Search Results - "Linden, Mika"

Mesoporous silica nanoparticles in medicine—Recent advances by Mamaeva, Veronika, Sahlgren, Cecilia, Lindén, Mika

“…MSNs have attracted increasing interest as drug carriers due to promising in vivo results in small-animal disease models, especially related to cancer therapy…”
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Superparamagnetic Core–Mesoporous Silica Shell Nanoparticles with Tunable Extra- and Intracellular Dissolution Rates by Fiedler, Richard, Sivakumaran, Gobika, Mallén, Jasmin, Lindén, Mika

“…Mesoporous silica nanoparticles have repeatedly been shown to be a promising drug carrier because of their high porosity, biocompatibility, and inherent…”
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Straightforward adsorption-based formulation of mesoporous silica nanoparticles for drug delivery applications by Schmid, Roman, Neffgen, Nathalie, Lindén, Mika

“…[Display omitted] Mesoporous silica nanoparticles (MSNs) have emerged as a very promising drug delivery platform. However, multi-step synthesis and surface…”
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Pore analysis of dendritic mesoporous silica nanoparticles by STEM tomography and nitrogen sorption by Beitzinger, Bastian, Walther, Paul, Lindén, Mika

“…Dendritic mesoporous silica nanoparticles (DMSN) provide a high diversity and complexity regarding their pore structure. Herein, we present results related to…”
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Towards multifunctional, targeted drug delivery systems using mesoporous silica nanoparticles--opportunities & challenges by Rosenholm, Jessica M, Sahlgren, Cecilia, Lindén, Mika

“…One of the big challenges of medicine today is to deliver drugs specifically to defected cells. Nanoparticulate drug carriers have the potential to answer to…”
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Confinement and Polarity Effects on the Peptide Packing Density on Mesoporous Silica Nanoparticles by Beitzinger, Bastian, Schmid, Roman, Jung, Christoph, Tiwary, Kanishka, Hermann, Patrick, Jacob, Timo, Lindén, Mika

“…The adsorption of cationic peptide JM21 onto different mesoporous silica nanoparticles (MSNs) from an aqueous solution was studied as a function of pH. In…”
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Investigation of the Mechanism of SiO2 Particle and Capsule Formation at the Oil–Water Interface of Dye-Stabilized Emulsions by Sihler, Susanne, Amenitsch, Heinz, Lindén, Mika, Ziener, Ulrich

“…In a previous contribution we described the formation of silica nanostructures in dye-stabilized nanoemulsions from tetraethyl orthosilicate droplets in water…”
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Serum Protein Adsorption Enhances Active Leukemia Stem Cell Targeting of Mesoporous Silica Nanoparticles by Beck, Michaela, Mandal, Tamoghna, Buske, Christian, Lindén, Mika

“…The functionalization of nanoparticles with a ligand targeting receptors overexpressed by the target cells is a commonly used strategy when aiming at…”
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On the importance of the linking chemistry for the PEGylation of mesoporous silica nanoparticles by von Baeckmann, Cornelia, Kählig, Hanspeter, Lindén, Mika, Kleitz, Freddy

“…[Display omitted] The typical method for minimizing serum protein adsorption in biological settings and prolonging blood circulation time of nanoparticles, is…”
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Nanoparticles in targeted cancer therapy: mesoporous silica nanoparticles entering preclinical development stage by Rosenholm, Jessica M, Mamaeva, Veronika, Sahlgren, Cecilia, Lindén, Mika

“…Nanotechnology may help overcome persisting limitations of current cancer treatment and thus contribute to the creation of more effective, safer and more…”
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Highly Transparent w/o Pickering Emulsions without Adjusting the Refractive Index of the Stabilizing Particles by Sihler, Susanne, Lindén, Mika, Ziener, Ulrich

“…Pickering emulsions with a remarkable transmittance of up to 86% across the visible spectrum have been prepared without adjusting the refractive index (RI) of…”
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Dissolution and morphology evolution of mesoporous silica nanoparticles under biologically relevant conditions by Lin, Chih-Yu, Yang, Chia-Min, Lindén, Mika

“…[Display omitted] Mesoporous silica nanoparticles (MSN) are promising drug vectors due to their high drug loading capacities, degradability under biologically…”
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Mesoporous silica nanoparticles in injectable hydrogels: factors influencing cellular uptake and viability by Baumann, Bernhard, Wittig, Rainer, Lindén, Mika

“…The incorporation of nanoparticles as drug vectors into 3D scaffolds has attracted a lot of recent interest. In particular, tissue engineering applications…”
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Towards establishing structure–activity relationships for mesoporous silica in drug delivery applications by Rosenholm, Jessica M., Lindén, Mika

“…Mesoporous silicas are currently widely studied carrier matrices in drug delivery applications. Surface functionalization of the silica is often employed in…”
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Targeting murine leukemic stem cells by antibody functionalized mesoporous silica nanoparticles by Mandal, Tamoghna, Beck, Michaela, Kirsten, Nicole, Lindén, Mika, Buske, Christian

“…Acute leukemia is initiated and maintained by leukemia stem cells (LSCs) and therefore there is great interest to develop innovative therapeutic approaches…”
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Targeted Intracellular Delivery of Hydrophobic Agents using Mesoporous Hybrid Silica Nanoparticles as Carrier Systems by Rosenholm, Jessica M, Peuhu, Emilia, Eriksson, John E, Sahlgren, Cecilia, Lindén, Mika

“…Targeted nanoparticle-mediated intracellular delivery is demonstrated using two hydrophobic fluorophores as model drug cargo. The presented hybrid carrier…”
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Wet-Chemical Analysis of Surface Concentration of Accessible Groups on Different Amino-Functionalized Mesoporous SBA-15 Silicas by Rosenholm, Jessica M, Lindén, Mika

“…Surface functionalization is one of the key steps toward the utilization of mesoporous materials in different applications. In this study, we characterized…”
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Impact of fluid flow rate on the dissolution behavior of bioactive glass S53P4 by Stiller, Adrian, Engblom, Markus, Karlström, Oskar, Lindén, Mika, Hupa, Leena

“…•Solution flow rate strongly influenced bioactive glass S53P4 dissolution behavior.•The release of ions to the solution was highly incongruent at the lowest…”
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Green Chemistry in Red Emulsion: Interface of Dye Stabilized Emulsions as a Powerful Platform for the Formation of sub-20-nm SiO2 Nanoparticles by Sihler, Susanne, Nguyen, Phuong Linh, Lindén, Mika, Ziener, Ulrich

“…Dye stabilized nanoemulsions offer the unique possibility of creating both silica capsules and sub-20-nm particles with precise control of particle size and…”
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Multifunctional mesoporous silica nanoparticles for combined therapeutic, diagnostic and targeted action in cancer treatment by Rosenholm, Jessica M, Sahlgren, Cecilia, Lindén, Mika

“…The main objective in the development of nanomedicine is to obtain delivery platforms for targeted delivery of drugs or imaging agents for improved therapeutic…”
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