Search Results - "Lin, Sonyuan"

Endocannabinoid enhancement protects against kainic acid-induced seizures and associated brain damage by Karanian, David A, Karim, Sanjida L, Wood, JodiAnne T, Williams, John S, Lin, Sonyuan, Makriyannis, Alexandros, Bahr, Ben A

“…Endocannabinoids are released in response to pathogenic insults, and inhibitors of endocannabinoid inactivation enhance such on-demand responses that promote…”
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Structure−Activity Relationships of Pyrazole Derivatives as Cannabinoid Receptor Antagonists by Lan, Ruoxi, Liu, Qian, Fan, Pusheng, Lin, Sonyuan, Fernando, Susanthi R, McCallion, Deirdre, Pertwee, Roger, Makriyannis, Alexandros

“…As a potent, specific antagonist for the brain cannabinoid receptor (CB1), the biarylpyrazole…”
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Novel Analogues of Arachidonylethanolamide (Anandamide):  Affinities for the CB1 and CB2 Cannabinoid Receptors and Metabolic Stability by Lin, Sonyuan, Khanolkar, Atmaram D, Fan, Pusheng, Goutopoulos, Andreas, Qin, Ce, Papahadjis, Demetris, Makriyannis, Alexandros

“…Several analogues of the endogenous cannabinoid receptor ligand arachidonylethanolamide (anandamide) were synthesized and evaluated in order to study (a) the…”
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(R)-Methanandamide: A Chiral Novel Anandamide Possessing Higher Potency and Metabolic Stability by Abadji, Vasiliki, Lin, Sonyuan, Taha, Gihan, Griffin, Graeme, Stevenson, Lesley A, Pertwee, Roger G, Makriyannis, Alexandros

“…Four chiral congeners of arachidonylethanolamide (anandamide) have been synthesized and evaluated for (a) their ability to bind to the cannabinoid receptor in…”
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Substrate Specificity and Stereoselectivity of Rat Brain Microsomal Anandamide Amidohydrolase by Lang, Wensheng, Qin, Ce, Lin, Sonyuan, Khanolkar, Atmaram D, Goutopoulos, Andreas, Fan, Pusheng, Abouzid, Khaled, Meng, Zhaoxing, Biegel, Diane, Makriyannis, Alexandros

“…Anandamide amidohydrolase (AAH) catalyzes the hydrolysis of arachidonylethanolamide (anandamide), an endogenous cannabinoid receptor ligand. To delineate the…”
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Stereochemical Selectivity of Methanandamides for the CB1 and CB2 Cannabinoid Receptors and Their Metabolic Stability by Goutopoulos, Andreas, Fan, Pusheng, Khanolkar, Atmaram D, Xie, Xian-Qun, Lin, Sonyuan, Makriyannis, Alexandros

“…Several chiral, analogues of the endogenous cannabinoid receptor ligand, arachidonylethanolamide (anandamide), methylated at the 2,1′ and 2′ positions using…”
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Head Group Analogs of Arachidonylethanolamide, the Endogenous Cannabinoid Ligand by Khanolkar, Atmaram D, Abadji, Vasiliki, Lin, Sonyuan, Hill, W. Adam G, Taha, Gihan, Abouzid, Khaled, Meng, Zhaoxing, Fan, Pusheng, Makriyannis, Alexandros

“…Several analogs of an endogenous cannabimimetic, arachidonylethanolamide (anandamide), were synthesized to study the structural requirements of the…”
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Potentiation of the action of anandamide on hippocampal slices by the fatty acid amide hydrolase inhibitor, palmitylsulphonyl fluoride (AM 374) by Gifford, Andrew N, Bruneus, Magalie, Lin, Sonyuan, Goutopoulos, Andreas, Makriyannis, Alexandros, Volkow, Nora D, Gatley, S.John

“…The electrically-evoked release of [ 3H]acetylcholine from hippocampal brain slices is inhibited by cannabinoid receptor agonists. The effect of…”
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The role of halogen substitution in classical cannabinoids: a CB1 pharmacophore model by Nikas, Spyros P, Grzybowska, Jolanta, Papahatjis, Demetris P, Charalambous, Avgui, Banijamali, Ali R, Chari, Ravi, Fan, Pusheng, Kourouli, Therapia, Lin, Sonyuan, Nitowski, Albert J, Marciniak, Gilbert, Guo, Yan, Li, Xiuyan, Wang, Chia-Lin J, Makriyannis, Alexandros

“…The presence of halogens within the classical cannabinoid structure leads to large variations in the compounds' potencies and affinities for the CB1 receptors…”
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Determination of Anandamide Amidase Activity Using Ultraviolet-Active Amine Derivatives and Reverse-Phase High-Performance Liquid Chromatography by Qin, Ce, Lin, Sonyuan, Lang, Wensheng, Goutopoulos, Andreas, Pavlopoulos, Spiro, Mauri, Frank, Makriyannis, Alexandros

“…Anandamide amidase catalyzes the hydrolysis of anandamide (AEA) to arachidonic acid (AA) and ethanolamine (EA). Recently, we published a method for determining…”
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High-Performance Liquid Chromatographic Determination of Anandamide Amidase Activity in Rat Brain Microsomes by Lang, Wensheng, Qin, Ce, Hill, W.Adam G., Lin, Sonyuan, Khanolkar, Atmaram D., Makriyannis, Alexandros

“…A rapid, sensitive, and reliable method for measuring anandamide amidase activity in rat brain microsomes by reversed-phase high-performance liquid…”
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Preparation of optically pure 4-(hydroxymethyl)-2-pentadecyl-1,3-dioxolanes and their corresponding phosphodiester ether lipid derivatives by Lin, Sonyuan, Duclos, Richard I, Makriyannis, Alexandros

“…Semi-preparative HPLC on a chiral stationary phase (Chiracel OD) was utilized in the course of this synthesis to separate the four possible diastereomers […”
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High-Performance Liquid Chromatographic Determination of Anandamide Amidase Activity in Rat Brain Microsomes: Volume238,Number 1 (1996), pages 40–45 by Lang, Wensheng, Qin, Ce, Hill, W.Adam G., Lin, Sonyuan, Khanolkar, Atmaram D., Makriyannis, Alexandros

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Substrate Specificity and Stereoselectivity of Rat Brain Microsomal Anandamide Amidohydrolase by Lang, Wensheng, Qin, Ce, Lin, Sonyuan, Khanolkar, Atmaram D, Goutopoulos, Andreas, Fan, Pusheng, Abouzid, Khaled, Meng, Zhaoxing, Biegel, Diane, Makriyannis, Alexandros

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Interdigitation of bilayers from ether lipid analogs: ( R)-PAF, ( R)-Lyso-PAF and the antineoplastic ( R)-ET-18-OMe by Xie, Xiangqun, Lin, Sonyuan, Moring, Jill, Makriyannis, Alexandros

“…The ether lipid analogs ( R)-PAF, ( R)-ET-18-OMe and ( R)-Lyso-PAF can form bilayers. Using differential scanning calorimetry (DSC) and small angle X-ray…”
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Syntheses of 1,2-di- O-palmitoyl- sn-glycero-3-phosphocholine (DPPC) and analogs with 13C- and 2H-labeled choline head groups by Lin, Sonyuan, Duclos, Richard I, Makriyannis, Alexandros

“…The syntheses of four head group labeled analogs of 1,2-di- O-palmitoyl- sn-glycero-3-phosphocholine (DPPC) ( 6) by a general method from 1,2-di- O-palmitoyl-…”
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High-Performance Liquid Chromatographic Determination of Anandamide Amidase Activity in Rat Brain Microsomes by Lang, Wensheng, Qin, Ce, Hill, W.Adam G., Lin, Sonyuan, Khanolkar, Atmaram D., Makriyannis, Alexandros

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