Search Results - "Lin, Philana L."

Defining a core breath profile for healthy, non-human primates by Bobak, Carly A., Stevenson, Keisean A. J. M., Sun, Ning, Khan, Mohammad S., Azmir, Jannatul, Beccaria, Marco, Tomko, Jaime A., Fillmore, Daniel, Scanga, Charles A., Lin, Philana L., Flynn, JoAnne L., Hill, Jane E.

“…Non-human primates remain the most useful and reliable pre-clinical model for many human diseases. Primate breath profiles have previously distinguished…”
Get full text

Serotype 19A Is the Most Common Serotype Causing Invasive Pneumococcal Infections in Children by KAPLAN, Sheldon L, BARSON, William J, LIN, Philana L, STOVALL, Stephanie H, BRADLEY, John S, TAN, Tina Q, HOFFMAN, Jill A, GIVNER, Laurence B, MASON, Edward O

“…The purpose of this study was to monitor the clinical and microbiologic features of invasive infections caused by Streptococcus pneumoniae among children…”
Get full text

Experimental Mycobacterium tuberculosis Infection of Cynomolgus Macaques Closely Resembles the Various Manifestations of Human M. tuberculosis Infection by CAPUANO, Saverio V, CROIX, Denise A, PAWAR, Santosh, ZINOVIK, Angelica, MYERS, Amy, LIN, Philana L, BISSEL, Stephanie, FUHRMAN, Carl, KLEIN, Edwin, FLYNN, Joanne L

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Activated B Cells in the Granulomas of Nonhuman Primates Infected with Mycobacterium tuberculosis by Phuah, Jia Yao, Mattila, Joshua T, Lin, Philana L, Flynn, JoAnne L

“…In an attempt to contain Mycobacterium tuberculosis , host immune cells form a granuloma as a physical and immunological barrier. To date, the contribution of…”
Get full text

Visualizing the dynamics of tuberculosis pathology using molecular imaging by Ordonez, Alvaro A, Tucker, Elizabeth W, Anderson, Carolyn J, Carter, Claire L, Ganatra, Shashank, Kaushal, Deepak, Kramnik, Igor, Lin, Philana L, Madigan, Cressida A, Mendez, Susana, Rao, Jianghong, Savic, Rada M, Tobin, David M, Walzl, Gerhard, Wilkinson, Robert J, Lacourciere, Karen A, Via, Laura E, Jain, Sanjay K

“…Nearly 140 years after Robert Koch discovered Mycobacterium tuberculosis, tuberculosis (TB) remains a global threat and a deadly human pathogen. M…”
Get full text

A new method to evaluate macaque health using exhaled breath: A case study of M. tuberculosis in a BSL-3 setting by Mellors, Theodore R, Blanchet, Lionel, Flynn, JoAnne L, Tomko, Jaime, O'Malley, Melanie, Scanga, Charles A, Lin, Philana L, Hill, Jane E

“…Breath is hypothesized to contain clinically relevant information, useful for the diagnosis and monitoring of disease, as well as understanding underlying…”
Get full text

Actinomycotic Mastoiditis Complicated by Sigmoid Sinus Thrombosis and Labyrinthine Fistula by Lezcano, Cecilia, Simons, Jeffrey P., Colman, Kathryn L., Cohen, Michael S., Lin, Philana L., Reyes-Múgica, Miguel

“…Actinomyces is a rare pathogen that can be the cause of infections in the digestive and urinary tracts, skin, genitalia, and lungs, which generally have an…”
Get full text

Altered Neutrophil Counts at Diagnosis of Invasive Meningococcal Infection in Children by DEMISSIE, Dawit E, KAPLAN, Sheldon L, LIN, Philana L, EDWARDS, Kathryn M, MASON, Edward O, COOPERSTOCK, Michael S, ROMERO, Jose R, LEAKE, John A. D, BARSON, William J, HALASA, Natasha B, BYINGTON, Carrie L, SHETTY, Avinash K, TAN, Tina Q, HOFFMAN, Jill A

“…Invasive meningococcal infections can be devastating. Substantial endotoxemia releases mature and immature neutrophils. Endothelial margination of mature…”
Get full text

In vivo imaging in an ABSL-3 regional biocontainment laboratory by Scanga, Charles A., Lopresti, Brian J., Tomko, Jaime, Frye, Lonnie J., Coleman, Teresa M., Fillmore, Daniel, Carney, Jonathan P., Lin, Philana L., Flynn, JoAnne L., Gardner, Christina L., Sun, Chengqun, Klimstra, William B., Ryman, Kate D., Reed, Douglas S., Fisher, Daniel J., Cole, Kelly S.

“…Abstract The Regional Biocontainment Laboratory (RBL) at the University of Pittsburgh is a state of the art ABSL 3 facility that supports research on highly…”
Get full text

Variability in tuberculosis granuloma T cell responses exists, but a balance of pro- and anti-inflammatory cytokines is associated with sterilization by Gideon, Hannah Priyadarshini, Phuah, JiaYao, Myers, Amy J, Bryson, Bryan D, Rodgers, Mark A, Coleman, M Teresa, Maiello, Pauline, Rutledge, Tara, Marino, Simeone, Fortune, Sarah M, Kirschner, Denise E, Lin, Philana Ling, Flynn, JoAnne L

“…Lung granulomas are the pathologic hallmark of tuberculosis (TB). T cells are a major cellular component of TB lung granulomas and are known to play an…”
Get full text

Vaccine-Elicited T cells are Important for Intravenous BCG Mediated Protection in a Rhesus macaque Model of Tuberculosis by Zeppa, Joseph John, Darrah, Patricia A, Sutton, Matthew, Pokkali, Supriya, Scanga, Chuck A, Maiello, Pauline, Lin, Philana L, Roederer, Mario, Seder, Robert A, Flynn, JoAnne L

“…Our laboratories have shown that intravenous (IV) vaccination with Bacille Calmette-Guerin (BCG; 5×107 CFU) provides robust protection against low-dose…”
Get full text

176. Selected Impact of the 13-valent Pneumococcal Conjugate Vaccine (PCV13) on Invasive Pneumococcal Disease (IPD) at Eight Children’s Hospitals in the United States. 2014–2019 by Kaplan, Sheldon L, Barson, William J, Lin, Philana L, Romero, Jose R, Bradley, John S, Tan, Tina Q, Pannaraj, Pia S, Givner, Larry, Hulten, Kristina G

Get full text

183. Decrease in Invasive Pneumococcal Disease in 7 United States Children’s Hospitals during the COVID-19 Pandemic by Clemente, Adriana Sarmiento, Kaplan, Sheldon L, Barson, William J, Lin, Philana L, Romero, Jose R, Bradley, John S, Tan, Tina Q, Pannaraj, Pia S, Givner, Larry, Hulten, Kristina G

Get full text

Actinomycosis Mastoiditis Complicated by Sigmoid Sinus Thrombosis and Labyrinthine Fistula by Colman, Kathryn L., Cohen, Michael S., Reyes-Mugica, Miguel, Lin, Philana L., Simons, Jeffrey P.

Get full text

Incidence of Invasive Pneumococcal Disease in Children 3 to 36 Months of Age at a Tertiary Care Pediatric Center 2 Years After Licensure of the Pneumococcal Conjugate Vaccine by Lin, Philana Ling, Michaels, Marian G, Janosky, Janine, Ortenzo, Michelene, Wald, Ellen R, Mason, Edward O., Jr

“…A dramatic decline in the incidence of invasive disease caused by Streptococcus pneumoniae among healthy infants is anticipated to result from universal…”
Get full text