Search Results - "Lindamood, Charles"

Effects of Milnacipran on Cardiac Repolarization in Healthy Participants by Periclou, Antonia, Palmer, Robert H., Zheng, Hongjie, Lindamood III, Charles

“…Milnacipran is approved for management of fibromyalgia in the United States. In this double‐blind, placebo‐ and active drug‐controlled study (N = 100), effects…”
Get full text

Biologically Active Heteroarotinoids Exhibiting Anticancer Activity and Decreased Toxicity by Benbrook, Doris M, Madler, Matora M, Spruce, Lyle W, Birckbichler, Paul J, Nelson, Eldon C, Subramanian, Shankar, Weerasekare, G. Mahika, Gale, Jonathan B, Patterson, Manford K, Wang, Binghe, Wang, Wei, Lu, Shennan, Rowland, Tami C, DiSivestro, Paul, Lindamood, Charles, Hill, Donald L, Berlin, K. Darrell

“…A series of retinoids, containing heteroatoms in a cyclic ring and called heteroarotinoids, were synthesized, and their biological activity was evaluated using…”
Get full text

Effects of Commonly Administered Agents and Genetics on Nebivolol Pharmacokinetics: Drug-Drug Interaction Studies by Lindamood, Charles, Ortiz, Stephan, Shaw, Andrew, Rackley, Russ, Gorski, J. Christopher

“…Drug interactions are a significant clinical concern, particularly in patients with conditions such as heart disease and hypertension, in whom coadministration…”
Get full text

Effects of retinoids on metabolizing enzymes and on binding of benzo(a)pyrene to rat tissue DNA by MCCARTHY, D. J, LINDAMOOD III, C, HILL, D. L

“…Retinyl acetate, 13-cis-retinoic acid (13cisRA), and N-(4-hydroxyphenyl)-retinamide (4HPR) were assayed for their in vivo effects on hepatic levels of…”
Get full text

Effects of marihuana cannabinoids on seizure activity in cobalt-epileptic rats by Colasanti, B K, Lindamood, 3rd, C, Craig, C R

“…Rats rendered chronically epileptic by bilateral implantation of cobalt into frontal cortices were simultaneously prepared with permanent electrodes for…”
Get more information

Subchronic Toxicity of Human Immunodeficiency Virus and Tuberculosis Combination Therapies in B6C3F1 Mice by Rao, Ghanta N., Lindamood, Charles, Heath, James E., Farnell, Daniel R., Giles, Herschell D.

“…Combination therapy with anti-HIV drugs and opportunistic infection drugs is a common practice in treatment of AIDS patients. Although toxic effects of most…”
Get full text

Toxicity and carcinogenicity of t-butyl alcohol in rats and mice following chronic exposure in drinking water by Cirvello, J D, Radovsky, A, Heath, J E, Farnell, D R, Lindamood, 3rd, C

“…t-Butyl alcohol (TBA) was administered in drinking water to F344/N rats and B6C3F1 mice for two years using 60 animals/dose/sex/species. Male rats received…”
Get more information

Retrospective Study of Possible α-2μ-Globulin Nephropathy and Associated Cell Proliferation in Male Fischer 344 Rats Dosed with t-Butyl Alcohol by Takahashi, Kimimasa, Lindamood, Charles, Maronpot, Robert R.

“…Tert-butyl alcohol, an important commodity chemical, additive to unleaded gasoline, and contaminant of drinking water, was evaluated for toxicity and was found…”
Get full text

Retrospective Study of Possible a-2m-Globulin Nephropathy and Associated Cell Proliferation in Male Fischer 344 Rats Dosed with t-Butyl Alcohol by Takahashi, Kimimasa, Lindamood, Charles, Maronpot, Robert R.

Get full text

Subchronic Toxicity of Human Immunodeficiency Virus and Tuberculosis Combination Therapies in B6C3F1 Mice by Rao, Ghanta N., Lindamood, Charles, Heath, James E., Farnell, Daniel R., Giles, Herschell D.

“…Combination therapy with anti-HIV drugs and opportunistic infection drugs is a common practice in treatment of AIDS patients. Although toxic effects of most…”
Get full text

Retinoid-induced hemorrhaging and bone toxicity in rats fed diets deficient in vitamin K by McCarthy, D J, Lindamood, 3rd, C, Gundberg, C M, Hill, D L

“…The recent increase in the clinical use of synthetic vitamin A compounds has led to concern of possible side effects. Some of these effects are known to be…”
Get more information

Acoustic-phonetic skills and reading: Kindergarten through twelfth grade by Calfee, Robert C, Lindamood, Patricia, Lindamood, Charles

“…Tested 660 kindergarten through Grade 12 Ss on their ability to match discrete and integrated phonetic segments using a sequence of colored blocks to represent…”
Get full text

Toxicologic and immunologic evaluations of N-(all-trans-retinoyl)-DL-leucine and N-(all-trans-retinoyl)glycine by Lindamood, 3rd, C, Dillehay, D L, Lamon, E W, Giles, H D, Shealy, Y F, Sani, B P, Hill, D L

“…Sprague-Dawley rats were dosed by gavage daily for 28 days with 5, 15, or 50 mg/kg of N-(all-trans-retinoyl)-DL-leucine (RL), N-(all-trans-retinoyl)glycine…”
Get more information

O6-Methylguanine-DNA transmethylase converts O6-methylguanine thymine base pairs to guanine thymine base pairs in DNA by Toorchen, D, Lindamood, 3rd, C, Swenberg, J A, Topal, M D

“…O6-Methylguanine lesions in natural and synthetic DNAs were studied as substrates for the O6-methylguanine-DNA methyltransferase in vitro. The results indicate…”
Get more information

Dose response for DNA alkylation, [3H]thymidine uptake into DNA, and O6-methylguanine-DNA methyltransferase activity in hepatocytes of rats and mice continuously exposed to dimethylnitrosamine by LINDAMOOD, C. L. III, BEDELL, M. R, BILLINGS, K. C, DYROFF, M. C, SWENBERG, J. A

“…The objectives of these experiments were to determine N-7-methylguanine (m7Gua) and O6-methylguanine (O6mGua) concentrations in DNA, [3H]thymidine uptake into…”
Get full text

O6-alkylguanine alkyl acceptor protein activity in hepatocytes of C3H and C57BL mice during dimethylnitrosamine exposure by Lindamood, 3rd, C, Bedell, M A, Billings, K C, Dyroff, M C, Swenberg, J A

Get more information

Subchronic toxicity studies of t-butyl alcohol in rats and mice by Lindamood, 3rd, C, Farnell, D R, Giles, H D, Prejean, J D, Collins, J J, Takahashi, K, Maronpot, R R

“…The purpose of this study was to evaluate the toxicity of t-butyl alcohol, an important commodity chemical, an additive to unleaded gasoline, and a contaminant…”
Get more information

Preliminary toxicity profile of arotinoids SMR-2 and SMR-6 in male B6D2F1 mice by Lindamood, 3rd, C, Giles, H D, Hill, D L

“…Arotinoids, which are analogs of retinoic acid (RA) and retinol (RO) with the carbon skeleton in a rigid conformation, have more favorable therapeutic indices…”
Get more information

Induction of thymic lymphoma in mice administered the dideoxynucleoside ddC by Sanders, V M, Elwell, M R, Heath, J E, Collins, B J, Dunnick, J K, Rao, G N, Prejean, D, Lindamood, 3rd, C, Irwin, R D

“…Groups of 10 male and 20 female B6C3F1 mice received 0, 500, or 1000 mg/kg/day 2'3'-dideoxycytidine (ddC) by gavage for 13 weeks. At the end of the 13-week…”
Get more information

Pharmacological and toxicological properties of arotinoids SMR-2 and SMR-6 in mice by Lindamood, 3rd, C, Cope, F O, Dillehay, D L, Everson, M P, Giles, H D, Lamon, E W, McCarthy, D J, Sartin, J L, Hill, D L

“…Studies were conducted to define primary pharmacological and toxicological properties of two arotinoids, SMR-2 and SMR-6, in male B6D2F1 mice. Mice were…”
Get more information