Search Results - "Lin, Xiukun"

Apoptotic Pathway as the Therapeutic Target for Anticancer Traditional Chinese Medicines by An, Weixiao, Lai, Honglin, Zhang, Yangyang, Liu, Minghua, Lin, Xiukun, Cao, Shousong

“…Cancer is a leading cause of morbidity and mortality worldwide. Apoptosis is a process of programmed cell death and it plays a vital role in human development…”
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Bromophenols in marine algae and their bioactivities by Liu, Ming, Hansen, Poul Erik, Lin, Xiukun

“…Marine algae contain various bromophenols that have been shown to possess a variety of biological activities, including antioxidant, antimicrobial, anticancer,…”
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Oleanolic acid suppresses aerobic glycolysis in cancer cells by switching pyruvate kinase type M isoforms by Liu, Jia, Wu, Ning, Ma, Leina, Liu, Ming, Liu, Ge, Zhang, Yuyan, Lin, Xiukun

“…Warburg effect, one of the hallmarks for cancer cells, is characterized by metabolic switch from mitochondrial oxidative phosphorylation to aerobic glycolysis…”
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Progress of Bromophenols in Marine Algae from 2011 to 2020: Structure, Bioactivities, and Applications by Dong, Hui, Dong, Songtao, Erik Hansen, Poul, Stagos, Dimitrios, Lin, Xiukun, Liu, Ming

“…Marine algae contain various bromophenols that have been shown to possess a variety of biological activities, including antiradical, antimicrobial, anticancer,…”
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Active fraction of clove induces apoptosis via PI3K/Akt/mTOR-mediated autophagy in human colorectal cancer HCT-116 cells by Liu, Minghua, Zhao, Ge, Zhang, Dan, An, Weixiao, Lai, Honglin, Li, Xiaofang, Cao, Shousong, Lin, Xiukun

“…Previous studies by our group have demonstrated that extract of clove exhibits potent anticancer effects in vitro and in vivo. In the present study, the effect…”
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Marine Bromophenol Bis(2,3,6-Tribromo-4,5-Dihydroxybenzyl)ether Inhibits Angiogenesis in Human Umbilical Vein Endothelial Cells and Reduces Vasculogenic Mimicry in Human Lung Cancer A549 Cells by Dong, Songtao, Chen, Zhongyuan, Wang, Li, Liu, Yankai, Stagos, Dimitrios, Lin, Xiukun, Liu, Ming

“…Angiogenesis, including the growth of new capillary blood vessels from existing ones and the malignant tumors cells formed vasculogenic mimicry, is quite…”
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Role of microRNA-26b in glioma development and its mediated regulation on EphA2 by Wu, Ning, Zhao, Xiangzhong, Liu, Ming, Liu, Haizhou, Yao, Weicheng, Zhang, Yuyan, Cao, Shousong, Lin, Xiukun

“…MicroRNAs (miRNAs) are short, non-coding RNAs that regulate the expression of multiple target genes. Deregulation of miRNAs is common in human tumorigenesis…”
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Oleanolic acid arrests cell cycle and induces apoptosis via ROS-mediated mitochondrial depolarization and lysosomal membrane permeabilization in human pancreatic cancer cells by Wei, Jianteng, Liu, Ming, Liu, Haizhou, Wang, Hui, Wang, Fengxia, Zhang, Yuyan, Han, Lijun, Lin, Xiukun

“…ABSTRACT Oleanolic acid (OA), a pentacyclic triterpenoid, exhibits potential anti‐tumor activity against many tumor cell lines. This study aims to examine the…”
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Aqueous extract of clove inhibits tumor growth by inducing autophagy through AMPK/ULK pathway by Li, Cong, Xu, Huanli, Chen, Xiaoliang, Chen, Jijun, Li, Xiao, Qiao, Gan, Tian, Ye, Yuan, Ru, Su, Shuonan, Liu, Xiaohui, Lin, Xiukun

“…Cloves (Syzygium aromaticum), a traditional Chinese medicinal herb, displays broad biological activity. In the present study, the aqueous extract of clove…”
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Marine bromophenol bis(2,3-dibromo-4,5-dihydroxybenzyl) ether, induces mitochondrial apoptosis in K562 cells and inhibits topoisomerase I in vitro by Liu, Ming, Zhang, Wei, Wei, Jianteng, Qiu, Lin, Lin, Xiukun

“…► BDDE exhibits apoptotic activity in K562 cells via mitochondrial pathway. ► BDDE inhibits the activity of topoisomerase I. ► BDDE does not stimulate the…”
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LAIR1 drives glioma progression by nuclear focal adhesion kinase dependent expressions of cyclin D1 and immunosuppressive chemokines/cytokines by Wei, Xiaoqian, Pan, Shushan, Wang, Zirui, Chen, Jieru, Lu, Li, Cao, Qizhi, Song, Shuling, Zhang, Huachang, Liu, Xiaohui, Qu, Xianjun, Lin, Xiukun, Xu, Huanli

“…Leukocyte-associated immunoglobulin-like receptor-1 (LAIR1), an immune receptor containing immunoreceptor tyrosine-based inhibiory motifs (ITIMs), has emerged…”
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Teratogenic jervine increases the activity of doxorubicin in MCF-7/ADR cells by inhibiting ABCB1 by Liu, Ming, Lu, Xuxiu, Zhang, Jinman, Zhao, Xingzeng, Zhang, Wei, Lin, Xiukun

“…Jervine is a natural teratogenic compound isolated from Veratrum californicum. In this study, for the first time, we revealed a novel activity of jervine in…”
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Antitumor Effects and the Compatibility Mechanisms of Herb Pair Scleromitrion diffusum (Willd.) R. J. Wang- Sculellaria barbata D. Don by Lu, Li, Zhan, Sheng, Liu, Xiaohui, Zhao, Xin, Lin, Xiukun, Xu, Huanli

“…Herb pair (Willd.) R. J. Wang (HD) and D. Don (SB) has been most frequently used for cancer treatment in traditional Chinese medicine. This study aimed to…”
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Zinc-Doped Copper Oxide Nanocomposites Inhibit the Growth of Pancreatic Cancer by Inducing Autophagy Through AMPK/mTOR Pathway by Li, Xiao, Xu, Huanli, Li, Cong, Qiao, Gan, Farooqi, Ammad Ahmad, Gedanken, Aharon, Liu, Xiaohui, Lin, Xiukun

“…Zinc doped copper oxide nanocomposites (Zn-CuO NPs) is a novel doped metal nanomaterial synthesized by our group using the sonochemical method. Our previous…”
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Transcriptome and proteome analysis reveals the anti-cancer properties of Hypnea musciformis marine macroalga extract in liver and intestinal cancer cells by Begolli, Rodiola, Chatziangelou, Myrto, Samiotaki, Martina, Goutas, Andreas, Barda, Sofia, Goutzourelas, Nikolaos, Kevrekidis, Dimitrios Phaedon, Malea, Paraskevi, Trachana, Varvara, Liu, Ming, Lin, Xiukun, Kollatos, Nikolaos, Stagos, Dimitrios, Giakountis, Antonis

“…Marine seaweeds are considered as a rich source of health-promoting compounds by the food and pharmaceutical industry. Hypnea musciformis is a marine red…”
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Micelle encapsulation zinc‐doped copper oxide nanocomposites reverse Olaparib resistance in ovarian cancer by disrupting homologous recombination repair by Yi, Jingyan, Luo, Xin, Xing, Jinshan, Gedanken, Aharon, Lin, Xiukun, Zhang, Chunxiang, Qiao, Gan

“…Micelle Encapsulation Zinc‐doped copper oxide nanocomposites (MEnZn‐CuO NPs) is a novel doped metal nanomaterial prepared by our group based on Zinc doped…”
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Alkaloids as Anticancer Agents: A Review of Chinese Patents in Recent 5 Years by Tao, Hongyu, Zuo, Ling, Xu, Huanli, Li, Cong, Qiao, Gan, Guo, Mingyue, Lin, Xiukun

“…In recent years, many novel alkaloids with anticancer activity have been found in China, and some of them are promising for developing as anticancer agents…”
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Granulin A Synergizes with Cisplatin to Inhibit the Growth of Human Hepatocellular Carcinoma by Qiao, Gan, Xu, Huanli, Li, Cong, Li, Xiao, Farooqi, Ammad Ahmad, Zhao, Yuming, Liu, Xiaohui, Liu, Ming, Stagos, Dimitrios, Lin, Xiukun

“…Cisplatin is one of the most potent chemotherapy drugs widely used for cancer treatment. However, due to resistance and toxicity, the application of cisplatin…”
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Synthesis and α-glucosidase inhibitory mechanisms of bis(2,3-dibromo-4,5-dihydroxybenzyl) ether, a potential marine bromophenol α-glucosidase inhibitor by Liu, Ming, Zhang, Wei, Wei, Jianteng, Lin, Xiukun

“…Bis(2,3-dibromo-4,5-dihydroxybenzyl) ether (BDDE), derived from the marine algae, is a potential α-glucosidase inhibitor for type 2 diabetes treatment. In the…”
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Synthesis of butyl-isobutyl-phthalate and its interaction with α-glucosidase in vitro by Liu, Ming, Zhang, Wei, Qiu, Lin, Lin, Xiukun

“…Butyl-isobutyl-phthalate (BIP), isolated from the rhizoid of Laminaria japonica, is a potential α-glucosidase inhibitor for Type II diabetes treatment. In the…”
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