Search Results - "Lin, Mei Chun"

Silencing of MUC20 suppresses the malignant character of pancreatic ductal adenocarcinoma cells through inhibition of the HGF/MET pathway by Chen, Syue-Ting, Kuo, Ting-Chun, Liao, Ying-Yu, Lin, Mei-Chun, Tien, Yu-Wen, Huang, Min-Chuan

“…Mucins are heavily glycosylated proteins that play critical roles in the pathogenesis of tumour malignancies. Pancreatic ductal adenocarcinoma (PDAC) is…”
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C1GALT1 predicts poor prognosis and is a potential therapeutic target in head and neck cancer by Lin, Mei-Chun, Chien, Pin-Hui, Wu, Hsin-Yi, Chen, Syue-Ting, Juan, Hsueh-Fen, Lou, Pei-Jen, Huang, Min-Chuan

“…Core 1 β1,3-galactosyltransferase (C1GALT1) controls the crucial step of GalNAc-type O-glycosylation and is overexpressed in various human malignancies…”
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Targeting tumor O‐glycosylation modulates cancer–immune‐cell crosstalk and enhances anti‐PD‐1 immunotherapy in head and neck cancer by Lin, Mei‐Chun, Chuang, Ya‐Ting, Wu, Hsin‐Yi, Hsu, Chia‐Lang, Lin, Neng‐Yu, Huang, Min‐Chuan, Lou, Pei‐Jen

“…Cells in the tumor microenvironment (TME) communicate via membrane‐bound and secreted proteins, which are mostly glycosylated. Altered glycomes of malignant…”
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Chemoprevention of oral cancer: A review and future perspectives by Liao, Yu‐Hao, Chou, Wei‐Yi, Chang, Chun‐Wei, Lin, Mei‐Chun, Wang, Cheng‐Ping, Lou, Pei‐Jen, Chen, Tseng‐Cheng

“…Background Oral cancer causes significant morbidity and mortality. Chemoprevention utilizes medication or natural compounds to reverse oral premalignant…”
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C1GALT1 is associated with poor survival and promotes soluble Ephrin A1-mediated cell migration through activation of EPHA2 in gastric cancer by Lee, Po-Chu, Chen, Syue-Ting, Kuo, Ting-Chun, Lin, Tzu-Chi, Lin, Mei-Chun, Huang, John, Hung, Ji-Shiang, Hsu, Chia-Lang, Juan, Hsueh-Fen, Lee, Po-Huang, Huang, Min-Chuan

“…C1GALT1 controls the crucial step of GalNAc-type O-glycosylation and is associated with both physiologic and pathologic conditions, including cancers. EPH…”
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Anti‐C1GALT1 Autoantibody Is a Novel Prognostic Biomarker for Patients With Head and Neck Cancer by Lin, Mei‐Chun, Huang, Min‐Chuan, Lou, Pei‐Jen

“…Objectives The objective of this study is to determine the value of the anti‐ glycoprotein‐N‐acetylgalactosamine 3‐beta‐galactosyltransferase 1 (C1GALT1)…”
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The G-quadruplex fluorescent probe 3,6-bis(1-methyl-2-vinyl-pyridinium) carbazole diiodide as a biosensor for human cancers by Tseng, Ting-Yuan, Chen, Wei-Wen, Chu, I-Te, Wang, Chiung-Lin, Chang, Cheng-Chung, Lin, Mei-Chun, Lou, Pei-Jen, Chang, Ta-Chau

“…Using time-gated fluorescence lifetime imaging microscopy, significantly more signals from 3,6-bis(1-methyl-2-vinyl-pyridinium) carbazole diiodide ( o -BMVC)…”
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Spindle Cell Carcinoma of the Head and Neck: Clinical Characteristics and Molecular Signatures by Lin, Mei‐Chun, Hsu, Chia‐Lang, Lai, Shih‐Fan, Huang, Yen‐Lin, Hsieh, Min‐Shu, Chen, Tseng‐Cheng, Chen, Chun‐Nan, Wang, Cheng‐Ping, Yang, Tsung‐Lin, Ko, Jenq‐Yuh, Tsai, Mong‐Hsun, Lou, Pei‐Jen

“…Objective/Hypothesis Spindle cell carcinoma of the head and neck (HNSpCC) is a rare variant of head and neck squamous cell carcinoma (HNSCC). This study…”
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Margin to depth of invasion ratio as an indicator for stratifying close margins in early-stage oral squamous cell carcinoma by Hung, Chun-Yang, Lee, Tung-Lin, Chang, Chun-Wei, Wang, Cheng-Ping, Lin, Mei-Chun, Lou, Pei-Jen, Chen, Tseng-Cheng

“…[Display omitted] •For early OSCC, MDR < 0.5 is an independent factor for disease-free survival.•Without adjuvant RT, clear or close margins (MDR ≥ 0.5) yield…”
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Truncation of GalNAc-type O-glycans Suppresses CD44-mediated Osteoclastogenesis and Bone Metastasis in Breast Cancer by Lin, Neng-Yu, Lee, Jian-Jr, Chen, Syue-Ting, Lin, Jung-An, Lin, Chia-Hsuan, Lin, Hsuan-Yu, Su, Yong-Han, Chen, Cheng-Chang, Lin, Mei-Chun, Kuo, Ching-Ying, Huang, Min-Chuan

“…The glycoprotein CD44 is a key regulator of malignant behaviors in breast cancer cells. To date, hyaluronic acid (HA)-CD44 signaling pathway has been widely…”
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Radiation‐induced sarcoma of head and neck: Clinical characteristics and molecular signatures by Liao, Yu‐Hao, Hsu, Chia‐Lang, Leu, Chih‐Yu, Lai, Shih‐Fan, Huang, Yen‐Lin, Hsieh, Min‐Shu, Chen, Tseng‐Cheng, Chen, Chun‐Nan, Wang, Cheng‐Ping, Yang, Tsung‐Lin, Tsai, Mong‐Hsun, Lin, Mei‐Chun, Lou, Pei‐Jen

“…Background Radiation‐induced sarcoma of the head and neck (RISHN) is a rare yet devastating potential complication of radiotherapy treatment. We aimed to…”
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GALNT2 enhances migration and invasion of oral squamous cell carcinoma by regulating EGFR glycosylation and activity by Lin, Mei-Chun, Huang, Miao-Juei, Liu, Chiung-Hui, Yang, Tsung-Lin, Huang, Min-Chuan

“…Summary Objectives Oral squamous cell carcinoma (OSCC) is one of the leading cancers worldwide. Aberrant glycosylation affects many cellular properties in…”
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When Cortical Bone Matrix Properties Are Indiscernible between Elderly Men with and without Type 2 Diabetes, Fracture Resistance Follows Suit by Wölfel, Eva M., Bartsch, Benjamin, Koldehoff, Jasmin, Fiedler, Imke A. K., Dragoun‐Kolibova, Sofie, Schmidt, Felix N., Krug, Johannes, Lin, Mei‐Chun, Püschel, Klaus, Ondruschka, Benjamin, Zimmermann, Elizabeth A., Jelitto, Hans, Schneider, Gerold, Gludovatz, Bernd, Busse, Björn

“…ABSTRACT Type 2 diabetes mellitus (T2DM) is a metabolic disease affecting bone tissue and leading to increased fracture risk in men and women, independent of…”
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Adequate surgical margins for oral cancer: A Taiwan cancer registry national database analysis by Lin, Mei-Chun, Leu, Yi-Shing, Chiang, Chun-Ju, Ko, Jenq-Yuh, Wang, Cheng-Ping, Yang, Tsung-Lin, Chen, Tseng-Cheng, Chen, Chun-Nan, Chen, Hsin-Lin, Liao, Chun-Ta, Tsai, Sen-Tien, Lin, Jin-Ching, Chu, Pen-Yuan, Tsai, Kuo-Yang, Tsai, Ming-Hsui, Huang, Huai-Cheng, Yang, Muh-Hwa, Wu, Yuan-Hua, Terng, Shyuang-Der, Chien, Chih-Yen, Liu, Tsang-Wu, Lee, Wen-Chung, Lou, Pei-Jen

“…•Adequate surgical margin for OSCC needs to be re-evaluated.•The study enrolled 15,654 patients with OSCC from the TCR database.•Advanced N stage and positive…”
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Production and Characterization of Durvillaea antarctica Enzyme Extract for Antioxidant and Anti-Metabolic Syndrome Effects by Ming-Kuei Shih, Chih-Yao Hou, Cheng-Di Dong, Anil Kumar Patel, Yung-Hsiang Tsai, Mei-Chun Lin, Zheng-Ying Xu, Pitchurajan Krishna Perumal, Chia-Hung Kuo, Chun-Yung Huang

“…In this study, three enzyme hydrolysate termed Dur-A, Dur-B, and Dur-C, were produced from Durvillaea antarctica biomass using viscozyme, cellulase, and…”
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A New TPACK Training Model for Tackling the Ongoing Challenges of COVID-19 by Cheng, Ping-Han, Molina, José, Lin, Mei-Chun, Liu, Hsiang-Hu, Chang, Chun-Yen

“…This study investigated the effects of integrating the “CloudClassRoom” (CCR) and the DEmo-CO-design/teach-feedback-DEbriefing (DECODE) model to improve…”
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Therapeutic vaccine targeting Epstein-Barr virus latent protein, LMP1, suppresses LMP1-expressing tumor growth and metastasis in vivo by Lin, Mei-Chun, Lin, Yong-Chong, Chen, Syue-Ting, Young, Tai-Horng, Lou, Pei-Jen

“…In endemic area, nasopharyngeal carcinoma (NPC) tumor cells harbor EBV latent infection and expresses viral antigens such as EBNA1, LMP1 and LMP2. In this…”
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Consensus and clinical recommendations for nutritional intervention for head and neck cancer patients undergoing chemoradiotherapy in Taiwan by Lin, Mei-Chun, Shueng, Pei-Wei, Chang, Wei-Kuo, Mu-Hsin Chang, Peter, Feng, Hsin-Chun, Yang, Muh-Hwa, Lou, Pei-Jen

“…•Significant weight loss before treatment predicts poor clinical outcomes.•PG-SGA is a common method to define the nutritional status.•Nutritional…”
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The forgotten body: history of sport and physical education for people with physical disabilities in Taiwan, 1945-1971 by Huang, Cheng-Hao, Howe, P. David, Lin, Mei-Chun, Jiang, Kai-xiao

“…The history of sport and physical education (PE) for people with physical disabilities is dominated by an ideological discourse that, through the process of…”
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Depth-dependent PD-L1 sampling of head and neck squamous cell carcinoma (HNSCC) – implications for PD-1/PD-L1 checkpoint inhibitor immunotherapy by Roy, Madhusudan, Lin, Jing-Tang, Mondal, Sohidul, Lin, Mei-Chun, Leu, Chih-Yu, Huang, Yen-Lin, Dong, Chen-Yuan, Lou, Pei-Jen

“…At present, PD-L1 scoring is the gold standard in evaluating a cancer patient's suitability for receiving PD-1/PD-L1 checkpoint inhibitor immunotherapy (CIT)…”
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