Search Results - "Lindenburg, Peter W."

Three-Phase Electroextraction: A New (Online) Sample Purification and Enrichment Method for Bioanalysis by Raterink, Robert-Jan, Lindenburg, Peter W, Vreeken, Rob J, Hankemeier, Thomas

“…The migration and at the same time enrichment of analytes from a liquid aqueous sample donor phase through an immiscible organic solvent layer acting as a…”
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PRMT3 inhibitor SGC707 reduces triglyceride levels and induces pruritus in Western-type diet-fed LDL receptor knockout mice by de Jong, Laura M., Zhang, Zhengzheng, den Hartog, Yvette, Sijsenaar, Timothy J. P., Martins Cardoso, Renata, Manson, Martijn L., Hankemeier, Thomas, Lindenburg, Peter W., Salvatori, Daniela C. F., Van Eck, Miranda, Hoekstra, Menno

“…Protein arginine methyltransferase 3 (PRMT3) is a co-activator of liver X receptor capable of selectively modulating hepatic triglyceride synthesis. Here we…”
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Scavenger Receptor BI Deficiency in Mice Is Associated With Plasma Ceramide and Sphingomyelin Accumulation and a Reduced Cholesteryl Ester Fatty Acid Length and Unsaturation Degree by Hoekstra, Menno, Zhang, Zhengzheng, Lindenburg, Peter W, Van Eck, Miranda

“…Scavenger receptor class B type I (SR-BI) is primarily known for its role in the selective uptake of cholesteryl esters (CEs) from high-density lipoproteins…”
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A Sample Preparation Method for the Simultaneous Profiling of Signaling Lipids and Polar Metabolites in Small Quantities of Muscle Tissues from a Mouse Model for Sarcopenia by He, Yupeng, van Mever, Marlien, Yang, Wei, Huang, Luojiao, Ramautar, Rawi, Rijksen, Yvonne, Vermeij, Wilbert P, Hoeijmakers, Jan H. J, Harms, Amy C, Lindenburg, Peter W, Hankemeier, Thomas

“…The metabolic profiling of a wide range of chemical classes relevant to understanding sarcopenia under conditions in which sample availability is limited,…”
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Flavor Profiling Using Comprehensive Mass Spectrometry Analysis of Metabolites in Tomato Soups by Leygeber, Simon, Grossmann, Justus L, Diez-Simon, Carmen, Karu, Naama, Dubbelman, Anne-Charlotte, Harms, Amy C, Westerhuis, Johan A, Jacobs, Doris M, Lindenburg, Peter W, Hendriks, Margriet M W B, Ammerlaan, Brenda C H, van den Berg, Marco A, van Doorn, Rudi, Mumm, Roland, Hall, Robert D, Smilde, Age K, Hankemeier, Thomas

“…Trained sensory panels are regularly used to rate food products but do not allow for data-driven approaches to steer food product development. This study…”
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An automated online three-phase electro-extraction setup with machine-vision process monitoring hyphenated to LC-MS analysis by He, Yupeng, Miggiels, Paul, Drouin, Nicolas, Lindenburg, Peter W., Wouters, Bert, Hankemeier, Thomas

“…Sample preparation is a labor-intensive and time-consuming procedure, especially for the bioanalysis of small-volume samples with low-abundant analytes. To…”
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Integration of three-phase microelectroextraction sample preparation into capillary electrophoresis by Oedit, Amar, Duivelshof, Bastiaan, Lindenburg, Peter W., Hankemeier, Thomas

“…•Three-phase electroextraction was coupled directly to capillary electrophoresis.•A new method for sensitive analysis of biogenic amines was…”
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Development of a fast, online three-phase electroextraction hyphenated to fast liquid chromatography–mass spectrometry for analysis of trace-level acid pharmaceuticals in plasma by He, Yupeng, Drouin, Nicolas, Wouters, Bert, Miggiels, Paul, Hankemeier, Thomas, Lindenburg, Peter W.

“…Sample preparation is a challenge for high-throughput analysis, especially for volume-limited samples with low-abundant analytes. Ideally, sample preparation…”
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Profiling acidic metabolites by capillary electrophoresis‐mass spectrometry in low numbers of mammalian cells using a novel chemical derivatization approach by Mever, Marlien, Willacey, Cornelius C. W., Zhang, Wei, Drouin, Nicolas, Christina, Alphert E., Lindenburg, Peter W., Veldhoven, Jaco P. D., Es, Daan, Harms, Amy C., Hankemeier, Thomas, Ramautar, Rawi

“…The simultaneous analysis of a broad range of polar ionogenic metabolites using capillary electrophoresis‐mass spectrometry (CE‐MS) can be challenging, as two…”
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On-line coupling of two-phase microelectroextraction to capillary electrophoresis – Mass spectrometry for metabolomics analyses by Oedit, Amar, Hankemeier, Thomas, Lindenburg, Peter W.

“…•Successful development of a fully automated two-phase electroextraction system.•Integration of two-phase electroextraction with CE and MS.•Electroextraction…”
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Recent developments in sample-pretreatment techniques for mass spectrometry-based metabolomics by Raterink, Robert-Jan, Lindenburg, Peter W., Vreeken, Rob J., Ramautar, Rawi, Hankemeier, Thomas

“…•Sample-pretreatment techniques for mass spectrometry-based metabolomics.•Emerging techniques not yet fully evaluated for metabolomics studies.•Automation and…”
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