Search Results - "Lin, Nina H"

Intragenic proviral elements support transcription of defective HIV-1 proviruses by Kuniholm, Jeffrey, Armstrong, Elise, Bernabe, Brandy, Coote, Carolyn, Berenson, Anna, Patalano, Samantha D, Olson, Alex, He, Xianbao, Lin, Nina H, Fuxman Bass, Juan I, Henderson, Andrew J

“…HIV-1 establishes a persistent proviral reservoir by integrating into the genome of infected host cells. Current antiretroviral treatments do not target this…”
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Early administration of interleukin-6 inhibitors for patients with severe COVID-19 disease is associated with decreased intubation, reduced mortality, and increased discharge by Sinha, Pranay, Mostaghim, Anahita, Bielick, Catherine G., McLaughlin, Angela, Hamer, Davidson H., Wetzler, Lee M., Bhadelia, Nahid, Fagan, Maura A., Linas, Benjamin P., Assoumou, Sabrina A., Ieong, Michael H., Lin, Nina H., Cooper, Ellen R., Brade, Karrine D., White, Laura F., Barlam, Tamar F., Sagar, Manish

“…•Observational data on interleukin-6 receptor inhibitors (IL6ri) for COVID-19 disease are reported.•IL6ri therapy was found to be associated with improved…”
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Coronary Microcirculatory Dysfunction in People With HIV and Its Association With Antiretroviral Therapy by Huck, Daniel M, Weber, Brittany, Parks, Sean, Divakaran, Sanjay, Brown, Jenifer M, Bibbo, Courtney F, Barrett, Leanne, Hainer, Jon, Bay, Camden, Martell, Laurel, Kogelman, Laura, Triant, Virginia A, Chu, Jacqueline, Lin, Nina H, Melbourne, Kathleen, Sax, Paul E, Di Carli, Marcelo F

“…HIV infection and abacavir-containing antiretroviral regimens are associated with vascular endothelial dysfunction and increased cardiovascular risk. Positron…”
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Novel ELISA Protocol Links Pre-Existing SARS-CoV-2 Reactive Antibodies With Endemic Coronavirus Immunity and Age and Reveals Improved Serologic Identification of Acute COVID-19 via Multi-Parameter Detection by Yuen, Rachel R, Steiner, Dylan, Pihl, Riley M F, Chavez, Elizabeth, Olson, Alex, Smith, Erika L, Baird, Lillia A, Korkmaz, Filiz, Urick, Patricia, Sagar, Manish, Berrigan, Jacob L, Gummuluru, Suryaram, Corley, Ronald B, Quillen, Karen, Belkina, Anna C, Mostoslavsky, Gustavo, Rifkin, Ian R, Kataria, Yachana, Cappione, 3rd, Amedeo J, Gao, Wenda, Lin, Nina H, Bhadelia, Nahid, Snyder-Cappione, Jennifer E

“…The COVID-19 pandemic has drastically impacted work, economy, and way of life. Sensitive measurement of SARS-CoV-2 specific antibodies would provide new…”
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Age at Diagnosis of Heart Failure in United States Veterans With and Without HIV Infection by Erqou, Sebhat, Jiang, Lan, Choudhary, Gaurav, Lally, Michelle, Freiberg, Matthew, Lin, Nina H, Shireman, Theresa I, Rudolph, James L, Wu, Wen-Chih

“…Background Although HIV is associated with increased risk of heart failure (HF), it is not known if people living with HIV develop HF at a younger age compared…”
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Xenotropic Murine Leukemia Virus-Related Virus Prevalence in Patients with Chronic Fatigue Syndrome or Chronic Immunomodulatory Conditions by Henrich, Timothy J., Li, Jonathan Z., Felsenstein, Donna, Kotton, Camille N., Plenge, Robert, Pereyra, Florencia, Marty, Francisco M., Lin, Nina H., Grazioso, Paul, Crochiere, Danielle M., Eggers, Daniel, Kuritzkes, Daniel R., Tsibris, Athe M. N.

“…We investigated the prevalence of xenotropic murine leukemia virus-related virus (XMRV) among 293 participants seen at academic hospitals in Boston,…”
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Prevalence and Clinical Associations of CXCR4-Using HIV-1 Among Treatment-Naive Subtype C-Infected Women in Botswana by Lin, Nina H, Smeaton, Laura M, Giguel, Françoise, Novitsky, Vladimir, Moyo, Sikhulile, Mitchell, Rebecca M, Makhema, Joseph, Essex, Myron, Lockman, Shahin, Kuritzkes, Daniel R

“…HIV-1 coreceptor use was determined using a phenotypic assay in plasma samples from treatment-naive women infected with subtype C virus who had CD4 cell counts…”
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Integrase Inhibitor Use Associated with Weight Gain in Women and Incident Diabetes Mellitus by Asundi, Archana, Olson, Alex, Jiang, Wenqing, Varshney, Swati P, White, Laura F, Sagar, Manish, Lin, Nina H

“…Excessive weight gain associated with integrase strand transfer inhibitor (InSTI) antiretrovirals is an emerging issue; however, the metabolic consequences of…”
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Long-Term Reduction in Peripheral Blood HIV Type 1 Reservoirs Following Reduced-Intensity Conditioning Allogeneic Stem Cell Transplantation by Henrich, Timothy J., Hu, Zixin, Li, Jonathan Z., Sciaranghella, Gaia, Busch, Michael P., Keating, Sheila M., Gallien, Sebastien, Lin, Nina H., Giguel, Francoise F., Lavoie, Laura, Ho, Vincent T., Armand, Philippe, Soiffer, Robert J., Sagar, Manish, LaCasce, Ann S., Kuritzkes, Daniel R.

“…Background. The long-term impact of allogeneic hematopoietic stem cell transplantation (HSCT) on human immunodeficiency virus type 1 (HIV-1) reservoirs in…”
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Infectious Myelitis by Asundi, Archana, Cervantes-Arslanian, Anna M, Lin, Nina H, Barbosa, Felipe

“…Myelitis refers to inflammation of the spinal cord which can result in a spectrum of neurologic impairment. Infectious pathogens are an important etiologic…”
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Pandemic Response Requires Research Samples: A U.S. Safety-Net Hospital's Experience and Call for National Action by Ragan, Elizabeth J, McCallum, Caitryn, Marathe, Jai, Cole, Manisha, Hofman, Melissa, Henderson, Andrew J, Flack, Tyler, Miller, Nancy S, Burks, Eric J, Zhao, Grace Qing, Denis, Ridiane, Lin, Nina H, Jacobson, Karen R, Andry, Christopher D, Pelton, Stephen I, Duffy, Elizabeth R, Bhadelia, Nahid

“…Biorepositories provide a critical resource for gaining knowledge of emerging infectious diseases and offer a mechanism to rapidly respond to outbreaks; the…”
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Immunological and Neurometabolite Changes Associated With Switch From Efavirenz to an Integrase Inhibitor by Asundi, Archana, Robles, Yvonne, Starr, Tyler, Landay, Alan, Kinslow, Jennifer, Ladner, Joshua, White, Laura, Plank, Rebeca M, Melbourne, Kathleen, Weisholtz, Daniel, Bennett, Monica, Pan, Hong, Stern, Emily, Lin, Alexander, Kuritzkes, Daniel R, Lin, Nina H

“…BACKGROUND:The biological mechanisms by which efavirenz (EFV) causes central nervous system (CNS) effects are unclear. The objective of this pilot study was to…”
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Env sequence determinants in CXCR4-using human immunodeficiency virus type-1 subtype C by Lin, Nina H, Becerril, Carlos, Giguel, Francoise, Novitsky, Vladimir, Moyo, Sikhulile, Makhema, Joseph, Essex, Myron, Lockman, Shahin, Kuritzkes, Daniel R, Sagar, Manish

“…Abstract HIV-1 subtype C (HIV-1C) CXCR4-using virus is isolated infrequently and is poorly characterized. Understanding HIV-1C env characteristics has…”
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Elevated Levels of Microbial Translocation Markers and CCL2 Among Older HIV-1–Infected Men by Scully, Eileen, Lockhart, Ainsley, Huang, Lisa, Robles, Yvonne, Becerril, Carlos, Romero-Tejeda, Marisol, Albrecht, Mary A., Palmer, Christine D., Bosch, Ronald J, Altfeld, Marcus, Kuritzkes, Daniel R., Lin, Nina H.

“…The aging of the human immunodeficiency virus type 1 (HIV-1)–infected population obligates a focus on the interaction between aging, comorbid conditions, and…”
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Tropism testing in the clinical management of HIV-1 infection by Lin, Nina H, Kuritzkes, Daniel R

“…PURPOSE OF REVIEWA variety of methods are available to determine HIV-1 co-receptor usage, commonly referred to as viral tropism. This article reviews recent…”
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The design and validation of a novel phenotypic assay to determine HIV-1 coreceptor usage of clinical isolates by Lin, Nina H., Negusse, Daniel M., Beroukhim, Rameen, Giguel, Francoise, Lockman, Shahin, Essex, Myron, Kuritzkes, Daniel R.

“…A phenotypic assay to determine coreceptor usage of HIV-1 has been developed for rapid testing of clinical samples. The assay is based on the synthesis of…”
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Genome-Wide Association Study of Human Immunodeficiency Virus (HIV)-1 Coreceptor Usage in Treatment-Naive Patients from An AIDS Clinical Trials Group Study by Henrich, Timothy J, McLaren, Paul J, Rao, Suhas S P, Lin, Nina H, Hanhauser, Emily, Giguel, Francoise, Gulick, Roy M, Ribaudo, Heather, de Bakker, Paul I W, Kuritzkes, Daniel R

“…We conducted a genome-wide association study to explore whether common host genetic variants (>5% frequency) were associated with presence of virus able to use…”
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Inhibitory receptor signatures on gamma delta T cells predict ART-suppressed HIV infection, are synergistically altered by HIV and aging, and co-vary with inflammatory plasma analytes by Snyder-Cappione, Jennifer E., Belkina, Anna C., Starchenko, Alina, Drake, Katherine, Proctor, Elizabeth, Lauffenburger, Douglas A., Browning, Jeffrey L., Olson, Alex, Lin, Nina H.

“…Abstract Virologically suppressed HIV+ individuals have an increased risk and earlier onset of age-associated diseases such as cardiovascular atherosclerosis,…”
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946. Risk factors and Metabolic Implications of Integrase Inhibitor Associated Weight Gain by Asundi, Archana, Olson, Alex, Jiang, Wenqing, Patel, Swati, White, Laura F, Sagar, Manish, Lin, Nina H

“…Abstract Background Excessive weight gain associated with integrase strand transfer inhibitor (InSTI) antiretrovirals is an emerging issue in the current…”
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Intragenic proviral elements support transcription of defective HIV-1 proviruses by Kuniholm, Jeffrey, Armstrong, Elise, Bernabe, Brandy, Coote, Carolyn, Berenson, Anna, Patalano, Samantha D, Olson, Alex, He, Xianbao, Lin, Nina H, Fuxman Bass, Juan I, Henderson, Andrew J

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