Search Results - "Lindel, Thomas"

Chemistry and Biology of the Pyrrole-Imidazole Alkaloids by Lindel, Thomas

“…More than a decade after our last review on the chemistry of the pyrrole-imidazole alkaloids, it was time to analyze once more the developments in that field…”
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Synthesis of (−)‐Dihydroraputindole D by Enantioselective Benzoylation of a 1,3‐Diol Intermediate by Fresia, Marvin, Kock, Mario, Lindel, Thomas

“…The enantioselective synthesis of (−)‐dihydroraputindole D is reported. The key step is the desymmetrizing benzoylation of a prochiral 1,3‐diol employing…”
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Incorporation of 4J-HMBC and NOE Data into Computer-Assisted Structure Elucidation with WebCocon by Köck, Matthias, Lindel, Thomas, Junker, Jochen

“…Over the past decades, different software programs have been developed for the Computer-Assisted Structure Elucidation (CASE) with NMR data using with various…”
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Microwave-Assisted Fluorination of 2-Acylpyrroles: Synthesis of Fluorohymenidin by Troegel, Benjamin, Lindel, Thomas

“…Treatment of mono- and nonbrominated 2-acylpyrroles with Selectfluor under microwave conditions leads to fluorination of the pyrrole ring in the 5-position. In…”
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Synthesis of the polyketide section of seragamide A and related cyclodepsipeptides via Negishi cross coupling by Lang, Jan Hendrik, Lindel, Thomas

“…The synthesis of the polyketide section present in the potently cytotoxic marine cyclodepsipeptide jasplakinolide and related natural products, geodiamolides…”
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Synthesis and Photooxidation of the Trisubstituted Oxazole Fragment of the Marine Natural Product Salarin C by Schäckermann, Jan-Niklas, Lindel, Thomas

“…The eastern section of the macrocyclic marine natural product salarin C from the sponge Fascaplysinopsis sp. was synthesized employing a halogen dance reaction…”
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Total Synthesis and Absolute Configuration of Raputindole A by Kock, Mario, Jones, Peter G, Lindel, Thomas

“…The first total synthesis of the bisindole alkaloid raputindole A from the rutaceous plant Raputia simulans is reported. The key step is a Au­(I)-catalyzed…”
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L-Phototryptophan by Wartmann, Thomas, Lindel, Thomas

“…Phototryptophan is a new photoactivatable amino acid designed to be incorporated into tryptophan‐containing peptides for photoaffinity labeling. The synthesis…”
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Photoactivation of (p-Methoxyphenyl)(trifluoromethyl)diazirine in the Presence of Phenolic Reaction Partners by Raimer, Björn, Lindel, Thomas

“…Shine light on your chemistry! Irradiating 3‐(4‐methoxyphenyl)‐3‐(trifluoromethyl)‐3H‐diazirine in the presence of equimolar solutions of phenol and tyrosine…”
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Fluorescent analogs of the marine natural product psammaplin A: synthesis and biological activity by Hentschel, Fabia, Sasse, Florenz, Lindel, Thomas

“…The symmetrical disulfide psammaplin A from the marine sponge Pseudoceratina sp. was synthesized and structurally altered by replacement of one of the…”
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Study on the synthesis of the cyclopenta[f]indole core of raputindole A by Marsch, Nils, Kock, Mario, Lindel, Thomas

“…The raputindoles from the rutaceous tree Raputia simulans share a cyclopenta[f]indole partial structure the synthesis of which is subject of this…”
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Synthesis of eunicellane-type bicycles embedding a 1,3-cyclohexadiene moiety by Frichert, Alex, Jones, Peter G, Lindel, Thomas

“…The first synthesis of diterpenoid eunicellane skeletons incorporating a 1,3-cyclohexadiene moiety is presented. Key step is a low-valent titanium-induced…”
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SmI2-mediated dimerization of indolylbutenones and synthesis of the myxobacterial natural product indiacen B by Marsch, Nils, Jones, Peter G, Lindel, Thomas

“…The synthesis and reactivity of indole derivatives substituted in the benzene section was studied. Starting materials 4- and 6-iodoindole were conveniently…”
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Total Synthesis of Flustramine C via Dimethylallyl Rearrangement by Lindel, Thomas, Bräuchle, Laura, Golz, Gregor, Böhrer, Petra

“…The marine natural product flustramine C from the bryozoan Flustra foliacea was synthesized in five steps and 38% yield starting from N b-methyltryptamine. The…”
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Pinacol Approach to the Eunicellane Skeleton by Al Batal, Mona, Jones, Peter G., Lindel, Thomas

“…A short route to a partially aromatic version of the eunicellane skeleton, which occurs in cytostatic marine diterpenoids, was developed. The key step is the…”
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Identification of superoxide production by Arabidopsis thaliana aldehyde oxidases AAO1 and AAO3 by Zarepour, Maryam, Simon, Kristina, Wilch, Moritz, Nieländer, Ute, Koshiba, Tomokazu, Seo, Mitsunori, Lindel, Thomas, Bittner, Florian

“…Plant aldehyde oxidases (AOs) have gained great attention during the last years as they catalyze the last step in the biosynthesis of the phytohormone abscisic…”
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Total Synthesis of the Cytostatic Marine Natural Product Dibromophakellstatin via Three-Component Imidazolidinone Anellation by Zöllinger, Michael, Mayer, Peter, Lindel, Thomas

“…The tetracyclic pyrrole−imidazole alkaloid dibromophakellstatin from the marine sponge Phakellia mauritiana has been synthesized within seven steps from…”
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Total Synthesis of the Marine Natural Product rac-Dibromophakellstatin by Jacquot, Delphine E. N., Zöllinger, Michael, Lindel, Thomas

“…The pyrrole‐imidazole alkaloid dibromophakellstatin (1) from the marine sponge Phakellia mauritiana was synthesized in only five steps starting from…”
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Antitumor activity of the marine natural product dibromophakellstatin in vitro by Zöllinger, Michael, Kelter, Gerhard, Fiebig, Heinz-Herbert, Lindel, Thomas

“…The pyrrole-imidazole alkaloid rac-dibromophakellstatin displayed selective antitumor activity in vitro when tested in 36 cell lines in a cell survival and…”
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Synthesis of Pyranocyclopentaindolines Representing the Western Sections of Janthitrem B, JBIR‐137, and Shearinine G by Fresia, Marvin, Lindel, Thomas

“…The synthesis of the ABCD tetracyclic partial structures of the fungal indole diterpenes janthitrem B, JBIR‐137, and shearinine G is reported. The route starts…”
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