Search Results - "Lin, Jusheng"
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miR-375 Inhibits Autophagy and Reduces Viability of Hepatocellular Carcinoma Cells Under Hypoxic Conditions
Published in Gastroenterology (New York, N.Y. 1943) (01-07-2012)“…Background & Aims Tumor cells survive hypoxic conditions by inducing autophagy. We investigated the roles of microRNAs (miRNAs) in regulating autophagy of…”
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High-Mobility Group Box 1 Promotes Hepatocellular Carcinoma Progression through miR-21-Mediated Matrix Metalloproteinase Activity
Published in Cancer research (Chicago, Ill.) (15-04-2015)“…Liver inflammation plays a critical role in hepatocellular carcinoma (HCC) etiology. Damage-associated molecular patterns (DAMP), such as high-mobility group…”
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3
Manipulation of autophagy by MIR375 generates antitumor effects in liver cancer
Published in Autophagy (01-12-2012)“…The exploration into the roles of autophagy in tumorigenesis, either as tumor suppressor or tumor promoter, has led to a great increase in the knowledge of…”
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Inhibition of miR-96 expression reduces cell proliferation and clonogenicity of HepG2 hepatoma cells
Published in Oncology reports (01-02-2013)“…microRNAs (miRNAs) are negative regulators of gene expression and can function as tumor suppressors or oncogenes. Several miRNAs are associated with the…”
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5
Correlations between ASCC3 Gene Polymorphisms and Chronic Hepatitis B in a Chinese Han Population
Published in PloS one (04-11-2015)“…We have previously identified 8 SNPs in Han Chinese HBV carriers that are associated with disease progression. Although not well studied, genetic factors may…”
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Associations of HLA-DP variants with hepatitis B virus infection in southern and northern Han Chinese populations: a multicenter case-control study
Published in PloS one (31-08-2011)“…Human leukocyte antigen DP (HLA-DP) locus has been reported to be associated with hepatitis B virus (HBV) infection in populations of Japan and Thailand. We…”
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Functional repair of p53 mutation in colorectal cancer cells using trans-splicing
Published in Oncotarget (10-02-2015)“…Mutation in the p53 gene is arguably the most frequent type of gene-specific alterations in human cancers. Current p53-based gene therapy contains the…”
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8
Hepatitis B Virus Infection Dampens CtIP Expression in Hepatoma Cell
Published in Journal of Cancer (01-01-2018)“…Hepatitis B virus (HBV) infection is a leading cause for hepatocellular carcinoma (HCC). Dysregulation of DNA double-strand break (DSB) repair may explain the…”
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TBX5 Variants are Associated with Susceptibility to and the Incidence of Liver Cirrhosis and Hepatocellular Carcinoma in the Chinese Population: A Multicenter and Follow-Up Study
Published in Infection and drug resistance (01-01-2023)“…Liver cirrhosis (LC) and hepatocellular carcinoma (HCC) are progressions affected by genetic predispositions, and persistent hepatitis B virus infection also…”
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10
Su1004 High Mobility Group Box-1 Can Increase miR-21 Expression in Hepatocellular Carcinoma Through STAT3 Signaling
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2013)Get full text
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11
β-2 Spectrin is involved in hepatocyte proliferation through the interaction of TGFβ/Smad and PI3K/AKT signalling
Published in Liver international (01-08-2012)“…Background Transforming growth factor (TGF) β signalling pathway plays a crucial role in liver regeneration following partial hepatectomy in mice. Evidence…”
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12
Activity identification of ribozyme and U1 snRNA chimeric ribozyme against TGFβ1 in cell-free system and in hepatic stellate cells
Published in Science in China. Series C, Life sciences (01-01-2006)“…Q93; Transforming growth factorβ1 (TGFβ1) is known to be intimately involved in many cellular processes. To explore the mechanism of TGFβ1 in these processes,…”
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13
Visualizing hepatitis B virus with biarsenical labelling in living cells
Published in Liver international (01-11-2014)“…Background Study on viruses has greatly benefited from visualization of viruses tagged with green fluorescent protein (GFP) in living cells. But GFP tag, as a…”
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14
Association of a single-nucleotide polymorphism within the miR-146a gene with susceptibility for acute-on-chronic hepatitis B liver failure
Published in Immunogenetics (New York) (01-04-2013)“…Excessive activation of innate immune response contributes to the pathogenesis of acute-on-chronic hepatitis B liver failure (ACLF-HBV). miR-146a was recently…”
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15
Embryonic liver fodrin involved in hepatic stellate cell activation and formation of regenerative nodule in liver cirrhosis
Published in Journal of cellular and molecular medicine (01-01-2012)“…Transforming growth factor (TGF) β1 plays a critical role in liver fibrosis. Previous studies demonstrated embryonic liver fodrin (ELF), a β‐spectrin was…”
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16
MCM3AP, a novel HBV integration site in hepatocellular carcinoma and its implication in hepatocarcinogenesis
Published in Journal of Huazhong University of Science and Technology. Medical sciences (01-08-2010)“…Summary A novel HBV integration site involved in hepatocarcinogenesis was investigated. The HBV DNA integration sites were detected by Alu-PCR in…”
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Suppressive effects of genomic imprinted gene PEG10 on hydrogen peroxide-induced apoptosis in L02 cells
Published in Journal of Huazhong University of Science and Technology. Medical sciences (01-12-2009)“…Summary The effects of PEG10 on hydrogen peroxide (H 2 O 2 )-induced apoptosis in human normal liver cell line L0 2 were investigated. The PEG10 gene was…”
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18
DNA double-strand breaks, potential targets for HBV integration
Published in Journal of Huazhong University of Science and Technology. Medical sciences (01-06-2010)“…Summary Hepatitis B virus (HBV)-induced hepatocellular carcinoma (HCC) is one of the most frequently occurring cancers. Hepadnaviral DNA integrations are…”
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19
β‐2 Spectrin is involved in hepatocyte proliferation through the interaction of TGF β/Smad and PI 3K/ AKT signalling
Published in Liver international (01-08-2012)“…Abstract Background Transforming growth factor ( TGF ) β signalling pathway plays a crucial role in liver regeneration following partial hepatectomy in mice…”
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20
Effect of ATRA on Contents of liver Retinoids, Oxidative Stress and Hepatic Injury in Rat Model of Extrahepatic Cholestasis
Published in Journal of Huazhong University of Science and Technology. Medical sciences (01-10-2007)“…The effects of all-trans-retinoic acid (ATRA) administration on the concentration of retinoids (RA and vitamin A) in liver, oxidative stress and the hepatic…”
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