Search Results - "Linde, Robert G."

A formal synthesis of FK-506. Exploration of some alternatives to macrolactamization by Jones, A. Brian, Villalobos, Annabella, Linde, Robert G, Danishefsky, Samuel J

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Enantioselective preparation of functionalized cyclopentanoids via a common chiral (.pi.-allyl)palladium complex by Deardorff, Donald R, Linde, Robert G, Martin, Amanda M, Shulman, Michael J

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The identification of orally bioavailable thrombopoietin agonists by Munchhof, Michael J., Antipas, Amy S., Blumberg, Laura C., Brissette, William H., Brown, Matthew F., Casavant, Jeffrey M., Doty, Jonathan L., Driscoll, James, Harris, Thomas M., Wolf-Gouveia, Lilli A., Jones, Christopher S., Li, Qifang, Linde, Robert G., Lira, Paul D., Marfat, Anthony, McElroy, Eric, Mitton-Fry, Mark, McCurdy, Sandra P., Reiter, Lawrence A., Ripp, Sharon L., Shavnya, Andrei, Thomasco, Lisa M., Trevena, Kristen A.

“…Progress towards the identification of bioavailable drug-like thrombopoietin agonist is reported. Recently, we disclosed a series of potent pyrimidine…”
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Pyrimidine benzamide-based thrombopoietin receptor agonists by Reiter, Lawrence A., Subramanyam, Chakrapani, Mangual, Emilio J., Jones, Christopher S., Smeets, Marc I., Brissette, William H., McCurdy, Sandra P., Lira, Paul D., Linde, Robert G., Li, Qifang, Zhang, Fangning, Antipas, Amy S., Blumberg, Laura C., Doty, Jonathan L., Driscoll, James P., Munchhof, Michael J., Ripp, Sharon L., Shavnya, Andrei, Shepard, Richard M., Sperger, Diana, Thomasco, Lisa M., Trevena, Kristen A., Wolf-Gouveia, Lilli A., Zhang, Liling

“…A series of pyrimidine benzamide-based thrombopoietin receptor agonists is described. The lead molecule contains a 2-amino-5-unsubstituted thiazole, a group…”
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Straightforward synthesis of 1,2,3-tricarbonyl systems by Linde, Robert G, Jeroncic, Lucio O, Danishefsky, Samuel J

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Efficient preparation of intermediates corresponding to C22-C27 and C28-C34 of FK-506 by Linde, Robert G, Egbertson, Melissa, Coleman, Robert S, Jones, A. Brian, Danishefsky, Samuel J

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Palladium-catalyzed syn 1,4-additions of silyl-derived carboxylates and phenoxides to cyclopentadiene monoepoxide. A stereo- and regiocontrolled route to differentially protected cis-2-cyclopentene-1,4-diols by Deardorff, Donald R, Shambayati, Soroosh, Linde, Robert G, Dunn, Monty M

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