Search Results - "Lin, Xin Yao"
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RNA Nanotechnology-Mediated Cancer Immunotherapy
Published in Theranostics (2020)“…RNA molecules (e.g., siRNA, microRNA, and mRNA) have shown tremendous potential for immunomodulation and cancer immunotherapy. They can activate both innate…”
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A self-destructive nanosweeper that captures and clears amyloid β-peptides
Published in Nature communications (04-05-2018)“…Cerebral amyloid β-peptide (Aβ) accumulation resulting from an imbalance between Aβ production and clearance is one of the most important causes in the…”
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A tumour-selective cascade activatable self-detained system for drug delivery and cancer imaging
Published in Nature communications (24-10-2019)“…Achieving the activation of drugs within cellular systems may provide targeted therapies. Here we construct a tumour-selective cascade activatable…”
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Recent Advances in Nanotechnology for Autophagy Detection
Published in Small (Weinheim an der Bergstrasse, Germany) (01-09-2017)“…Autophagy is closely related to various diseases, and is a diagnostic and therapeutic target for some diseases. In recent years, tremendous efforts have been…”
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Transformable Nanomaterials as an Artificial Extracellular Matrix for Inhibiting Tumor Invasion and Metastasis
Published in ACS nano (25-04-2017)“…Tumor metastasis is one of the big challenges in cancer treatment and is often associated with high patient mortality. Until now, there is an agreement that…”
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Engineered CpG‐Loaded Nanorobots Drive Autophagy‐Mediated Immunity for TLR9‐Positive Cancer Therapy
Published in Advanced materials (Weinheim) (01-05-2024)“…Smart nanorobots have emerged as novel drug delivery platforms in nanomedicine, potentially improving anti‐cancer efficacy and reducing side effects. In this…”
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Self-Assembled Autophagy-Inducing Polymeric Nanoparticles for Breast Cancer Interference In-Vivo
Published in Advanced materials (Weinheim) (24-04-2015)“…A peptide‐conjugated poly(β‐amino ester) that self‐assembles into micelle‐like nanoparticles is prepared by a convenient and modular supramolecular approach…”
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A Social Exergame Intervention to Promote Physical Activity, Social Support, and Well-Being in Family Caregivers
Published in The Gerontologist (17-10-2023)“…Abstract Background and Objectives Family caregivers often experience a high level of stress, social isolation, a sedentary lifestyle, and poor mental and…”
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NIR Light Propulsive Janus-like Nanohybrids for Enhanced Photothermal Tumor Therapy
Published in Small (Weinheim an der Bergstrasse, Germany) (01-10-2016)“…Au‐BP7@SP nanohybrids with active motion under NIR laser irradiation can effectively enhance the temperature of tumor potentially by converting the kinetic…”
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The clinical progress and challenges of mRNA vaccines
Published in Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology (01-09-2023)“…Owing to the breakthroughs in the prevention and control of the COVID-19 pandemic, messenger RNA (mRNA)-based vaccines have emerged as promising alternatives…”
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Photothermal Ring Integrated Intraocular Lens for High‐Efficient Eye Disease Treatment
Published in Advanced materials (Weinheim) (01-09-2017)“…Posterior capsule opacification (PCO) is the most common complication after cataract surgery. So far, the only method for PCO treatment is the precisely…”
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An in Situ Intracellular Self-Assembly Strategy for Quantitatively and Temporally Monitoring Autophagy
Published in ACS nano (28-02-2017)“…Autophagy plays a crucial role in the metabolic process. So far, conventional methods are incapable of rapid, precise, and real-time monitoring of autophagy in…”
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A General Strategy for Facile Synthesis and In Situ Screening of Self-Assembled Polymer-Peptide Nanomaterials
Published in Advanced materials (Weinheim) (02-03-2016)“…A universal strategy for efficient, mild, and purification‐free synthesis and in situ screening of functional polymer‐peptide nanomaterials is described. More…”
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pH-Sensitive Polymeric Nanoparticles Modulate Autophagic Effect via Lysosome Impairment
Published in Small (Weinheim an der Bergstrasse, Germany) (01-06-2016)“…In drug delivery systems, pH‐sensitive polymers are commonly used as drug carriers, and significant efforts have been devoted to the aspects of controlled…”
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Reactivation of the tumor suppressor PTEN by mRNA nanoparticles enhances antitumor immunity in preclinical models
Published in Science translational medicine (23-06-2021)“…Increasing clinical evidence has demonstrated that the deletion or mutation of tumor suppressor genes such as the gene-encoding phosphatase and tensin homolog…”
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Unprecedentedly High Tissue Penetration Capability of Co‐Assembled Nanosystems for Two‐Photon Fluorescence Imaging In Vivo
Published in Advanced optical materials (01-05-2015)“…The current challenge in two‐photon fluorescence for biomedical imaging is to develop extremely bright contrast agents with long wavelength emission. A Förster…”
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Peptide-Based Autophagic Gene and Cisplatin Co-delivery Systems Enable Improved Chemotherapy Resistance
Published in Nano letters (08-05-2019)“…Cisplatin-based chemotherapy is a widely used first-line strategy for numerous cancers. However, drug resistances are often inevitable accompanied by the…”
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Polymeric nanoparticles enable reversing macrophage in tumor microenvironment for immunotherapy
Published in Biomaterials (01-01-2017)“…Abstract Immunotherapy has shown a promising effect for a variety of cancers. However, the immune treatment efficiency of solid tumor is limited due to barely…”
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Polymeric nanoparticles promote macrophage reversal from M2 to M1 phenotypes in the tumor microenvironment
Published in Biomaterials (01-01-2017)“…Immunotherapy has shown promising treatment effects for a variety of cancers. However, the immune treatment efficiency for solid tumors is limited owing to…”
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A Bidirectional Fiber-Wireless and Fiber-IVLLC Convergence System with a Dual-Polarization Modulation Scheme and an MZM-OEO-Based BLS
Published in IEEE photonics journal (01-10-2016)“…A bidirectional fiber-wireless and fiber-invisible laser light communication (IVLLC) convergence system that adopts a dual-polarization modulation scheme and a…”
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