Search Results - "Linder, A. Elizabeth"

Serotonin (5-HT) in veins: not all in vain by Linder, A Elizabeth, Ni, Wei, Diaz, Jessica L, Szasz, Theodora, Burnett, Robert, Watts, Stephanie W

“…The circulatory system consists of veins and arteries. Compared with arteries, veins have been neglected in cardiovascular research. Although veins are…”
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Lack of the serotonin transporter (SERT) reduces the ability of 5-hydroxytryptamine to lower blood pressure by Patrick Davis, Robert, Linder, A. Elizabeth, Watts, Stephanie W.

“…Serotonin (5-hydroxytryptamine; 5-HT) is a potent constrictor of isolated blood vessels. However, recent studies demonstrate that chronic 5-HT infusion results…”
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Dynamic association of nitric oxide downstream signaling molecules with endothelial caveolin-1 in rat aorta by Linder, A Elizabeth, McCluskey, Lynnette P, Cole, 3rd, Kenneth R, Lanning, Katherine M, Webb, R Clinton

“…Classically, nitric oxide (NO) formed by endothelial NO synthase (eNOS) freely diffuses from its generation site to smooth muscle cells where it activates…”
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A serotonergic system in veins: serotonin transporter-independent uptake by Linder, A Elizabeth, Ni, Wei, Szasz, Theodora, Burnett, Robert, Diaz, Jessica, Geddes, Timothy J, Kuhn, Donald M, Watts, Stephanie W

“…We hypothesized that the 5-hydroxytryptamine (5-HT; serotonin) system is present and functional in veins. In vena cava (VC), the presence of the 5-HT synthesis…”
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Allopurinol Does Not Decrease Blood Pressure or Prevent the Development of Hypertension in the Deoxycorticosterone Acetate-Salt Rat Model by Szasz, Theodora, Linder, A Elizabeth, Davis, Robert P, Burnett, Robert, Fink, Gregory D, Watts, Stephanie W

“…Reactive oxygen species play an important role in the pathogenesis of hypertension, disease in which reactive oxygen species levels and markers of oxidative…”
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Uridine adenosine tetraphosphate induces contraction and relaxation in rat aorta by Linder, A. Elizabeth, Tumbri, Michelle, Linder, Felipe F.P, Webb, R. Clinton, Leite, Romulo

“…Abstract Uridine adenosine tetraphosphate (Up4 A) has been recently reported as an endothelium-derived vasoconstrictor and plasma levels of this dinucleotide…”
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Vascular reactivity, 5-HT uptake, and blood pressure in the serotonin transporter knockout rat by Linder, A Elizabeth, Diaz, Jessica, Ni, Wei, Szasz, Theo, Burnett, Robert, Watts, Stephanie W

“…The handling of serotonin [5-hydroxytryptamine (5-HT)] depends on the serotonin transporter (SERT). A SERT knockout (KO) rat is a useful model to test the…”
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Serotonin receptors in rat jugular vein: presence and involvement in the contraction by Linder, A Elizabeth, Gaskell, Geri L, Szasz, Theodora, Thompson, Janice M, Watts, Stephanie W

“…Serotonin (5-hydroxytryptamine; 5-HT) is released during platelet aggregation, a phenomenon commonly observed in blood clot formation and venous diseases. Once…”
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BODY DISTRIBUTION OF INFUSED SEROTONIN IN RATS by Linder, A Elizabeth, Beggs, Kevin M, Burnett, Robert J, Watts, Stephanie W

“…SUMMARY 1 Our goal was to investigate the body distribution of serotonin (5‐hydroxytryptamine; 5‐HT) in rats infused with 5‐HT (25 µg/kg per min) for 7 days…”
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Methyl-beta-cyclodextrin prevents angiotensin II-induced tachyphylactic contractile responses in rat aorta by Linder, A Elizabeth, Thakali, Keshari M, Thompson, Janice M, Watts, Stephanie W, Webb, R Clinton, Leite, Romulo

“…Tachyphylaxis or desensitization is frequently observed following angiotensin II type I (AT1) receptor activation by angiotensin II. One of the possible…”
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Erectile Function in Two‐Kidney, One‐Clip Hypertensive Rats is Maintained by a Potential Increase in Nitric Oxide Production by Linder, A. Elizabeth, Dorrance, Anne M., Mills, Thomas M., Webb, R. Clinton, Leite, Romulo

“…Hypertension is closely associated with erectile dysfunction (ED) as it has been observed in many experimental models of hypertension. Additionally,…”
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Penile erection requires association of soluble guanylyl cyclase with endothelial caveolin-1 in rat corpus cavernosum by Linder, A Elizabeth, Leite, Romulo, Lauria, Kimberly, Mills, Thomas M, Webb, R Clinton

“…Erectile dysfunction is caused by a variety of pathogenic factors, particularly impaired formation and action of nitric oxide (NO). NO released from nerve…”
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Altered Vascular Reactivity in Mice Made Hypertensive by Nitric Oxide Synthase Inhibition by Linder, A Elizabeth, Weber, David S, Whitesall, Steven E, DʼAlecy, Louis G, Webb, R Clinton

“…This study tested the hypothesis that nitric oxide (NO) synthase inhibition in mice would result in hypertension characterized by increased agonist-induced…”
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Inhibition of the tonic contraction in the treatment of erectile dysfunction by Jin, Liming, Linder, A Elizabeth, Mills, Thomas M, Webb, R Clinton

“…Erectile dysfunction (ED) reduces the quality of life. It is estimated that 52% of men have some degree of ED, which is associated with ageing. While it is…”
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The effect of drugs that alter serotonin homeostasis in rat erectile function by Linder, A. Elizabeth, Poli, Anicleto, de Lima e Silva, Ana Kelly

“…Abstract only We investigated wether antidepressants that alter serotonin (5‐hydroxytryptamine; 5‐HT) homeostasis impact rat erection due to 5‐HT uptake and…”
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Pharmacological characterization of the serotonin receptor mediating contraction in the rat jugular vein by Linder, A. Elizabeth, Gaskell, Geri, Watts, Stephanie W

“…Abstract only The purpose of this study was to characterize pharmacologically the serotonin (5‐hydroxytryptamine; 5‐HT) receptors mediating contraction in the…”
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Uric acid does not impact the endothelial‐dependent relaxation of aorta from normal and hypertensive rats by Szasz, Theodora, Linder, A Elizabeth, Watts, Stephanie W

“…Abstract only Vascular xanthine oxidase (XO) activity and superoxide, a product of this activity, increase in hypertension. Uric acid (UA), the other…”
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Function of the Serotonin Transporter in Vasculature of the Female Rat: comparison with the male by Linder, A. Elizabeth, Davis, Robert Patrick, Burnett, Robert, Watts, Stephanie W.

“…The serotonin transporter (SERT) handles serotonin (5-hydroxytryptamine, 5-HT) and is blocked by the antidepressant SERT inhibitors fluoxetine and fluvoxamine…”
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ALLOPURINOL DOES NOT DECREASE BLOOD PRESSURE OR PREVENT THE DEVELOPMENT OF HYPERTENSION IN THE DOCA-SALT RAT MODEL by Szasz, Theodora, Linder, A. Elizabeth, Davis, Robert P., Burnett, Robert, Fink, Gregory D., Watts, Stephanie W.

“…Reactive oxygen species (ROS) play an important role in the pathogenesis of hypertension, disease in which ROS levels and markers of oxidative stress are…”
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Serotonin Uptake in Veins, as Opposed to Arteries, Is Independent of the Serotonin Transporter by Linder, A. Elizabeth, Ni, Wei, Szasz, Theodora, Burnett, Robert, Watts, Stephanie W.

“…Abstract only Veins and arteries uptake serotonin (5‐hydroxytryptamine; 5‐HT). 5‐HT uptake in arteries depends on the 5‐HT transporter (5‐HTT), as it is…”
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