Search Results - "Linden, Magdalena"

DNA methylation as a mediator of HLA-DRB1 15:01 and a protective variant in multiple sclerosis by Kular, Lara, Liu, Yun, Ruhrmann, Sabrina, Zheleznyakova, Galina, Marabita, Francesco, Gomez-Cabrero, David, James, Tojo, Ewing, Ewoud, Lindén, Magdalena, Górnikiewicz, Bartosz, Aeinehband, Shahin, Stridh, Pernilla, Link, Jenny, Andlauer, Till F.M, Gasperi, Christiane, Wiendl, Heinz, Zipp, Frauke, Gold, Ralf, Tackenberg, Björn, Weber, Frank, Hemmer, Bernhard, Strauch, Konstantin, Heilmann-Heimbach, Stefanie, Rawal, Rajesh, Schminke, Ulf, Schmidt, Carsten O, Kacprowski, Tim, Franke, Andre, Laudes, Matthias, Dilthey, Alexander T, Celius, Elisabeth Gulowsen, Søndergaard, Helle Bach, Tegnér, Jesper, Harbo, Hanne Flinstad, Oturai, Annette B, Olafsson, Sigurgeir, Eggertsson, Hannes P, Halldorsson, Bjarni V, Hjaltason, Haukur, Olafsson, Elias, Jonsdottir, Ingileif, Stefansson, Kari, Olsson, Tomas, Piehl, Fredrik, Ekström, Tomas J, Kockum, Ingrid, Feinberg, Andrew P, Jagodic, Maja

“…The human leukocyte antigen (HLA) haplotype DRB1*15:01 is the major risk factor for multiple sclerosis (MS). Here, we find that DRB1*15:01 is hypomethylated…”
Get full text

Impact of genetic risk loci for multiple sclerosis on expression of proximal genes in patients by James, Tojo, Lindén, Magdalena, Morikawa, Hiromasa, Fernandes, Sunjay Jude, Ruhrmann, Sabrina, Huss, Mikael, Brandi, Maya, Piehl, Fredrik, Jagodic, Maja, Tegnér, Jesper, Khademi, Mohsen, Olsson, Tomas, Gomez-Cabrero, David, Kockum, Ingrid

“…Abstract Despite advancements in genetic studies, it is difficult to understand and characterize the functional relevance of disease-associated genetic…”
Get full text

C-type lectin receptors Mcl and Mincle control development of multiple sclerosis-like neuroinflammation by N'diaye, Marie, Brauner, Susanna, Flytzani, Sevasti, Kular, Lara, Warnecke, Andreas, Adzemovic, Milena Z, Piket, Eliane, Min, Jin-Hong, Edwards, Will, Mela, Filia, Choi, Hoi Ying, Magg, Vera, James, Tojo, Linden, Magdalena, Reichardt, Holger M, Daws, Michael R, van Horssen, Jack, Kockum, Ingrid, Harris, Robert A, Olsson, Tomas, Guerreiro-Cacais, Andre O, Jagodic, Maja

“…Pattern recognition receptors (PRRs) are crucial for responses to infections and tissue damage; however, their role in autoimmunity is less clear. Herein we…”
Get full text

IL-22 Binding Protein Promotes the Disease Process in Multiple Sclerosis by Lindahl, Hannes, Guerreiro-Cacais, André O, Bedri, Sahl Khalid, Linnerbauer, Mathias, Lindén, Magdalena, Abdelmagid, Nada, Tandre, Karolina, Hollins, Claire, Irving, Lorraine, Glover, Colin, Jones, Clare, Alfredsson, Lars, Rönnblom, Lars, Kockum, Ingrid, Khademi, Mohsen, Jagodic, Maja, Olsson, Tomas

“…Genome-wide association studies have mapped the specific sequence variants that predispose for multiple sclerosis (MS). The pathogenic mechanisms that underlie…”
Get full text

Sex influences eQTL effects of SLE and Sjögren's syndrome-associated genetic polymorphisms by Lindén, Magdalena, Ramírez Sepúlveda, Jorge I, James, Tojo, Thorlacius, Gudny Ella, Brauner, Susanna, Gómez-Cabrero, David, Olsson, Tomas, Kockum, Ingrid, Wahren-Herlenius, Marie

“…Systemic lupus erythematosus (SLE) and primary Sjögren's syndrome (pSS) are autoimmune disorders characterized by autoantibodies, dysregulated B cells, and…”
Get full text

Lack of replication of interaction between EBNA1 IgG and smoking in risk for multiple sclerosis by Sundqvist, Emilie, Sundström, Peter, Lindén, Magdalena, Hedström, Anna Karin, Aloisi, Francesca, Hillert, Jan, Kockum, Ingrid, Alfredsson, Lars, Olsson, Tomas

“…BACKGROUND:Epstein-Barr virus infection, smoking, HLA-A*02, and DRB1*15 have all been proposed as risk factors for multiple sclerosis (MS). In 2010, Simon et…”
Get full text

C-type lectin receptors Mcl and Mincle contro development of multiple sclerosis like neuroinflammation by N'diaye, M, Brauner, S, Flytzani, S, Kular, L, Warnecke, A, Adzemovic, MZ, Piket, E, Min, J-H, Edwards, W, Mela, F

Get full text

Alterations in KLRB1 gene expression and a Scandinavian multiple sclerosis association study of the KLRB1 SNP rs4763655 by SØNDERGAARD, Helle Bach, SELLEBJERG, Finn, ROMME CHRISTENSEN, Jeppe, BÖRNSEN, Lars, SOELBERG SORENSEN, Per, BANG OTURAI, Annette, HILLERT, Jan, OLSSON, Tomas, KOCKUM, Ingrid, LINDEN, Magdalena, MERO, Inger-Lise, MYHR, Kjell-Morten, CELIUS, Elisabeth G, HARBO, Hanne F

“…Multiple sclerosis (MS) is a complex autoimmune disease affecting genetically susceptible individuals. A genome-wide association study performed by the…”
Get full text

Ethical Criteria for the Admission and Management of Patients in the ICU Under Conditions of Limited Medical Resources: A Shared International Proposal in View of the COVID-19 Pandemic by Tambone, Vittoradolfo, Boudreau, Donald, Ciccozzi, Massimo, Sanders, Karen, Campanozzi, Laura Leondina, Wathuta, Jane, Violante, Luciano, Cauda, Roberto, Petrini, Carlo, Abbate, Antonio, Alloni, Rossana, Argemi, Josepmaria, Argemí Renom, Josep, De Benedictis, Anna, Galerneau, France, García-Sánchez, Emilio, Ghilardi, Giampaolo, Hafler, Janet Palmer, Linden, Magdalena, Marcos, Alfredo, Onetti Muda, Andrea, Pandolfi, Marco, Pelaccia, Thierry, Picozzi, Mario, Revello, Ruben Oscar, Ricci, Giovanna, Rohrbaugh, Robert, Rossi, Patrizio, Sirignano, Ascanio, Spagnolo, Antonio Gioacchino, Stammers, Trevor, Velázquez, Lourdes, Agazzi, Evandro, Mercurio, Mark

Get full text

Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility by Patsopoulos, Nikolaos A., Baranzini, Sergio E., Santaniello, Adam, Shoostari, Parisa, Cotsapas, Chris, Wong, Garrett, Beecham, Ashley H., James, Tojo, Replogle, Joseph, Vlachos, Ioannis S., McCabe, Cristin, Pers, Tune H., Brandes, Aaron, White, Charles, Keenan, Brendan, Cimpean, Maria, Winn, Phoebe, Panteliadis, Ioannis-Pavlos, Robbins, Allison, Andlauer, Till F. M., Zarzycki, Onigiusz, Dubois, Bénédicte, Goris, An, Søndergaard, Helle Bach, Sellebjerg, Finn, Sorensen, Per Soelberg, Ullum, Henrik, Thørner, Lise Wegner, Saarela, Janna, Cournu-Rebeix, Isabelle, Damotte, Vincent, Fontaine, Bertrand, Guillot-Noel, Lena, Lathrop, Mark, Vukusic, Sandra, Berthele, Achim, Pongratz, Viola, Buck, Dorothea, Gasperi, Christiane, Graetz, Christiane, Grummel, Verena, Hemmer, Bernhard, Hoshi, Muni, Knier, Benjamin, Korn, Thomas, Lill, Christina M., Luessi, Felix, Mühlau, Mark, Zipp, Frauke, Dardiotis, Efthimios, Agliardi, Cristina, Amoroso, Antonio, Barizzone, Nadia, Benedetti, Maria D., Bernardinelli, Luisa, Cavalla, Paola, Clarelli, Ferdinando, Comi, Giancarlo, Cusi, Daniele, Esposito, Federica, Ferrè, Laura, Galimberti, Daniela, Guaschino, Clara, Leone, Maurizio A., Martinelli, Vittorio, Moiola, Lucia, Salvetti, Marco, Sorosina, Melissa, Vecchio, Domizia, Zauli, Andrea, Santoro, Silvia, Mancini, Nicasio, Zuccalà, Miriam, Mescheriakova, Julia, van Duijn, Cornelia, Bos, Steffan D., Celius, Elisabeth G., Spurkland, Anne, Comabella, Manuel, Montalban, Xavier, Alfredsson, Lars, Bomfim, Izaura L., Gomez-Cabrero, David, Hillert, Jan, Jagodic, Maja, Lindén, Magdalena, Piehl, Fredrik, Jelčić, Ilijas, Martin, Roland, Sospedra, Mirela, Baker, Amie, Ban, Maria, Hawkins, Clive, Hysi, Pirro, Kalra, Seema, Karpe, Fredrik, Khadake, Jyoti, Lachance, Genevieve, Molyneux, Paul, Neville, Matthew

“…We analyzed genetic data of 47,429 multiple sclerosis (MS) and 68,374 control subjects and established a reference map of the genetic architecture of MS that…”
Get full text

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis by Beecham, Ashley H, Patsopoulos, Nikolaos A, Xifara, Dionysia K, Davis, Mary F, Kemppinen, Anu, Cotsapas, Chris, Shah, Tejas S, Spencer, Chris, Booth, David, Goris, An, Oturai, Annette, Saarela, Janna, Fontaine, Bertrand, Hemmer, Bernhard, Martin, Claes, Zipp, Frauke, D'Alfonso, Sandra, Martinelli-Boneschi, Filippo, Taylor, Bruce, Harbo, Hanne F, Kockum, Ingrid, Hillert, Jan, Olsson, Tomas, Ban, Maria, Oksenberg, Jorge R, Hintzen, Rogier, Barcellos, Lisa F, Agliardi, Cristina, Alfredsson, Lars, Alizadeh, Mehdi, Anderson, Carl, Andrews, Robert, Søndergaard, Helle Bach, Baker, Amie, Band, Gavin, Baranzini, Sergio E, Barizzone, Nadia, Barrett, Jeffrey, Bellenguez, Céline, Bergamaschi, Laura, Bernardinelli, Luisa, Berthele, Achim, Biberacher, Viola, Binder, Thomas M C, Blackburn, Hannah, Bomfim, Izaura L, Brambilla, Paola, Broadley, Simon, Brochet, Bruno, Brundin, Lou, Buck, Dorothea, Butzkueven, Helmut, Caillier, Stacy J, Camu, William, Carpentier, Wassila, Cavalla, Paola, Celius, Elisabeth G, Coman, Irène, Comi, Giancarlo, Corrado, Lucia, Cosemans, Leentje, Cournu-Rebeix, Isabelle, Cree, Bruce A C, Cusi, Daniele, Damotte, Vincent, Defer, Gilles, Delgado, Silvia R, Deloukas, Panos, di Sapio, Alessia, Dilthey, Alexander T, Donnelly, Peter, Dubois, Bénédicte, Duddy, Martin, Edkins, Sarah, Elovaara, Irina, Esposito, Federica, Evangelou, Nikos, Fiddes, Barnaby, Field, Judith, Franke, Andre, Freeman, Colin, Frohlich, Irene Y, Galimberti, Daniela, Gieger, Christian, Gourraud, Pierre-Antoine, Graetz, Christiane, Graham, Andrew, Grummel, Verena, Guaschino, Clara, Hadjixenofontos, Athena, Hakonarson, Hakon, Halfpenny, Christopher, Hall, Gillian, Hall, Per, Hamsten, Anders, Harley, James, Harrower, Timothy, Hawkins, Clive, Hellenthal, Garrett, Hillier, Charles

“…The International Multiple Sclerosis Genetics Consortium reports the discovery of 48 new susceptibility variants for multiple sclerosis through targeted…”
Get full text

DNA methylation as a mediator of HLA-DRB115:01 and a protective variant in multiple sclerosis by Kular, Lara, Liu, Yun, Ruhrmann, Sabrina, Zheleznyakova, Galina, Marabita, Francesco, Gomez-Cabrero, David, James, Tojo, Ewing, Ewoud, Lindén, Magdalena, Górnikiewicz, Bartosz, Aeinehband, Shahin, Stridh, Pernilla, Link, Jenny, Andlauer, Till F. M., Gasperi, Christiane, Wiendl, Heinz, Zipp, Frauke, Gold, Ralf, Tackenberg, Björn, Weber, Frank, Hemmer, Bernhard, Strauch, Konstantin, Heilmann-Heimbach, Stefanie, Rawal, Rajesh, Schminke, Ulf, Schmidt, Carsten O., Kacprowski, Tim, Franke, Andre, Laudes, Matthias, Dilthey, Alexander T., Celius, Elisabeth G., Søndergaard, Helle B., Tegnér, Jesper, Harbo, Hanne F., Oturai, Annette B., Olafsson, Sigurgeir, Eggertsson, Hannes P., Halldorsson, Bjarni V., Hjaltason, Haukur, Olafsson, Elias, Jonsdottir, Ingileif, Stefansson, Kari, Olsson, Tomas, Piehl, Fredrik, Ekström, Tomas J., Kockum, Ingrid, Feinberg, Andrew P., Jagodic, Maja

“…The human leukocyte antigen (HLA) haplotype DRB1*15 : 01 is the major risk factor for multiple sclerosis (MS). Here, we find that DRB1*15 : 01 is…”
Get full text

Studies of Risk Loci in Multiple Sclerosis by Lindén, Magdalena

“…Multiple sclerosis (MS), a chronic inflammatory disease of the central nervous system, is one of the most common causes of neurological disability among young…”
Get full text

Alterations in gene expression and a Scandinavian multiple sclerosis association study of the SNP rs4763655 by Søndergaard, Helle Bach, Sellebjerg, Finn, Hillert, Jan, Olsson, Tomas, Kockum, Ingrid, Lindén, Magdalena, Mero, Inger-Lise, Myhr, Kjell-Morten, Celius, Elisabeth Gulowsen, Harbo, Hanne Flinstad, Christensen, Jeppe Romme, Börnsen, Lars, Soelberg Sorensen, Per, Oturai, Annette Bang

“…Multiple sclerosis (MS) is a complex autoimmune disease affecting genetically susceptible individuals. A genome-wide association study performed by the…”
Get full text