association between Genetic Variants and Peripheral Neuropathy in Patients with NSCLC Treated with First-Line Platinum-Based Therapy
Published in Genes (07-01-2023)“…Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a common, disabling side effect in non-small cell lung cancer (NSCLC) patients treated with…”
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Prognostic factors for overall survival of stage III non-small cell lung cancer patients on computed tomography: A systematic review and meta-analysis
Published in Radiotherapy and oncology (01-10-2020)“…•This review includes data of 144,513 stage III NSCLC patients from 65 studies.•Most studies had medium methodological quality, failing to report one/more…”
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Ultra-central lung tumors: safety and efficacy of protracted stereotactic body radiotherapy
Published in Acta oncologica (03-08-2021)“…For patients with early stage or medically inoperable lung cancer, stereotactic body radiotherapy (SBRT) is a general accepted and effective treatment option…”
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Physical activity and checkpoint inhibition: association with toxicity and survival
Published in JNCI : Journal of the National Cancer Institute (05-04-2024)“…Although animal experiments suggest beneficial effects of physical activity (PA) on antitumor immunity, little is known about the effects of PA on immune…”
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Association of molecular status and metastatic organs at diagnosis in patients with stage IV non-squamous non-small cell lung cancer
Published in Lung cancer (Amsterdam, Netherlands) (01-07-2018)“…•NSCLC molecular status was associated with metastatic pattern at diagnosis.•EGFR+ tumors more often bone and pleural metastases than triple-negative.•EGFR+…”
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Patient-Reported Outcomes During Checkpoint Inhibition: Insight into Symptom Burden in Daily Clinical Practice
Published in Journal of pain and symptom management (01-06-2022)“…While praised for inducing durable anti-tumour responses, immune checkpoint inhibitors (ICI) also cause immune-related adverse events (irAEs) that can vary in…”
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Considerable interlaboratory variation in PD-L1 positivity in a nationwide cohort of non-small cell lung cancer patients
Published in Lung cancer (Amsterdam, Netherlands) (01-09-2021)“…•Considerable variation in PD-L1 positivity exists between pathology laboratories.•Variation is greatest when PD-L1 positivity is determined according to the…”
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Feasibility and first results of the 'Trials-within-Cohorts' (TwiCs) design in patients undergoing radiotherapy for lung cancer
Published in Acta oncologica (04-03-2023)“…'Trials-within-Cohorts' (TwiCs), previously known as 'cohort multiple randomized controlled trials' is a pragmatic trial design, supporting an efficient and…”
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Quantification of epicardial and peri-coronary fat using cardiac computed tomography; reproducibility and relation with obesity and metabolic syndrome in patients suspected of coronary artery disease
Published in Atherosclerosis (01-04-2008)“…Abstract Objective Adipose tissue surrounding coronary arteries may contribute to the development of coronary atherosclerosis given its localisation and…”
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