Search Results - "Lin, Paul"
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The Potential Use of Plant Natural Products and Plant Extracts with Antioxidant Properties for the Prevention/Treatment of Neurodegenerative Diseases: In Vitro, In Vivo and Clinical Trials
Published in Molecules (Basel, Switzerland) (11-12-2018)“…Neurodegenerative disorders, including Alzheimer's disease, Parkinson's disease and Huntington's disease, present a major health issue and financial burden for…”
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In vitro fertilization is safe for women undergoing the treatment after they deliver: a call to arms for the children, too
Published in Fertility and sterility (01-03-2020)Get full text
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Synthesis and Evaluation of Polymer-Drug Conjugates as Potential Antioxidants and Cholinesterase Inhibitors for Neurodegenerative Diseases
Published in Chemistry of materials (12-11-2024)“…Polymer-drug conjugates (PDCs) may offer improved water-solubility and in vitro activity of potential antioxidant and cholinesterase (ChE) inhibitor drugs…”
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New Persistent Opioid Use After Minor and Major Surgical Procedures in US Adults
Published in JAMA surgery (01-06-2017)“…Despite increased focus on reducing opioid prescribing for long-term pain, little is known regarding the incidence and risk factors for persistent opioid use…”
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Short term use of oral corticosteroids and related harms among adults in the United States: population based cohort study
Published in BMJ (Online) (12-04-2017)“…Objective To determine the frequency of prescriptions for short term use of oral corticosteroids, and adverse events (sepsis, venous thromboembolism,…”
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Radiation safety program for the cardiac catheterization laboratory
Published in Catheterization and cardiovascular interventions (01-03-2011)“…The Society of Cardiovascular Angiography and Interventions present a practical approach to assist cardiac catheterization laboratories in establishing a…”
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Pexidartinib versus placebo for advanced tenosynovial giant cell tumour (ENLIVEN): a randomised phase 3 trial
Published in The Lancet (British edition) (10-08-2019)“…Tenosynovial giant cell tumour (TGCT), a rare, locally aggressive neoplasm, overexpresses colony-stimulating factor 1 (CSF1). Surgery is standard with no…”
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Synthesis and in vitro evaluation of vanillin derivatives as multi-target therapeutics for the treatment of Alzheimer’s disease
Published in Bioorganic & medicinal chemistry letters (01-11-2020)“…[Display omitted] •A series of naphthalimido and phthalimido vanillin derivatives were designed and synthesised using a multi-target hybrid-based…”
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IL-6 expression regulates tumorigenicity and correlates with prognosis in bladder cancer
Published in PloS one (30-04-2013)“…Identification of potential tumor markers will help stratify and identify a tumor's malignant potential and its response to specific therapies. IL-6 has been…”
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The synergistic effect between graphene oxide nanocolloids and silicon dioxide nanoparticles for gallic acid sensing
Published in Journal of solid state electrochemistry (19-06-2019)“…For the first time, the synergistic effect of graphene oxide nanocolloids (nano-GO) and silicon dioxide (silica) nanoparticles (SiO 2 -nanoparicles) has been…”
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Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF -mutant melanoma
Published in Nature (London) (30-09-2010)“…B-RAF is the most frequently mutated protein kinase in human cancers. The finding that oncogenic mutations in BRAF are common in melanoma, followed by the…”
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Novel vanillin derivatives: Synthesis, anti-oxidant, DNA and cellular protection properties
Published in European journal of medicinal chemistry (01-01-2018)“…Antioxidants have been the subject of intense research interest mainly due to their beneficial properties associated with human health and wellbeing. Phenolic…”
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Determination of sinapine in rapeseed pomace extract: Its antioxidant and acetylcholinesterase inhibition properties
Published in Food chemistry (15-03-2019)“…•Quantitative determination of bioactive sinapine in rapeseed pomace (RSP) extract.•Anti-oxidant/radical scavenging properties of sinapine at RSP extract…”
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RAF inhibitors that evade paradoxical MAPK pathway activation
Published in Nature (London) (22-10-2015)“…Next-generation RAF inhibitors that inhibit oncogenic BRAF without inducing paradoxical pathway activation in cells with mutant RAS might yield improved safety…”
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Construction and evolution of an Escherichia coli strain relying on nonoxidative glycolysis for sugar catabolism
Published in Proceedings of the National Academy of Sciences - PNAS (03-04-2018)“…The Embden–Meyerhoff–Parnas (EMP) pathway, commonly known as glycolysis, represents the fundamental biochemical infrastructure for sugar catabolism in almost…”
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Traumatic Spinal Cord Injury and Risk of Early and Late Onset Alzheimer’s Disease and Related Dementia: Large Longitudinal Study
Published in Archives of physical medicine and rehabilitation (01-06-2021)“…Traumatic spinal cord injury (TSCI) is a life altering event most often causing permanent physical disability. Little is known about the risk of developing…”
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Consolidated bioprocessing of cellulose to isobutanol using Clostridium thermocellum
Published in Metabolic engineering (01-09-2015)“…Consolidated bioprocessing (CBP) has the potential to reduce biofuel or biochemical production costs by processing cellulose hydrolysis and fermentation…”
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MSCs: Delivery Routes and Engraftment, Cell-Targeting Strategies, and Immune Modulation
Published in Stem Cells International (01-01-2013)“…Mesenchymal stem cells (MSCs) are currently being widely investigated both in the lab and in clinical trials for multiple disease states. The differentiation,…”
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The role of PD-L1 in the radiation response and prognosis for esophageal squamous cell carcinoma related to IL-6 and T-cell immunosuppression
Published in Oncotarget (16-02-2016)“…The aim of this study was to assess the significance of programmed cell death 1 ligand 1 (PD-L1) in esophageal squamous cell carcinoma (ESCC) and its…”
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