Search Results - "Lin, Zuojun"

Human-induced pluripotent stem cell-derived cardiomyocytes exhibit temporal changes in phenotype by Ivashchenko, Christine Y, Pipes, Gordon C, Lozinskaya, Irina M, Lin, Zuojun, Xiaoping, Xu, Needle, Saul, Grygielko, Eugene T, Hu, Erding, Toomey, John R, Lepore, John J, Willette, Robert N

“…Human-induced pluripotent stem cell-derived cardiomyocytes (hiPS-CMs) have been recently derived and are used for basic research, cardiotoxicity assessment,…”
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Systemic activation of the transient receptor potential vanilloid subtype 4 channel causes endothelial failure and circulatory collapse: Part 2 by Willette, Robert N, Bao, Weike, Nerurkar, Sandhya, Yue, Tian-Li, Doe, Chris P, Stankus, Gerald, Turner, Gregory H, Ju, Haisong, Thomas, Heath, Fishman, Cindy E, Sulpizio, Anthony, Behm, David J, Hoffman, Sandra, Lin, Zuojun, Lozinskaya, Irina, Casillas, Linda N, Lin, Min, Trout, Robert E Lee, Votta, Bartholomew J, Thorneloe, Kevin, Lashinger, Erin S R, Figueroa, David J, Marquis, Robert, Xu, Xiaoping

“…The transient receptor potential (TRP) vanilloid subtype 4 (V4) is a nonselective cation channel that exhibits polymodal activation and is expressed in the…”
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Mallotoxin is a novel human ether-a-go-go-related gene (hERG) potassium channel activator by Zeng, Haoyu, Lozinskaya, Irina M, Lin, Zuojun, Willette, Robert N, Brooks, David P, Xu, Xiaoping

“…Human ether-a-go-go-related gene (hERG) encodes a rapidly activating delayed rectifier potassium channel that plays important roles in cardiac action potential…”
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N-((1S)-1-{[4-((2S)-2-{[(2,4-dichlorophenyl)sulfonyl]amino}-3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide (GSK1016790A), a novel and potent transient receptor potential vanilloid 4 channel agonist induces urinary bladder contraction and hyperactivity: Part I by Thorneloe, Kevin S, Sulpizio, Anthony C, Lin, Zuojun, Figueroa, David J, Clouse, Angela K, McCafferty, Gerald P, Chendrimada, Tim P, Lashinger, Erin S R, Gordon, Earl, Evans, Louise, Misajet, Blake A, Demarini, Douglas J, Nation, Josephine H, Casillas, Linda N, Marquis, Robert W, Votta, Bartholomew J, Sheardown, Steven A, Xu, Xiaoping, Brooks, David P, Laping, Nicholas J, Westfall, Timothy D

“…The transient receptor potential (TRP) vanilloid 4 (TRPV4) member of the TRP superfamily has recently been implicated in numerous physiological processes. In…”
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2-[2-(3,4-dichloro-phenyl)-2,3-dihydro-1H-isoindol-5-ylamino]-nicotinic acid (PD-307243) causes instantaneous current through human ether-a-go-go-related gene potassium channels by Gordon, Earl, Lozinskaya, Irina M, Lin, Zuojun, Semus, Simon F, Blaney, Frank E, Willette, Robert N, Xu, Xiaoping

“…Long and short QT syndromes associated with loss and gain of human ether-a-go-go-related gene (hERG) channel activity, respectively, can cause life-threatening…”
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Characterization of Small Molecule TRPC3 and TRPC6 agonist and Antagonists by Xu, Xiaoping, Lozinskaya, Irina, Costell, Melissa, Lin, Zuojun, Ball, Jennifer A., Bernard, Roberta, Behm, David J., Marino, Joseph P., Schnackenberg, Christine G.

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Functional TRPV4 channels and an absence of capsaicin-evoked currents in freshly-isolated, guinea-pig urothelial cells by Xu, Xiaoping, Gordon, Earl A., Lin, Zuojun, Lozinskaya, Irina M., Chen, Yifeng, Thorneloe, Kevin S.

“…Previously we have shown that the transient receptor potential vanilloid 4 (TRPV4) channel regulates urinary bladder function, and that TRPV4 is expressed in…”
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1-[1-Hexyl-6-(methyloxy)-1H-indazol-3-yl]-2-methyl-1-propanone, a potent and highly selective small molecule blocker of the large-conductance voltage-gated and calcium-dependent K+ channel by Zeng, Haoyu, Gordon, Earl, Lin, Zuojun, Lozinskaya, Irina M, Willette, Robert N, Xu, Xiaoping

“…The large-conductance voltage-gated and calcium-dependent K(+) (BK) channels are widely distributed and play important physiological roles. Commonly used BK…”
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Acetic acid opens large-conductance Ca2+-activated K+ channels in guinea pig detrusor smooth muscle cells by GHATTA, Srinivas, LOZINSKAYA, Irina, ZUOJUN LIN, GORDON, Earl, WILLETTE, Robert N, BROOKS, David P, XIAOPING XU

“…Acetic acid was found to have actions on urinary bladder smooth muscle in our routine ion channel screening assays. Numerous studies have examined the…”
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Blockade of bepridil on IA and IK in acutely isolated hippocampal CA1 neurons by Hu, Huijuan, Yang, Dongmei, Lin, Zuojun, Wu, Caihong, Zhou, Pei'ai, Dai, Dezai

“…The effects of bepridil, an antianginal agent with antiarrhythmic action, on voltage-dependent K + currents in the CA1 pyramidal neurons acutely isolated from…”
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Characterizing the role of Thr352 in the inhibition of the large conductance Ca2+-activated K+ channels by 1-[1-hexyl-6-(methyloxy)-1H-indazol-3-yl]-2-methyl-1-propanone by Gordon, Earl, Semus, Simon F, Lozinskaya, Irina M, Lin, Zuojun, Xu, Xiaoping

“…Large conductance Ca(2+)-activated K(+) (BK) channels are known to be regulated by both intracellular Ca(2+) and voltage. Although BK channel modulators have…”
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A critical GxxxA motif in the γ6 calcium channel subunit mediates its inhibitory effect on Cav3.1 calcium current by Lin, Zuojun, Witschas, Katja, Garcia, Thomas, Chen, Ren‐Shiang, Hansen, Jared P., Sellers, Zachary M., Kuzmenkina, Elza, Herzig, Stefan, Best, Philip M.

“…The eight members of the calcium channel γ subunit family are integral membrane proteins that regulate the expression and behaviour of voltage and ligand gated…”
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A critical GxxxA motif in the gamma sub(6) calcium channel subunit mediates its inhibitory effect on Cav3.1 calcium current by Lin, Zuojun, Witschas, Katja, Garcia, Thomas, Chen, Ren-Shiang, Hansen, Jared P, Sellers, Zachary M, Kuzmenkina, Elza, Herzig, Stefan, Best, Philip M

“…The eight members of the calcium channel gamma subunit family are integral membrane proteins that regulate the expression and behaviour of voltage and ligand…”
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A critical GxxxA motif in the γ6 calcium channel subunit mediates its inhibitory effect on Cav3.1 calcium current by Zuojun Lin, Katja Witschas, Thomas Garcia, Ren-Shiang Chen, Jared P. Hansen, Zachary M. Sellers, Elza Kuzmenkina, Stefan Herzig, Philip M. Best

“…The eight members of the calcium channel γ subunit family are integral membrane proteins that regulate the expression and behaviour of voltage and ligand…”
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Acetic acid opens large-conductance Ca 2+-activated K + channels in guinea pig detrusor smooth muscle cells by Ghatta, Srinivas, Lozinskaya, Irina, Lin, Zuojun, Gordon, Earl, Willette, Robert N., Brooks, David P., Xu, Xiaoping

“…Acetic acid was found to have actions on urinary bladder smooth muscle in our routine ion channel screening assays. Numerous studies have examined the…”
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A critical GxxxA motif in the γ 6 calcium channel subunit mediates its inhibitory effect on Cav3.1 calcium current by Lin, Zuojun, Witschas, Katja, Garcia, Thomas, Chen, Ren‐Shiang, Hansen, Jared P., Sellers, Zachary M., Kuzmenkina, Elza, Herzig, Stefan, Best, Philip M.

“…The eight members of the calcium channel γ subunit family are integral membrane proteins that regulate the expression and behaviour of voltage and ligand gated…”
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Abstract 1289: Activation of the Transient Receptor Potential V4 Channel Causes Cardiovascular Collapse Mediated by Endothelial Failure by Willette, Robert N, Bao, Weike, Nerurkar, Sandhya, Yue, Tian-li, Doe, Chris P, Stankus, Gerald, Ju, Haisong, Bentley, Ross, Sulpizio, Anthony, Behm, David, Sandra, Hoffman, Maniscalco, Kristeen, Lin, Zuojun, Linda, Casillas N, Lin, Min, Trout, Robert E, Votta, Bartholomew J, Marquis, Robert W, Xiaoping, Xu

“…Abstract only Transient receptor potential V4 (TRPV4), is an osmo/mechano-sensitive ligand-gated non-selective cationic channel that contributes to…”
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The calcium channel γ6 subunit analysis of function and determination of a sequence motif critical for its effect by Lin, Zuojun

“…The auxiliary γ6 subunit of voltage dependent calcium channels is known to decrease calcium current density when co-expressed with the pore forming Cav3.1…”
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A critical GxxxA motif in the gamma6 calcium channel subunit mediates its inhibitory effect on Cav3.1 calcium current by Lin, Zuojun, Witschas, Katja, Garcia, Thomas, Chen, Ren-Shiang, Hansen, Jared P, Sellers, Zachary M, Kuzmenkina, Elza, Herzig, Stefan, Best, Philip M

“…The eight members of the calcium channel gamma subunit family are integral membrane proteins that regulate the expression and behaviour of voltage and ligand…”
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Intent Pattern Recognition of Lower-limb Motion Based on Mechanical Sensors by Liu, Zuojun, Lin, Wei, Geng, Yanli, Yang, Peng

“…Based on the regularity nature of lower-limb motion,an intent pattern recognition approach for above-knee prosthesis is proposed in this paper. To remedy the…”
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