Search Results - "Linck, Bettina"

Functional comparison of the three isoforms of the Na+/Ca2+ exchanger (NCX1, NCX2, NCX3) by Linck, B, Qiu, Z, He, Z, Tong, Q, Hilgemann, D W, Philipson, K D

“…Three distinct mammalian Na+/Ca2+ exchangers have been cloned: NCX1, NCX2, and NCX3. We have undertaken a detailed functional comparison of these three…”
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Regional Expression of Protein Phosphatase Type 1 and 2A Catalytic Subunit Isoforms in the Human Heart by Lüss, Hartmut, Klein-Wiele, Oliver, Boknı́k, Peter, Herzig, Stefan, Knapp, Jörg, Linck, Bettina, Müller, Frank U., Scheld, Hans H., Schmid, Christof, Schmitz, Wilhelm, Neumann, Joachim

“…In mammalian species, including man, the duration of myocardial contraction is shorter in atria than ventricles. Total contraction time depends at least in…”
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Role of protein phosphatases in regulation of cardiac inotropy and relaxation by Bokník, P, Khorchidi, S, Bodor, G S, Huke, S, Knapp, J, Linck, B, Lüss, H, Müller, F U, Schmitz, W, Neumann, J

“…We studied the effects of the protein phosphatase (PP) inhibitor cantharidin (Cant) on time parameters and force of contraction (FOC) in isometrically…”
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Long-term beta adrenoceptor-mediated alteration in contractility and expression of phospholamban and sarcoplasmic reticulum Ca(++)-ATPase in mammalian ventricle by Linck, B, Bokník, P, Baba, H A, Eschenhagen, T, Haverkamp, U, Jäckel, E, Jones, L R, Kirchhefer, U, Knapp, J, Läer, S, Müller, F U, Schmitz, W, Scholz, H, Syska, A, Vahlensieck, U, Neumann, J

“…We studied the influence of prolonged administration of the beta adrenoceptor agonist isoproterenol on contractile parameters and expression of sarcoplasmic…”
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Cantharidin enhances norepinephrine-induced vasoconstriction in an endothelium-dependent fashion by Knapp, J, Bokník, P, Linck, B, Lüss, H, Müller, F U, Petertönjes, L, Schmitz, W, Neumann, J

“…In this study we characterized the effects of the protein phosphatase (PP) type 1 and type 2A inhibitor cantharidin (Cant) and its structural analogs…”
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The protein phosphatase inhibitor cantharidin alters vascular endothelial cell permeability by Knapp, J, Bokník, P, Lüss, I, Huke, S, Linck, B, Lüss, H, Müller, F U, Müller, T, Nacke, P, Noll, T, Piper, H M, Schmitz, W, Vahlensieck, U, Neumann, J

“…In this study, we characterized the effects of the protein phosphatases type 1 (PP 1) and type 2A (PP 2A) inhibitor cantharidin in endothelial cells. We…”
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Functional studies in atrium overexpressing A 1 ‐adenosine receptors by Neumann, Joachim, Vahlensieck, Ute, Boknik, Peter, Linck, Bettina, Lüss, Hartmut, Müller, Frank U, Matherne, G Paul, Schmitz, Wilhelm

“…Adenosine and the A 1 ‐adenosine receptor agonist R‐PIA, exerted a negative inotropic effect in isolated, electrically driven left atria of wild‐type mice. In…”
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Increased Expression of Cardiac Phosphatases in Patients with End-stage Heart Failure by Neumann, Joachim, Eschenhagen, Thomas, Jones, Larry R., Linck, Bettina, Schmitz, Wilhelm, Scholz, Hasso, Zimmermann, Norbert

“…Type 1 phosphatase activity was increased in membrane vesicles from failing human ventricles compared with non-failing controls. Likewise, expression of the…”
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Expression of Cardiac Calcium Regulatory Proteins in Atrium v Ventricle in Different Species by Lüss, Iva, Boknik, Peter, Jones, Larry R., Kirchhefer, Uwe, Knapp, Jörg, Linck, Bettina, Lüss, Hartmut, Meissner, Andreas, Müller, Frank U., Schmitz, Wilhelm, Vahlensieck, Ute, Neumann, Joachim

“…The duration of contraction in isolated electrically driven preparations from atrium and ventricle of mouse, rat, rabbit, guinea-pig and dog was consistently…”
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Messenger RNA expression and immunological quantification of phospholamban and SR-Ca2+-ATPase in failing and nonfailing human hearts by Linck, Bettina, Bokník, Peter, Eschenhagen, Thomas, Müller, Frank U., Neumann, Joachim, Nose, Monika, Jones, Larry R., Schmitz, Wilhelm, Scholz, Hasso

“…Objectives: Human heart failure is associated with prolonged relaxation and prolonged Ca2+ transients which indicates an impaired function of the sarcoplasmic…”
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The Inhibitory Effect of Bupivacaine on Prostaglandin E2 (EP1) Receptor Functioning: Mechanism of Action by Hönemann, Christian W., Heyse, Thomas J., Möllhoff, Thomas, Hahnenkamp, Klaus, Berning, Sascha, Hinder, Frank, Linck, Bettina, Schmitz, Wilhelm, van Aken, Hugo

“…Prostaglandin E2 receptors, subtype EP1 (PGE2EP1) have been linked to several physiologic responses, such as fever, inflammation, and mechanical hyperalgesia…”
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Enhanced protein phosphorylation in hypertensive hypertrophy by BOKNIK, Peter, HEINROTH-HOFFMANN, Ingrid, KIRCHHEFER, Uwe, KNAPP, Jörg, LINCK, Bettina, LÜSS, Hartmut, MÜLLER, Thorsten, SCHMITZ, Wilhelm, BRODDE, Otto-Erich, NEUMANN, Joachim

“…Chronic pressure overload in spontaneously hypertensive rats (SHR) is accompanied by heart hypertrophy and signs of heart failure. Since there is growing…”
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Protein phosphatase activity is increased in a rat model of long-term beta-adrenergic stimulation by Bokník, P, Fockenbrock, M, Herzig, S, Knapp, J, Linck, B, Lüss, H, Müller, F U, Müller, T, Schmitz, W, Schröder, F, Neumann, J

“…We tested the hypothesis that altered phosphorylation of Ca2+ regulatory proteins contributes to contractile anomalies in cardiac hypertrophy. Cardiac…”
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Activation and inactivation of cAMP-response element-mediated gene transcription in cardiac myocytes by MÜLLER, Frank U, BOKNIK, Peter, KNAPP, Jörg, LINCK, Bettina, LÜSS, Hartmut, NEUMANN, Joachim, SCHMITZ, Wilhelm

“…Chronic beta-adrenergic stimulation of the cAMP-dependent signalling pathway is implicated in functionally relevant expressional changes in congestive heart…”
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Regional expression of phospholamban in the human heart by BOKNIK, P, UNKEL, C, VAHLENSIECK, U, ZIMMERMANN, N, JONES, L. R, NEUMANN, J, KIRCHHEFER, U, KLEIDEITER, U, KLEIN-WIELE, O, KNAPP, J, LINCK, B, LÜSS, H, MÜLLER, F. U, SCHMITZ, W

“…Several independent lines of evidence indicate that phospholamban (PLB) expression correlates positively with depression of force of contraction and duration…”
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Messenger RNA expression and immunological quantification of phospholamban and SR-Ca2+-ATPase in failing and nonfailing human hearts by Linck, Bettina, Schmitz, Wilhelm

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Biochemical mechanism(s) of stunning in conscious dogs by Lüss, H, Meissner, A, Rolf, N, Van Aken, H, Bokník, P, Kirchhefer, U, Knapp, J, Läer, S, Linck, B, Lüss, I, Müller, F U, Neumann, J, Schmitz, W

“…The mechanism(s) underlying contractile dysfunction in cardiac stunning is not completely understood. The expression and/or the phosphorylation state of…”
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Modulation of Xenopus laevis Ca-activated Cl currents by protein kinase C and protein phosphatases: Implications for studies of anesthetic mechanisms by HAHNENKAMP, Klaus, DURIEUX, Marcel E, VAN AKEN, Hugo, BERNING, Sascha, HEYSE, Thomas J, HONEMANN, Christian W, LINCK, Bettina

“…Ca-activated Cl currents (I(Cl(Ca))) are used frequently as reporters in functional studies of anesthetic effects on G protein-coupled receptors using Xenopus…”
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Functional properties of the rat phosphatase 1[alpha] promoter by Linck, Bettina, Bokník, Peter, Knapp, Jörg, Kikuchi, Kunimi, Lüss, Hartmut, Müller, Frank U, Nomoto, Ken, Neumann, Joachim, Schmitz, Wilhelm

“…The aim of this study was to investigate the functional properties of the promoter of the protein phosphatase 1α catalytic subunit. Luciferase plasmids with…”
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Functional properties of transgenic mouse hearts overexpressing both calsequestrin and the Na(+)-Ca(2+) exchanger by Linck, B, Bokník, P, Huke, S, Kirchhefer, U, Knapp, J, Lüss, H, Müller, F U, Neumann, J, Tanriseven, Z, Vahlensieck, U, Baba, H A, Jones, L R, Philipson, K D, Schmitz, W

“…Overexpression of calsequestrin (CSQ) induces severe cardiac hypertrophy, whereas overexpression of Na(+)-Ca(2+) exchanger (NCX) does not affect cardiac…”
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