Search Results - "Lin, Yung‐Yao"

Comparative epigenetic analysis of tumour initiating cells and syngeneic EPSC-derived neural stem cells in glioblastoma by Vinel, Claire, Rosser, Gabriel, Guglielmi, Loredana, Constantinou, Myrianni, Pomella, Nicola, Zhang, Xinyu, Boot, James R., Jones, Tania A., Millner, Thomas O., Dumas, Anaelle A., Rakyan, Vardhman, Rees, Jeremy, Thompson, Jamie L., Vuononvirta, Juho, Nadkarni, Suchita, El Assan, Tedani, Aley, Natasha, Lin, Yung-Yao, Liu, Pentao, Nelander, Sven, Sheer, Denise, Merry, Catherine L. R., Marelli-Berg, Federica, Brandner, Sebastian, Marino, Silvia

“…Epigenetic mechanisms which play an essential role in normal developmental processes, such as self-renewal and fate specification of neural stem cells (NSC)…”
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A new patient‐derived iPSC model for dystroglycanopathies validates a compound that increases glycosylation of α‐dystroglycan by Kim, Jihee, Lana, Beatrice, Torelli, Silvia, Ryan, David, Catapano, Francesco, Ala, Pierpaolo, Luft, Christin, Stevens, Elizabeth, Konstantinidis, Evangelos, Louzada, Sandra, Fu, Beiyuan, Paredes‐Redondo, Amaia, Chan, AW Edith, Yang, Fengtang, Stemple, Derek L, Liu, Pentao, Ketteler, Robin, Selwood, David L, Muntoni, Francesco, Lin, Yung‐Yao

“…Dystroglycan, an extracellular matrix receptor, has essential functions in various tissues. Loss of α‐dystroglycan‐laminin interaction due to defective…”
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Investigating the role of dystrophin isoform deficiency in motor function in Duchenne muscular dystrophy by Chesshyre, Mary, Ridout, Deborah, Hashimoto, Yasumasa, Ookubo, Yoko, Torelli, Silvia, Maresh, Kate, Ricotti, Valeria, Abbott, Lianne, Gupta, Vandana Ayyar, Main, Marion, Ferrari, Giulia, Kowala, Anna, Lin, Yung‐Yao, Tedesco, Francesco Saverio, Scoto, Mariacristina, Baranello, Giovanni, Manzur, Adnan, Aoki, Yoshitsugu, Muntoni, Francesco

“…Background Duchenne muscular dystrophy (DMD) is caused by DMD mutations leading to dystrophin loss. Full‐length Dp427 is the primary dystrophin isoform…”
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The functional O-mannose glycan on α-dystroglycan contains a phospho-ribitol primed for matriglycan addition by Praissman, Jeremy L, Willer, Tobias, Sheikh, M Osman, Toi, Ants, Chitayat, David, Lin, Yung-Yao, Lee, Hane, Stalnaker, Stephanie H, Wang, Shuo, Prabhakar, Pradeep Kumar, Nelson, Stanley F, Stemple, Derek L, Moore, Steven A, Moremen, Kelley W, Campbell, Kevin P, Wells, Lance

“…Multiple glycosyltransferases are essential for the proper modification of alpha-dystroglycan, as mutations in the encoding genes cause congenital/limb-girdle…”
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Surgical and Functional Outcomes of Robotic-Assisted Radical Prostatectomy in Patients with Previous Transurethral Resection of the Prostate by Chen, Sih-Han, Wu, Chun-Hsien, Wu, Richard, Kuo, Wade, Lee, Yen-Hsi, Li, Ryh-Chyr, Lin, Yung-Yao, Lin, Victor

“…Purpose: The purpose of this study was to assess the surgical and functional outcomes of robotic-assisted radical prostatectomy (RARP) in patients with…”
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Urinary schistosomiasis: Schistosoma haematobium infection diagnosed by histopathology by Lin, Yung-Yao, Lin, Victor, Chang, I-Wei

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Muscle diseases in the zebrafish by Lin, Yung-Yao

“…Abstract Animal models in biomedical research are important for understanding the pathological mechanisms of human diseases at a molecular and cellular level…”
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Missense mutations in β-1,3-N-acetylglucosaminyltransferase 1 (B3GNT1) cause Walker-Warburg syndrome by Buysse, Karen, Riemersma, Moniek, Powell, Gareth, van Reeuwijk, Jeroen, Chitayat, David, Roscioli, Tony, Kamsteeg, Erik-Jan, van den Elzen, Christa, van Beusekom, Ellen, Blaser, Susan, Babul-Hirji, Riyana, Halliday, William, Wright, Gavin J, Stemple, Derek L, Lin, Yung-Yao, Lefeber, Dirk J, van Bokhoven, Hans

“…Several known or putative glycosyltransferases are required for the synthesis of laminin-binding glycans on alpha-dystroglycan (αDG), including POMT1, POMT2,…”
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Mutations in GDP-Mannose Pyrophosphorylase B Cause Congenital and Limb-Girdle Muscular Dystrophies Associated with Hypoglycosylation of α-Dystroglycan by Carss, Keren J., Stevens, Elizabeth, Foley, A. Reghan, Cirak, Sebahattin, Riemersma, Moniek, Torelli, Silvia, Hoischen, Alexander, Willer, Tobias, van Scherpenzeel, Monique, Moore, Steven A., Messina, Sonia, Bertini, Enrico, Bönnemann, Carsten G., Abdenur, Jose E., Grosmann, Carla M., Kesari, Akanchha, Punetha, Jaya, Quinlivan, Ros, Waddell, Leigh B., Young, Helen K., Wraige, Elizabeth, Yau, Shu, Brodd, Lina, Feng, Lucy, Sewry, Caroline, MacArthur, Daniel G., North, Kathryn N., Hoffman, Eric, Stemple, Derek L., Hurles, Matthew E., van Bokhoven, Hans, Campbell, Kevin P., Lefeber, Dirk J., Lin, Yung-Yao, Muntoni, Francesco

“…Congenital muscular dystrophies with hypoglycosylation of α-dystroglycan (α-DG) are a heterogeneous group of disorders often associated with brain and eye…”
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Mutations in B3GALNT2 Cause Congenital Muscular Dystrophy and Hypoglycosylation of α-Dystroglycan by Stevens, Elizabeth, Carss, Keren J., Cirak, Sebahattin, Foley, A. Reghan, Torelli, Silvia, Willer, Tobias, Tambunan, Dimira E., Yau, Shu, Brodd, Lina, Sewry, Caroline A., Feng, Lucy, Haliloglu, Goknur, Orhan, Diclehan, Dobyns, William B., Enns, Gregory M., Manning, Melanie, Krause, Amanda, Salih, Mustafa A., Walsh, Christopher A., Hurles, Matthew, Campbell, Kevin P., Manzini, M. Chiara, Stemple, Derek, Lin, Yung-Yao, Muntoni, Francesco

“…Mutations in several known or putative glycosyltransferases cause glycosylation defects in α-dystroglycan (α-DG), an integral component of the dystrophin…”
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Zebrafish Fukutin family proteins link the unfolded protein response with dystroglycanopathies by LIN, Yung-Yao, WHITE, Richard J, TORELLI, Silvia, CIRAK, Sebahattin, MUNTONI, Francesco, STEMPLE, Derek L

“…Allelic mutations in putative glycosyltransferase genes, fukutin and fukutin-related protein (fkrp), lead to a wide range of muscular dystrophies associated…”
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3D Compartmentalised Human Pluripotent Stem Cell-derived Neuromuscular Co-cultures by Harley, Peter, Paredes-Redondo, Amaia, Grenci, Gianluca, Viasnoff, Virgile, Lin, Yung-Yao, Lieberam, Ivo

“…Human neuromuscular diseases represent a diverse group of disorders with unmet clinical need, ranging from muscular dystrophies, such as Duchenne muscular…”
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Optogenetic modeling of human neuromuscular circuits in Duchenne muscular dystrophy with CRISPR and pharmacological corrections by Paredes-Redondo, Amaia, Harley, Peter, Maniati, Eleni, Ryan, David, Louzada, Sandra, Meng, Jinhong, Kowala, Anna, Fu, Beiyuan, Yang, Fengtang, Liu, Pentao, Marino, Silvia, Pourquié, Olivier, Muntoni, Francesco, Wang, Jun, Lieberam, Ivo, Lin, Yung-Yao

“…Duchenne muscular dystrophy (DMD) is caused by gene mutations leading to skeletal muscle weakness and wasting. Dystrophin is enriched at the neuromuscular…”
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Nuclear Respiratory Factor 1 Overexpression Inhibits Proliferation and Migration of PC3 Prostate Cancer Cells by WU, CHUN-HSIEN, HSIEH, PEI-FANG, LEE, YEN-HSI, KUO, WADE WEI-TING, WU, RICHARD CHEN-YU, LIN, YUNG-YAO, HUNG, CHIH-HSIN, HSIEH, MING-LIN, PANG, SEE-TONG, YANG, YU-LIN, LIN, VICTOR C.

“…Background/Aim: The role of nuclear respiratory factor 1 (NRF1) on the prostate cancer progression is controversial. We aimed to investigate the effect of NRF1…”
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Molecular dissection of Drosophila Prickle isoforms distinguishes their essential and overlapping roles in planar cell polarity by Lin, Yung-Yao, Gubb, David

“…Prickle-Spiny-Legs (Pk) is an essential component of the planar cell polarity (PCP) pathway, together with Frizzled (Fz) and Dishevelled (Dsh). A role for Pk…”
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GPX2 underexpression indicates poor prognosis in patients with urothelial carcinomas of the upper urinary tract and urinary bladder by Chang, I-Wei, Lin, Victor Chia-Hsiang, Hung, Chih-Hsin, Wang, Hua-Pin, Lin, Yung-Yao, Wu, Wen-Jeng, Huang, Chun-Nung, Li, Ching-Chia, Li, Wei-Ming, Wu, Jui-Yu, Li, Chien-Feng

“…Purpose Oxidative stress is believed to be one of the important etiologies in carcinogenesis that has not been systemically investigated in urothelial…”
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220th ENMC workshop: Dystroglycan and the dystroglycanopathies Naarden, The Netherlands, 27–29 May 2016 by Brown, Susan C., Winder, Steve J., Bevan, Neil, Bevan, Lyndsey, Brown, Sue, van Bokhoven, Hans, Campbell, Kevin, Cirak, Sebahattin, Cisneros, Bulmaro, Colognato, Holly, Hohenester, Erhard, Lefeber, Dirk, Liljedahl, Monika, Lin, Yung-Yao, Lu, Qi, Seta, Natalie, Lefeber, Dirk J., Honenester, Erherd, Shcherbata, Halyna, Straub, Volker, Winder, Steve

“…•Review of clinical phenotypes associated with the dystroglycanopathies.•Discussion of current animal models and their contribution to understanding the…”
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Using R.E.N.A.L. nephrometry and preoperative aspects and dimensions employed for anatomical classification to evaluate perioperative outcomes of renal tumors greater than 4 cm in patients who underwent minimally invasive partial nephrectomy in a single center by Mai, Hsing-Chia, Wu, Chun-Hsien, Lin, Yung-Yao, Kuo, Wade, Lee, Yen-Hsi, Li, Ryh-Chyr, Wu, Richard, Lin, Victor

“…Purpose: The R.E.N.A.L. (radius, exophytic/endophytic tumor properties, nearness of tumor to deepest portion of collecting system or sinus, anterior/posterior…”
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Endoureterotomy for ureteral stricture using a thulium laser: Preliminary experience by Chiang, Pai-Kai, Lin, Yung-Yao, Tsai, Wei-Kung, Lin, Wen-Chou, Hsu, Jong-Ming

“…We report our preliminary experience with thulium-laser endoureterotomy for managing ureteral strictures. From October 2008 to September 2009, 12 patients…”
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CRISPR-mediated correction of skeletal muscle Ca2+ handling in a novel DMD patient-derived pluripotent stem cell model by Morera, Cristina, Kim, Jihee, Paredes-Redondo, Amaia, Nobles, Muriel, Rybin, Denis, Moccia, Robert, Kowala, Anna, Meng, Jinhong, Garren, Seth, Liu, Pentao, Morgan, Jennifer E, Muntoni, Francesco, Christoforou, Nicolas, Owens, Jane, Tinker, Andrew, Lin, Yung-Yao

“…•Generation of an in vitro model of skeletal muscle using an isogenic pair of DMD patient-derived and CRISPR-corrected pluripotent stem cell (PSC)…”
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