Search Results - "Lin, Lilong"
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TRIM25 promotes the cell survival and growth of hepatocellular carcinoma through targeting Keap1-Nrf2 pathway
Published in Nature communications (17-01-2020)“…Tumor cells often exhibit augmented capacity to maintain endoplasmic reticulum (ER) homeostasis under adverse conditions, yet the underlying mechanisms are not…”
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The tissue origin of human mesenchymal stem cells dictates their therapeutic efficacy on glucose and lipid metabolic disorders in type II diabetic mice
Published in Stem cell research & therapy (07-07-2021)“…Abstract Background The therapeutic efficacy of mesenchymal stem cells (MSCs) of different tissue origins on metabolic disorders can be varied in many ways but…”
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Treatment of acetaminophen-induced liver failure by blocking the death checkpoint protein TRAIL
Published in Biochimica et biophysica acta. Molecular basis of disease (01-01-2020)“…Acetaminophen (APAP) is one of the most commonly used drugs worldwide, and APAP-induced liver injury is the most frequent cause of acute liver failure in…”
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Network-Based Isoform Quantification with RNA-Seq Data for Cancer Transcriptome Analysis
Published in PLoS computational biology (01-12-2015)“…High-throughput mRNA sequencing (RNA-Seq) is widely used for transcript quantification of gene isoforms. Since RNA-Seq data alone is often not sufficient to…”
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Reprogramming somatic cells to cells with neuronal characteristics by defined medium both in vitro and in vivo
Published in Cell regeneration (2015)“…Currently, direct conversion from somatic cells to neurons requires virus-mediated delivery of at least one transcriptional factor or a combination of several…”
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Regulation of ROS in myeloid-derived suppressor cells through targeting fatty acid transport protein 2 enhanced anti-PD-L1 tumor immunotherapy
Published in Cellular immunology (01-04-2021)“…•FATP2 inhibition blocked ROS-mediated immunosuppressive function in MDSCs.•GM-CSF mediated FATP2 expression via activation of STAT3 signaling in MDSCs.•FATP2…”
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Metabolic switch and epithelial–mesenchymal transition cooperate to regulate pluripotency
Published in The EMBO journal (15-04-2020)“…Both metabolic switch from oxidative phosphorylation to glycolysis (OGS) and epithelial–mesenchymal transition (EMT) promote cellular reprogramming at early…”
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The homeobox transcription factor MSX2 partially mediates the effects of bone morphogenetic protein 4 (BMP4) on somatic cell reprogramming
Published in The Journal of biological chemistry (21-09-2018)“…Bone morphogenetic proteins (BMPs) induce mesenchymal–epithelial transition (MET) and enhance the generation of induced pluripotent stem cells (iPSCs)…”
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Passive DNA demethylation preferentially up-regulates pluripotency-related genes and facilitates the generation of induced pluripotent stem cells
Published in The Journal of biological chemistry (10-11-2017)“…A high proliferation rate has been observed to facilitate somatic cell reprogramming, but the pathways that connect proliferation and reprogramming have not…”
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Role of G protein-coupled receptor 1 in choriocarcinoma progression
Published in American Journal of Physiology: Cell Physiology (01-09-2019)“…Choriocarcinoma is characterized by malignant proliferation and transformation of trophoblasts and is currently treated with systemic chemotherapeutic agents…”
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Statin initiation and risk of incident kidney disease in patients with diabetes
Published in Canadian Medical Association journal (CMAJ) (29-05-2023)“…The role of statin therapy in the development of kidney disease in patients with type 2 diabetes mellitus (DM) remains uncertain. We aimed to determine the…”
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Variants of WNT7A and GPR124 are associated with hemorrhagic transformation following intravenous thrombolysis in ischemic stroke
Published in CNS neuroscience & therapeutics (01-01-2021)“…Aims The canonical Wnt signaling pathway plays an essential role in blood‐brain barrier integrity and intracerebral hemorrhage in preclinical stroke models…”
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Network-Based Isoform Quantification with RNA-Seq Data for Cancer Transcriptome Analysis: e1004465
Published in PLoS computational biology (01-12-2015)“…High-throughput mRNA sequencing (RNA-Seq) is widely used for transcript quantification of gene isoforms. Since RNA-Seq data alone is often not sufficient to…”
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Opioid doses required for pain management in lung cancer patients with different cholesterol levels: negative correlation between opioid doses and cholesterol levels
Published in Lipids in health and disease (08-03-2016)“…Pain management has been considered as significant contributor to broad quality-of-life improvement for cancer patients. Modulating serum cholesterol levels…”
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Sequential EMT-MET induces neuronal conversion through Sox2
Published in Cell discovery (30-05-2017)“…Direct neuronal conversion can be achieved with combinations of small-molecule compounds and growth factors. Here, by studying the first or induction phase of…”
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Correlation of lipoprotein(a) with clinical stability and severity of coronary artery lesions in patients with coronary artery disease
Published in Nan fang yi ke da xue xue bao = Journal of Southern Medical University (28-02-2019)“…To analyze the correlation of lipoprotein(a) [Lp(a)] with the clinical stability and severity of coronary artery stenosis in patients with coronary artery…”
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Network-based Isoform Quantification with RNA-Seq Data for Cancer Transcriptome Analysis
Published 15-09-2015“…High-throughput mRNA sequencing (RNA-Seq) is widely used for transcript quantification of gene isoforms. Since RNA-Seq data alone is often not sufficient to…”
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DEVELOPMENT OF AN AUTOMATIC WEIGHING PLATFORM FOR MONITORING BODYWEIGHT OF BROILER CHICKENS IN COMMERCIAL PRODUCTION
Published in Frontiers of Agricultural Science and Engineering (2023)“…● An automatic weighing system for monitoring bodyweight of broilers was developed. ● The new system was compared to the established live-bird sales weighing…”
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