Search Results - "Lindberg, Eric L"

Ablation of lysophosphatidic acid receptor 1 attenuates hypertrophic cardiomyopathy in a mouse model by Axelsson Raja, Anna, Wakimoto, Hiroko, DeLaughter, Daniel M, Reichart, Daniel, Gorham, Joshua, Conner, David A, Lun, Mingyue, Probst, Clemens K, Sakai, Norihiko, Knipe, Rachel S, Montesi, Sydney B, Shea, Barry, Adam, Leonard P, Leinwand, Leslie A, Wan, William, Choi, Esther Sue, Lindberg, Eric L, Patone, Giannino, Noseda, Michela, Hübner, Norbert, Seidman, Christine E, Tager, Andrew M, Seidman, J G, Ho, Carolyn Y

“…Myocardial fibrosis is a key pathologic feature of hypertrophic cardiomyopathy (HCM). However, the fibrotic pathways activated by HCM-causing sarcomere protein…”
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Isolation of Nuclei from Mammalian Cells and Tissues for Single-Nucleus Molecular Profiling by Nadelmann, Emily R, Gorham, Joshua M, Reichart, Daniel, Delaughter, Daniel M, Wakimoto, Hiroko, Lindberg, Eric L, Litviňukova, Monika, Maatz, Henrike, Curran, Justin J, Ischiu Gutierrez, Daniela, Hübner, Norbert, Seidman, Christine E, Seidman, J G

“…Both single-cell RNA sequencing (scRNAseq) and single-nucleus RNA sequencing (snRNAseq) can be used to characterize the transcriptional profile of individual…”
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Cells of the adult human heart by Litviňuková, Monika, Talavera-López, Carlos, Maatz, Henrike, Reichart, Daniel, Worth, Catherine L., Lindberg, Eric L., Kanda, Masatoshi, Polanski, Krzysztof, Heinig, Matthias, Lee, Michael, Nadelmann, Emily R., Roberts, Kenny, Tuck, Liz, Fasouli, Eirini S., DeLaughter, Daniel M., McDonough, Barbara, Wakimoto, Hiroko, Gorham, Joshua M., Samari, Sara, Mahbubani, Krishnaa T., Saeb-Parsy, Kourosh, Patone, Giannino, Boyle, Joseph J., Zhang, Hongbo, Zhang, Hao, Viveiros, Anissa, Oudit, Gavin Y., Bayraktar, Omer Ali, Seidman, J. G., Seidman, Christine E., Noseda, Michela, Hubner, Norbert, Teichmann, Sarah A.

“…Cardiovascular disease is the leading cause of death worldwide. Advanced insights into disease mechanisms and therapeutic strategies require a deeper…”
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The Translational Landscape of the Human Heart by van Heesch, Sebastiaan, Witte, Franziska, Schneider-Lunitz, Valentin, Schulz, Jana F., Adami, Eleonora, Faber, Allison B., Kirchner, Marieluise, Maatz, Henrike, Blachut, Susanne, Sandmann, Clara-Louisa, Kanda, Masatoshi, Worth, Catherine L., Schafer, Sebastian, Calviello, Lorenzo, Merriott, Rhys, Patone, Giannino, Hummel, Oliver, Wyler, Emanuel, Obermayer, Benedikt, Mücke, Michael B., Lindberg, Eric L., Trnka, Franziska, Memczak, Sebastian, Schilling, Marcel, Felkin, Leanne E., Barton, Paul J.R., Quaife, Nicholas M., Vanezis, Konstantinos, Diecke, Sebastian, Mukai, Masaya, Mah, Nancy, Oh, Su-Jun, Kurtz, Andreas, Schramm, Christoph, Schwinge, Dorothee, Sebode, Marcial, Harakalova, Magdalena, Asselbergs, Folkert W., Vink, Aryan, de Weger, Roel A., Viswanathan, Sivakumar, Widjaja, Anissa A., Gärtner-Rommel, Anna, Milting, Hendrik, dos Remedios, Cris, Knosalla, Christoph, Mertins, Philipp, Landthaler, Markus, Vingron, Martin, Linke, Wolfgang A., Seidman, Jonathan G., Seidman, Christine E., Rajewsky, Nikolaus, Ohler, Uwe, Cook, Stuart A., Hubner, Norbert

“…Gene expression in human tissue has primarily been studied on the transcriptional level, largely neglecting translational regulation. Here, we analyze the…”
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Intramyocardial Sprouting Tip Cells Specify Coronary Arterialization by Cano, Elena, Schwarzkopf, Jennifer, Kanda, Masatoshi, Lindberg, Eric L, Hollfinger, Irene, Pogontke, Cristina, Braeuning, Caroline, Fischer, Cornelius, Hübner, Norbert, Gerhardt, Holger

“…The elaborate patterning of coronary arteries critically supports the high metabolic activity of the beating heart. How coronary endothelial cells coordinate…”
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Pathogenic variants damage cell composition and single cell transcription in cardiomyopathies by Reichart, Daniel, Lindberg, Eric L, Maatz, Henrike, Miranda, Antonio M A, Viveiros, Anissa, Shvetsov, Nikolay, Gärtner, Anna, Nadelmann, Emily R, Lee, Michael, Kanemaru, Kazumasa, Ruiz-Orera, Jorge, Strohmenger, Viktoria, DeLaughter, Daniel M, Patone, Giannino, Zhang, Hao, Woehler, Andrew, Lippert, Christoph, Kim, Yuri, Adami, Eleonora, Gorham, Joshua M, Barnett, Sam N, Brown, Kemar, Buchan, Rachel J, Chowdhury, Rasheda A, Constantinou, Chrystalla, Cranley, James, Felkin, Leanne E, Fox, Henrik, Ghauri, Ahla, Gummert, Jan, Kanda, Masatoshi, Li, Ruoyan, Mach, Lukas, McDonough, Barbara, Samari, Sara, Shahriaran, Farnoush, Yapp, Clarence, Stanasiuk, Caroline, Theotokis, Pantazis I, Theis, Fabian J, van den Bogaerdt, Antoon, Wakimoto, Hiroko, Ware, James S, Worth, Catherine L, Barton, Paul J R, Lee, Young-Ae, Teichmann, Sarah A, Milting, Hendrik, Noseda, Michela, Oudit, Gavin Y, Heinig, Matthias, Seidman, Jonathan G, Hubner, Norbert, Seidman, Christine E

“…Pathogenic variants in genes that cause dilated cardiomyopathy (DCM) and arrhythmogenic cardiomyopathy (ACM) convey high risks for the development of heart…”
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Extracellular Matrix in Heart Failure: Role of ADAMTS5 in Proteoglycan Remodeling by Barallobre-Barreiro, Javier, Radovits, Tamás, Fava, Marika, Mayr, Ursula, Lin, Wen-Yu, Ermolaeva, Elizaveta, Martínez-López, Diego, Lindberg, Eric L., Duregotti, Elisa, Daróczi, László, Hasman, Maria, Schmidt, Lukas E., Singh, Bhawana, Lu, Ruifang, Baig, Ferheen, Siedlar, Aleksandra Malgorzata, Cuello, Friederike, Catibog, Norman, Theofilatos, Konstantinos, Shah, Ajay M., Crespo-Leiro, Maria G., Doménech, Nieves, Hübner, Norbert, Merkely, Béla, Mayr, Manuel

“…Remodeling of the extracellular matrix (ECM) is a hallmark of heart failure (HF). Our previous analysis of the secretome of murine cardiac fibroblasts returned…”
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Interleukin 11 therapy causes acute left ventricular dysfunction by Sweeney, Mark, O'Fee, Katie, Villanueva-Hayes, Chelsie, Rahman, Ekhlas, Lee, Michael, Tam, Chung Nga, Pascual-Navarro, Eneko, Maatz, Henrike, Lindberg, Eric L, Vanezis, Konstantinos, Ramachandra, Chrishan J, Andrew, Ivan, Jennings, Emma R, Lim, Wei-Wen, Widjaja, Anissa A, Carling, David, Hausenloy, Derek J, Hubner, Norbert, Barton, Paul J R, Cook, Stuart A

“…Interleukin 11 (IL11) was initially thought important for platelet production, which led to recombinant IL11 being developed as a drug to treat…”
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Amplification of autoimmune organ damage by NKp46-activated ILC1s by Biniaris-Georgallis, Stylianos-Iason, Aschman, Tom, Stergioula, Katerina, Schreiber, Frauke, Jafari, Vajiheh, Taranko, Anna, Karmalkar, Tejal, Kasapi, Ana, Lenac Rovis, Tihana, Jelencic, Vedrana, Bejarano, David A., Fabry, Lea, Papacharalampous, Michail, Mattiola, Irene, Molgora, Martina, Hou, Jinchao, Hublitz, Karolin W., Heinrich, Frederik, Guerra, Gabriela Maria, Durek, Pawel, Patone, Giannino, Lindberg, Eric L., Maatz, Henrike, Hölsken, Oliver, Krönke, Gerhard, Mortha, Arthur, Voll, Reinhard E., Clarke, Alexander J., Hauser, Anja E., Colonna, Marco, Thurley, Kevin, Schlitzer, Andreas, Schneider, Christoph, Stamatiades, Efstathios G., Mashreghi, Mir-Farzin, Jonjic, Stipan, Hübner, Norbert, Diefenbach, Andreas, Kanda, Masatoshi, Triantafyllopoulou, Antigoni

“…In systemic lupus erythematosus, loss of immune tolerance, autoantibody production and immune complex deposition are required but not sufficient for organ…”
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AntiSplodge: a neural-network-based RNA-profile deconvolution pipeline designed for spatial transcriptomics by Lund, Jesper B, Lindberg, Eric L, Maatz, Henrike, Pottbaecker, Fabian, Hübner, Norbert, Lippert, Christoph

“…Abstract With the current surge of spatial transcriptomics (ST) studies, researchers are exploring the deep interactive cell-play directly in tissues, in situ…”
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The Extracellular Matrix in Heart Failure: The Role of Adamts5 In Proteoglycan Remodelling by Barallobre-Barreiro, Javier, Radovits, Tamás, Fava, Marika, Mayr, Ursula, Lin, Wen-Yu, Ermolaeva, Elizaveta, Martínez-López, Diego, Lindberg, Eric L., Duregotti, Elisa, Daróczi, László, Hasman, Maria, Schmidt, Lukas E., Singh, Bhawana, Lu, Ruifang, Baig, Ferheen, Siedlar, Aleksandra Malgorzata, Cuello, Friederike, Catibog, Norman, Theofilatos, Konstantinos, Shah, Ajay M., Crespo-Leiro, Maria G., Doménech, Nieves, Hübner, Norbert, Merkely, Béla, Mayr, Manuel

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Liver transcriptome analysis reveals PSC-attributed gene set associated with fibrosis progression by Laschtowitz, Alena, Lindberg, Eric L., Liebhoff, Anna-Maria, Liebig, Laura Anne, Casar, Christian, Steinmann, Silja, Guillot, Adrien, Xu, Jun, Schwinge, Dorothee, Trauner, Michael, Lohse, Ansgar Wilhelm, Bonn, Stefan, Hübner, Norbert, Schramm, Christoph

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