Search Results - "Lindahl, Tomas L."

Levels of sP-selectin and hs-CRP Decrease with Dietary Intervention with Selenium and Coenzyme Q10 Combined: A Secondary Analysis of a Randomized Clinical Trial by Alehagen, Urban, Lindahl, Tomas L, Aaseth, Jan, Svensson, Erland, Johansson, Peter

“…Inflammation and oxidative stress are central in many disease states. The major anti-oxidative enzymes contain selenium. The selenium intake in Europe is low,…”
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Next generation sequencing analysis of human platelet PolyA+ mRNAs and rRNA-depleted total RNA by Kissopoulou, Antheia, Jonasson, Jon, Lindahl, Tomas L, Osman, Abdimajid

“…Platelets are small anucleate cells circulating in the blood vessels where they play a key role in hemostasis and thrombosis. Here, we compared platelet…”
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Dietary Supplementation with Selenium and Coenzyme Q10 Prevents Increase in Plasma D-Dimer While Lowering Cardiovascular Mortality in an Elderly Swedish Population by Alehagen, Urban, Aaseth, Jan, Lindahl, Tomas L., Larsson, Anders, Alexander, Jan

“…A low intake of selenium is associated with increased cardiovascular mortality. This could be reduced by supplementation with selenium and coenzyme Q10…”
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Thrombus remodelling by reversible and irreversible P2Y12 inhibitors by Tunströmer, Kjersti, Faxälv, Lars, Larsson, Pia, Lindahl, Tomas L., Boknäs, Niklas

“…Pharmacological inhibition of the platelet ADP-receptor P2Y 12 is a cornerstone in the prevention of atherothrombotic events in adult patients with acute…”
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Prasugrel 5 mg in the Very Elderly Attenuates Platelet Inhibition But Maintains Noninferiority to Prasugrel 10 mg in Nonelderly Patients by Erlinge, David, MD, PhD, Gurbel, Paul A., MD, James, Stefan, MD, PhD, Lindahl, Tomas L., MD, PhD, Svensson, Peter, MD, PhD, Ten Berg, Jurrien M., MD, PhD, Foley, David P., MBBCh, PhD, Wagner, Henrik, MD, Brown, Patricia B., BSN, RN, Luo, Junxiang, PhD, Zhou, Chunmei, MS, Moser, Brian A., MS, Jakubowski, Joseph A., PhD, Small, David S., PhD, Winters, Kenneth J., MD, Angiolillo, Dominick J., MD, PhD

“…Objectives This study assessed pharmacodynamic (PD) response to the reduced prasugrel maintenance dose of 5 mg in very elderly (VE) patients (≥75 years of…”
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The effect of tinzaparin on biomarkers in FIGO stages III-IV ovarian cancer patients undergoing neoadjuvant chemotherapy - the TABANETOC trial: study protocol for a randomized clinical multicenter trial by Karlsson, Anna, Lindahl, Gabriel, Spetz Holm, Anna-Clara, Bergmark, Karin, Dahm Kähler, Pernilla, Fekete, Boglarka, Ottander, Ulrika, Öfverman, Charlotte, Israelsson, Pernilla, Falknäs, Laila, Rosenmüller, Anders, Tiefenthal Thrane, Malena, Halili, Shefqet, Lindahl, Tomas L, Jenmalm, Maria C, Kjølhede, Preben

“…Tinzaparin, a low-molecular weight heparin (LMWH), has shown anti-neoplastic properties in animal models and in in vitro studies of human cancer cell lines…”
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Putting polyphosphates to the test: evidence against platelet-induced activation of factor XII by Faxälv, Lars, Boknäs, Niklas, Ström, Jakob O., Tengvall, Pentti, Theodorsson, Elvar, Ramström, Sofia, Lindahl, Tomas L.

“…The recent claim that stimulated platelets activate the intrinsic pathway of coagulation by the release of polyphosphates has been considered a breakthrough in…”
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Gradient-dependent inhibition of stimulatory signaling from platelet G protein-coupled receptors by Macwan, Ankit S, Boknäs, Niklas, Ntzouni, Maria P, Ramström, Sofia, Gibbins, Jonathan M, Faxälv, Lars, Lindahl, Tomas L

“…As platelet activation is an irreversible and potentially harmful event, platelet stimulatory signaling must be tightly regulated to ensure the filtering-out…”
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Caveats in studies of the physiological role of polyphosphates in coagulation by Lindahl, Tomas L, Ramström, Sofia, Boknäs, Niklas, Faxälv, Lars

“…Platelet-derived polyphosphates (polyP), stored in dense granule and released upon platelet activation, have been claimed to enhance thrombin activation of…”
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Sex differences in platelet reactivity in patients with myocardial infarction treated with triple antiplatelet therapy - results from assessing platelet activity in coronary heart disease (APACHE) by Holm, Anna, Swahn, Eva, Lawesson, Sofia Sederholm, Gustafsson, Kerstin M., Janzon, Magnus, Jonasson, Lena, Lindahl, Tomas L., Alfredsson, Joakim

“…)Several earlier studies have reported increased risk of bleeding in women with myocardial infarction, (MI) compared to men. The reasons for the observed…”
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Flow cytometry-based platelet function testing is predictive of symptom burden in a cohort of bleeders by Boknäs, Niklas, Ramström, Sofia, Faxälv, Lars, Lindahl, Tomas L.

“…Platelet function disorders (PFDs) are common in patients with mild bleeding disorders (MBDs), yet the significance of laboratory findings suggestive of a PFD…”
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A cluster of aspartic residues in the extracellular loop II of PAR 4 is important for thrombin interaction and activation of platelets by Centellas, Daniel Sánchez, Gudlur, Sushanth, Vicente-Carrillo, Alejandro, Ramström, Sofia, Lindahl, Tomas L

“…Abstract Thrombin activates platelets via proteolytic cleavage of protease-activated receptors (PARs) 1 and 4. The two PARs have distinct but complementary…”
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Left Atrial 4D Blood Flow Dynamics and Hemostasis following Electrical Cardioversion of Atrial Fibrillation by Cibis, Merih, Lindahl, Tomas L, Ebbers, Tino, Karlsson, Lars O, Carlhäll, Carl-Johan

“…Electrical cardioversion in patients with atrial fibrillation is followed by a transiently impaired atrial mechanical function, termed atrial stunning. During…”
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Protease-activated receptor 1 (PAR1) signalling desensitization is counteracted via PAR4 signalling in human platelets by Fälker, Knut, Haglund, Linda, Gunnarsson, Peter, Nylander, Martina, Lindahl, Tomas L, Grenegård, Magnus

“…PARs (protease-activated receptors) 1 and 4 belong to the family of G-protein-coupled receptors which induce both G(α12/13) and G(αq) signalling. By applying…”
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Effects of Heparin and Bivalirudin on Thrombin-Induced Platelet Activation: Differential Modulation of PAR Signaling Drives Divergent Prothrombotic Responses by Lund, Mikael, Macwan, Ankit S., Tunströmer, Kjersti, Lindahl, Tomas L., Boknäs, Niklas

“…Heparin and bivalirudin are widely used as anticoagulants in the setting of acute thrombosis. In this study, we investigated how these drugs affect the ability…”
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Inflammatory and endothelial markers during the menstrual cycle by Chaireti, Roza, Lindahl, Tomas L., Byström, Birgitta, Bremme, Katarina, Larsson, Anders

“…Background The menstrual cycle exhibits a pattern of repeated inflammatory activity. The present study aims to evaluate inflammatory and endothelial markers…”
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A novel prothrombin time method to measure all non-vitamin K-dependent oral anticoagulants (NOACs) by Lindahl, Tomas L., Arbring, Kerstin, Wallstedt, Maria, Rånby, Mats

“…Background: There is a clinical need for point-of-care (POC) methods for non-vitamin K-dependent oral anticoagulants (NOACs). We modified a routine POC…”
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Whole blood coagulation on protein adsorption-resistant PEG and peptide functionalised PEG-coated titanium surfaces by Hansson, Kenny M., Tosatti, Samuele, Isaksson, Joakim, Wetterö, Jonas, Textor, Marcus, Lindahl, Tomas L., Tengvall, Pentti

“…The aim of this study was to investigate whole blood coagulation on low blood plasma protein adsorbing surfaces. For this purpose, the polycationic graft…”
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Development of a Point of Care Lateral Flow Device for Measuring Human Plasma Fibrinogen by Dudek, Magdalena M, Lindahl, Tomas L, Killard, Anthony J

“…Fibrinogen is a major cardiovascular disease risk factor and is an independent predictor of coronary heart disease and stroke. Normal reference levels are…”
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IN VITRO EFFECTS OF ANTIPSYCHOTICS ON HUMAN PLATELET ADHESION AND AGGREGATION AND PLASMA COAGULATION by Axelsson, Stina, Hägg, Staffan, Eriksson, Andreas C, Lindahl, Tomas L, Whiss, Per A

“…SUMMARY 1 Several studies suggest an association between venous thromboembolism and the use of antipsychotic drugs, especially clozapine, but the biological…”
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