Search Results - "Lin, Wee"

Biodegradable Broad-Spectrum Antimicrobial Polycarbonates: Investigating the Role of Chemical Structure on Activity and Selectivity by Chin, Willy, Yang, Chuan, Ng, Victor Wee Lin, Huang, Yuan, Cheng, Junchi, Tong, Yen Wah, Coady, Daniel J, Fan, Weimin, Hedrick, James L, Yang, Yi Yan

“…A series of biodegradable polycarbonate polymers was designed and synthesized via organocatalytic ring-opening polymerization of functional cyclic carbonate…”
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Antimicrobial Polycarbonates: Investigating the Impact of Nitrogen-Containing Heterocycles as Quaternizing Agents by Ng, Victor Wee Lin, Tan, Jeremy Pang Kern, Leong, Jiayu, Voo, Zhi Xiang, Hedrick, James L, Yang, Yi Yan

“…Synthetic polymeric antimicrobials have received enormous attention recently on the back of increasing multidrug-resistance microbes. While conventional small…”
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Co-delivery of thioridazine and doxorubicin using polymeric micelles for targeting both cancer cells and cancer stem cells by Ke, Xi-Yu, Lin Ng, Victor Wee, Gao, Shu-Jun, Tong, Yen Wah, Hedrick, James L, Yang, Yi Yan

“…Abstract In this study, thioridazine (THZ), which was reported to kill cancer stem cells, was used in a combination therapy with doxorubicin (DOX) to eradicate…”
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Beyond digital interfaces: The human element in online teaching and its influence on student experiences by Chai, Soo See, Ting, Su-Hie, Goh, Kok Luong, Chang, Yee Hui Robin, Wee, Bui Lin, Novita, Dila, Karthikeyan, J

“…Amidst the digital transformation of education, the essence of the human touch in online teaching remains pivotal. Despite growing literature, there remains a…”
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Patient-Reported Outcome Measures in Registry-Based Studies of Type 2 Diabetes Mellitus: a Systematic Review by Chen, Yu Ting, Tan, Yan Zhi, Cheen, Mcvin, Wee, Hwee-Lin

“…Purpose of Review Patient-reported outcome measures (PROMs) and patient registries both play important roles in assessing patient outcomes. However, no study…”
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Cancer screening programs in South-east Asia and Western Pacific by Wee, Hwee-Lin, Canfell, Karen, Chiu, Han-Mo, Choi, Kui Son, Cox, Brian, Bhoo-Pathy, Nirmala, Simms, Kate T, Hamashima, Chisato, Shen, Qianyu, Chua, Brandon, Siwaporn, Niyomsri, Toes-Zoutendijk, Esther

“…The burden of cancer can be altered by screening. The field of cancer screening is constantly evolving; from the initiation of program for new cancer types as…”
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Synergistic Co-Delivery of Membrane-Disrupting Polymers with Commercial Antibiotics against Highly Opportunistic Bacteria by Ng, Victor Wee Lin, Ke, Xiyu, Lee, Ashlynn L. Z., Hedrick, James L., Yang, Yi Yan

“…A series of vitamin E‐containing biodegradable antimicrobial cationic polycarbonates is designed and synthesized via controlled organocatalytic ring‐opening…”
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Performance of Single-Nucleotide Polymorphisms in Breast Cancer Risk Prediction Models: A Systematic Review and Meta-analysis by Fung, Si Ming, Wong, Xin Yi, Lee, Shi Xun, Miao, Hui, Hartman, Mikael, Wee, Hwee-Lin

“…SNP risk information can potentially improve the accuracy of breast cancer risk prediction. We aim to review and assess the performance of SNP-enhanced risk…”
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Synthesis of the Ca2+-mobilizing messengers NAADP and cADPR by intracellular CD38 enzyme in the mouse heart: Role in β-adrenoceptor signaling by Lin, Wee K., Bolton, Emma L., Cortopassi, Wilian A., Wang, Yanwen, O'Brien, Fiona, Maciejewska, Matylda, Jacobson, Matthew P., Garnham, Clive, Ruas, Margarida, Parrington, John, Lei, Ming, Sitsapesan, Rebecca, Galione, Antony, Terrar, Derek A.

“…Nicotinic acid adenine dinucleotide phosphate (NAADP) and cyclic ADP-ribose (cADPR) are Ca2+-mobilizing messengers important for modulating cardiac…”
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Inhibition of angiotensin II-induced cardiac hypertrophy and associated ventricular arrhythmias by a p21 activated kinase 1 bioactive peptide by Wang, Rui, Wang, Yanwen, Lin, Wee K, Zhang, Yanmin, Liu, Wei, Huang, Kai, Terrar, Derek A, Solaro, R John, Wang, Xin, Ke, Yunbo, Lei, Ming

“…Cardiac hypertrophy increases the risk of morbidity and mortality of cardiovascular disease and thus inhibiting such hypertrophy is beneficial. In the present…”
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Determinants of Health-Related Quality of Life (HRQoL) in the Multiethnic Singapore Population - A National Cohort Study by Leow, Melvin Khee-Shing, Griva, Konstadina, Choo, Robin, Wee, Hwee-Lin, Thumboo, Julian, Tai, E Shyong, Newman, Stanton

“…HRQoL is an important outcome to guide and promote healthcare. Clinical and socioeconomic factors may influence HRQoL according to ethnicity. A multiethnic…”
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Economic burden of adverse drug reactions and potential for pharmacogenomic testing in Singaporean adults by Chan, Sze Ling, Ng, Hong Yen, Sung, Cynthia, Chan, Alexandre, Winther, Michael D, Brunham, Liam R, Wee, Hwee-Lin

“…Adverse drug reactions (ADRs) contribute to hospitalization but data on its economic burden is scant. Pre-emptive pharmacogenetic (PGx) testing can potentially…”
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Two-pore Channels (TPC2s) and Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) at Lysosomal-Sarcoplasmic Reticular Junctions Contribute to Acute and Chronic β-Adrenoceptor Signaling in the Heart by Capel, Rebecca A., Bolton, Emma L., Lin, Wee K., Aston, Daniel, Wang, Yanwen, Liu, Wei, Wang, Xin, Burton, Rebecca-Ann B., Bloor-Young, Duncan, Shade, Kai-Ting, Ruas, Margarida, Parrington, John, Churchill, Grant C., Lei, Ming, Galione, Antony, Terrar, Derek A.

“…Ca2+-permeable type 2 two-pore channels (TPC2) are lysosomal proteins required for nicotinic acid adenine dinucleotide phosphate (NAADP)-evoked Ca2+ release in…”
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Does health‐related quality of life in Asian informal caregivers differ between early‐onset dementia and late‐onset dementia? by Wang, Vivian W., Kandiah, Nagaendran, Lin, Xuling, Wee, Hwee‐Lin

“…Aim Early‐onset dementia (EOD) (defined as dementia onset before age 65) presents specific challenges and issues, adding to the negative impact of dementia on…”
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Association of anemia and mineral and bone disorder with health-related quality of life in Asian pre-dialysis patients by Wee, Hwee-Lin, Seng, Benjamin Jun Jie, Lee, Jia Jia, Chong, Kok Joon, Tyagi, Pallavi, Vathsala, Anantharaman, How, Priscilla

“…Patients with chronic kidney disease (CKD) have poor health-related quality of life (HRQoL). The association of CKD-related complications such as anemia and…”
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Associations of lifestyle factors, disease history and awareness with health-related quality of life in a Thai population by Vathesatogkit, Prin, Sritara, Piyamitr, Kimman, Merel, Hengprasith, Bunlue, E-Shyong, Tai, Wee, Hwee-Lin, Woodward, Mark

“…The impact of the presence and awareness of individual health states on quality of life (HRQoL) is often documented. However, the impacts of different health…”
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Barriers to and Facilitators of Cervical Cancer Screening among Women in Southeast Asia: A Systematic Review by Chua, Brandon, Ma, Viva, Asjes, Caitlin, Lim, Ashley, Mohseni, Mahsa, Wee, Hwee Lin

“…In Southeast Asia, cervical cancer is the second most common cancer in women. Low coverage for cervical cancer screening (CCS) becomes a roadblock to disease…”
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Economic Analysis of Border Control Policies during COVID-19 Pandemic: A Modelling Study to Inform Cross-Border Travel Policy between Singapore and Thailand by Cai, Celestine Grace Xueting, Lim, Nigel Wei-Han, Huynh, Vinh Anh, Ananthakrishnan, Aparna, Dabak, Saudamini Vishwanath, Dickens, Borame Sue Lee, Faradiba, Dian, Kc, Sarin, Morton, Alec, Park, Minah, Rachatan, Chayapat, Sittimart, Manit, Wee, Hwee-Lin, Lou, Jing, Teerawattananon, Yot

“…With countries progressing towards high COVID-19 vaccination rates, strategies for border reopening are required. This study focuses on Thailand and Singapore,…”
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The impact of axial spondyloarthritis on quality of life (QoL): a comparison with the impact of moderate to end-stage chronic kidney disease on QoL by Kwan, Yu Heng, Fong, Warren, How, Priscilla, Wee, Hwee-Lin, Leung, Ying Ying, Phang, Jie Kie, Lui, Nai Lee, Tan, Chuen Seng, Malhotra, Rahul, Østbye, Truls, Thumboo, Julian

“…Purpose The purpose of the study was to assess the impact of axial spondyloarthritis (axSpA) on patients' quality of life (QoL) compared to patients with…”
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The Relative Importance of Vulnerability and Efficiency in COVID-19 Contact Tracing Programmes: A Discrete Choice Experiment by Wang, Yi, Faradiba, Dian, Del Rio Vilas, Victor J., Asaria, Miqdad, Chen, Yu Ting, Babigumira, Joseph Brian, Dabak, Saudamini Vishwanath, Wee, Hwee-Lin

“…Objectives: This study aims to assess the trade-offs between vulnerability and efficiency attributes of contact tracing programmes based on preferences of…”
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