Search Results - "Lin, Shuye"
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Downregulation of miR-142-5p promotes tumor metastasis through directly regulating CYR61 expression in gastric cancer
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01-03-2019)“…Background Recurrence is a primary cause of gastric cancer (GC)-related deaths. We reported previously that low expression of miR-142-5p could predict…”
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Whole-genome sequencing reveals novel tandem-duplication hotspots and a prognostic mutational signature in gastric cancer
Published in Nature communications (02-05-2019)“…Genome-wide analysis of genomic signatures might reveal novel mechanisms for gastric cancer (GC) tumorigenesis. Here, we analysis structural variations (SVs)…”
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FAM3D is essential for colon homeostasis and host defense against inflammation associated carcinogenesis
Published in Nature communications (20-11-2020)“…The physiological homeostasis of gut mucosal barrier is maintained by both genetic and environmental factors and its impairment leads to pathogenesis such as…”
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4
Deep learning survival model for colorectal cancer patients (DeepCRC) with Asian clinical data compared with different theories
Published in Archives of medical science (01-01-2023)“…Colorectal cancer (CRC) is the third most common cancer. Precise prediction of CRC patients' overall survival (OS) probability could offer advice on its…”
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Tumor suppressor ATP4B serve as a promising biomarker for worsening of gastric atrophy and poor differentiation
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01-03-2021)“…Background Hydrogen/potassium ATPase β (ATP4B) is a proton pump acting an essential role in gastric acid secretion. This study aimed to investigate the…”
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Prognostic analysis of destroyed-lung patients with preoperative massive hemoptysis: a 20-year retrospective study
Published in BMC pulmonary medicine (21-08-2024)“…Surgery is the main treatment option for destroyed-lung (DL) patients with life-threatening massive hemoptysis. However, short-term and long-term surgical…”
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Lysine succinylation, the metabolic bridge between cancer and immunity
Published in Genes & diseases (01-11-2023)“…Lysine succinylation is a naturally occurring post-translational modification (PTM) that regulates the stability and function of proteins. It can be regulated…”
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Epigenetic downregulation of MUC17 by H. pylori infection facilitates NF-κB-mediated expression of CEACAM1-3S in human gastric cancer
Published in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (01-09-2019)“…Background and aims Helicobacter pylori invades the mucosal barrier and infects the mucins of gastric epithelial cells. However, whether gastric carcinogenesis…”
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UHRF1/DNMT1–MZF1 axis-modulated intragenic site-specific CpGI methylation confers divergent expression and opposing functions of PRSS3 isoforms in lung cancer
Published in Acta pharmaceutica Sinica. B (01-05-2023)“…As confusion mounts over RNA isoforms involved in phenotypic plasticity, aberrant CpG methylation-mediated disruption of alternative splicing is increasingly…”
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CpG Site-Specific Methylation-Modulated Divergent Expression of PRSS3 Transcript Variants Facilitates Nongenetic Intratumor Heterogeneity in Human Hepatocellular Carcinoma
Published in Frontiers in oncology (11-04-2022)“…Hepatocellular carcinoma (HCC) is one of the most lethal human tumors with extensive intratumor heterogeneity (ITH). Serine protease 3 (PRSS3) is an…”
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Garlic‐derived compounds: Epigenetic modulators and their antitumor effects
Published in Phytotherapy research (01-03-2024)“…Cancer is a highly heterogeneous disease that poses a serious threat to human health worldwide. Despite significant advances in the diagnosis and treatment of…”
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Batch-fed composting of food waste: Microbial diversity characterization and removal of antibiotic resistance genes
Published in Bioresource technology (01-10-2023)“…[Display omitted] •BFC has the advantage of maintaining a high temperature for an extended period.•BFC was beneficial for increasing bacterial diversity and…”
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Key Factors Associated With Administration of Ventilator Support After Thymoma Resection
Published in The Journal of surgical research (01-09-2022)“…In clinical practice, some patients undergoing surgery for thymoma require post-surgical ventilator support, although, factors associated with administration…”
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Acquired resistance to EGFR-TKIs in NSCLC mediates epigenetic downregulation of MUC17 by facilitating NF-κB activity via UHRF1/DNMT1 complex
Published in International journal of biological sciences (2023)“…Treatment with epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) has brought significant benefits to non-small cell lung cancer (NSCLC)…”
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15
Human umbilical cord mesenchymal stem cells alleviated TNBS-induced colitis in mice by restoring the balance of intestinal microbes and immunoregulation
Published in Life sciences (1973) (01-12-2023)“…Human umbilical cord mesenchymal stem cells (HUMSCs) have been documented to be effective for several immune disorders including inflammatory bowel diseases…”
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Epigenetic Upregulation of Metallothionein 2A by Diallyl Trisulfide Enhances Chemosensitivity of Human Gastric Cancer Cells to Docetaxel Through Attenuating NF-κB Activation
Published in Antioxidants & redox signaling (20-05-2016)“…Metallothionein 2A (MT2A) and nuclear factor-kappaB (NF-κB) are both involved in carcinogenesis and cancer chemosensitivity. We previously showed decreased…”
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Transcription Factor Myeloid Zinc-Finger 1 Suppresses Human Gastric Carcinogenesis by Interacting with Metallothionein 2A
Published in Clinical cancer research (01-02-2019)“…Metallothionein 2A (MT2A) suppresses the progression of human gastric cancer potentially through an "MT2A-NF-κB pathway" with unclear mechanisms. This study…”
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New genetic and epigenetic insights into the chemokine system: the latest discoveries aiding progression toward precision medicine
Published in Cellular & molecular immunology (01-07-2023)“…Over the past thirty years, the importance of chemokines and their seven-transmembrane G protein-coupled receptors (GPCRs) has been increasingly recognized…”
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Differential MUC22 expression by epigenetic alterations in human lung squamous cell carcinoma and adenocarcinoma
Published in Oncology reports (01-05-2021)“…Disruption in mucins (MUCs) is involved in cancer development and metastasis and is thus used as a biomarker. Non‑small cell lung carcinoma (NSCLC) is…”
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Identification of key genes in HER2-positive breast cancer with brain metastasis via bioinformatics methods
Published in Translational cancer research (31-05-2023)“…Brain metastasis (BM) represents one of the most common advanced disease states in breast cancer (BC), especially in human epidermal growth factor receptor 2…”
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