Search Results - "Lin, Jim J.‐C."

Intercalated disc protein Xinβ is required for Hippo-YAP signaling in the heart by Guo, Haipeng, Lu, Yao Wei, Lin, Zhiqiang, Huang, Zhan-Peng, Liu, Jianming, Wang, Yi, Seok, Hee Young, Hu, Xiaoyun, Ma, Qing, Li, Kathryn, Kyselovic, Jan, Wang, Qingchuan, Lin, Jenny L.-C., Lin, Jim J.-C., Cowan, Douglas B., Naya, Francisco, Chen, Yuguo, Pu, William T., Wang, Da-Zhi

“…Intercalated discs (ICD), specific cell-to-cell contacts that connect adjacent cardiomyocytes, ensure mechanical and electrochemical coupling during…”
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Discontinuous thoracic venous cardiomyocytes and heart exhibit synchronized developmental switch of troponin isoforms by Kracklauer, Martin P., Feng, Han‐Zhong, Jiang, Wenrui, Lin, Jenny L.‐C., Lin, Jim J.‐C., Jin, Jian‐Ping

“…Cardiomyocyte‐like cells have been reported in thoracic veins of rodents and other mammals, but their differentiation state and relationship to the muscle mass…”
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Specification of actin filament function and molecular composition by tropomyosin isoforms by Bryce, Nicole S, Schevzov, Galina, Ferguson, Vicki, Percival, Justin M, Lin, Jim J-C, Matsumura, Fumio, Bamburg, James R, Jeffrey, Peter L, Hardeman, Edna C, Gunning, Peter, Weinberger, Ron P

“…The specific functions of greater than 40 vertebrate nonmuscle tropomyosins (Tms) are poorly understood. In this article we have tested the ability of two Tm…”
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Effect of Eradication of Helicobacter pylori on the Histology and Cellular Phenotype of Gastric Intestinal Metaplasia by Watari, Jiro, Das, Koushik K, Amenta, Peter S, Tanabe, Hiroki, Tanaka, Atsumi, Geng, Xin, Lin, Jim J.–C, Kohgo, Yutaka, Das, Kiron M

“…Background & Aims: Eradication of Helicobacter pylori appears to reduce gastric cancer incidence. We examined the effect of successful H pylori therapy on…”
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Divergent Regulation of the Sarcomere and the Cytoskeleton by Schevzov, Galina, Fath, Thomas, Vrhovski, Bernadette, Vlahovich, Nicole, Rajan, Sudarsan, Hook, Jeff, Joya, Josephine E., Lemckert, Frances, Puttur, Franz, Lin, Jim J.-C., Hardeman, Edna C., Wieczorek, David F., O'Neill, Geraldine M., Gunning, Peter W.

“…The existence of a feedback mechanism regulating the precise amounts of muscle structural proteins, such as actin and the actin-associated protein tropomyosin…”
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Specific features of neuronal size and shape are regulated by tropomyosin isoforms by Schevzov, Galina, Bryce, Nicole S, Almonte-Baldonado, Rowena, Joya, Josephine, Lin, Jim J-C, Hardeman, Edna, Weinberger, Ron, Gunning, Peter

“…Spatially distinct populations of microfilaments, characterized by different tropomyosin (Tm) isoforms, are present within a neuron. To investigate the impact…”
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Changes in protein profiles during course of experimental glomerulonephritis by Nazeer, Khurram, Janech, Michael G, Lin, Jim J-C, Ryan, Kevin J, Arthur, John M, Budisavljevic, Milos N

“…Better characterization of the molecular mechanisms underlying glomerular cell proliferation may improve our understanding of the pathogenesis of…”
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Autoimmunity against human tropomyosin isoforms in ulcerative colitis: Localization of specific human tropomyosin isoforms in the intestine and extraintestinal organs by Mirza, Zafar K., Sastri, Bhagyalakshmi, Lin, Jim J.‐C., Amenta, Peter S., Das, Kiron M.

“…Background: Tropomyosins (TMs) are microfilament cytoskeletal proteins, and 5 major human TM isoforms (hTM1‐5) are described. hTMs, particularly isoform 5…”
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Localization and function of Xinα in mouse skeletal muscle by Feng, Han-Zhong, Wang, Qinchuan, Reiter, Rebecca S, Lin, Jenny L-C, Lin, Jim J-C, Jin, J-P

“…The Xin repeat-containing proteins were originally found in the intercalated discs of cardiac muscle with implicated roles in cardiac development and function…”
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Isolation and sequencing of a novel tropomyosin isoform preferentially associated with colon cancer by Lin, Jenny L.–C., Geng, Xin, Bhattacharya, Sangeeta Das, Yu, Jae–Ran, Reiter, Rebecca S., Sastri, Bhagyalakshmi, Glazier, Kenneth D., Mirza, Zafar K., Wang, Kenneth K., Amenta, Peter S., Das, Kiron M., Lin, Jim J.–C.

“…Background & Aims: Nonmuscle human tropomyosin (hTM) isoforms have distinct functions and may play important roles in various disease processes. Methods: In an…”
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Loss of mXinα, an Intercalated Disk Protein, Results in Cardiac Hypertrophy and Cardiomyopathy with Conduction Defects by Choi, Sunju, Gustafson-Wagner, Elisabeth A, Wang, Qinchuan, Harlan, Shannon M, Sinn, Haley W, Lin, Jenny L.-C, Lin, Jim J.-C

“…Targeted deletion of mXinα results in cardiac hypertrophy and cardiomyopathy with conduction defects (Gustafson-Wagner, E., Sinn, H. W., Chen, Y.-L., Wang,…”
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h2-calponin Is Regulated by Mechanical Tension and Modifies the Function of Actin Cytoskeleton by Hossain, M. Moazzem, Crish, James F., Eckert, Richard L., Lin, Jim J.-C., Jin, Jian-Ping

“…Calponin is an extensively studied actin-binding protein, but its function is not well understood. Among three isoforms of calponin, h2-calponin is found in…”
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Tropomyosin and caldesmon regulate cytokinesis speed and membrane stability during cell division by Eppinga, Robbin D., Li, Yan, Lin, Jenny L.-C., Lin, Jim J.-C.

“…The contractile ring and the cell cortex generate force to divide the cell while maintaining symmetrical shape. This requires temporal and spatial regulation…”
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Sorting of a Nonmuscle Tropomyosin to a Novel Cytoskeletal Compartment in Skeletal Muscle Results in Muscular Dystrophy by Kee, Anthony J., Schevzov, Galina, Nair-Shalliker, Visalini, Robinson, C. Stephen, Vrhovski, Bernadette, Ghoddusi, Majid, Qiu, Min Ru, Jim J.-C. Lin, Weinberger, Ron, Gunning, Peter W., Hardeman, Edna C.

“…Tropomyosin (Tm) is a key component of the actin cytoskeleton and >40 isoforms have been described in mammals. In addition to the isoforms in the sarcomere, we…”
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Role of VEGF family members and receptors in coronary vessel formation by Tomanek, Robert J., Holifield, Jennifer S., Reiter, Rebecca S., Sandra, Alexander, Lin, Jim J.‐C.

“…The specific roles of vascular endothelial growth factor (VEGF) family members and their receptors (VEGFRs) in coronary vessel formation were studied. By using…”
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A Defect in the Kv Channel-Interacting Protein 2 (KChIP2) Gene Leads to a Complete Loss of Ito and Confers Susceptibility to Ventricular Tachycardia by Kuo, Hai-Chien, Cheng, Ching-Feng, Clark, Robert B., Lin, Jim J.-C., Lin, Jenny L.-C., Hoshijima, Masahiko, Nguyêñ-Trân, Vân T.B., Gu, Yusu, Ikeda, Yasuhiro, Chu, Po-Hsien, Ross, John, Giles, Wayne R., Chien, Kenneth R.

“…KChIP2, a gene encoding three auxiliary subunits of Kv4.2 and Kv4.3, is preferentially expressed in the adult heart, and its expression is downregulated in…”
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Requirement of reversible caldesmon phosphorylation at P21-activated kinase-responsive sites for lamellipodia extensions during cell migration by Eppinga, Robbin D., Li, Yan, Lin, Jenny L.-C., Mak, Alan S., Lin, Jim J.-C.

“…Caldesmon is believed to be one of the key regulators for actin dynamics and thereby cell polarity, membrane extension, and cell motility. We have shown…”
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Caldesmon mutant defective in Ca2+-calmodulin binding interferes with assembly of stress fibers and affects cell morphology, growth and motility by Li, Yan, Lin, Jenny L. C., Reiter, Rebecca S., Daniels, Karla, Soll, David R., Lin, Jim J. C.

“…Despite intensive in vitro studies, little is known about the regulation of caldesmon (CaD) by Ca2+-calmodulin (Ca2+-CaM) in vivo. To investigate this…”
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Localization of the novel Xin protein to the adherens junction complex in cardiac and skeletal muscle during development by Sinn, Haley W., Balsamo, Janne, Lilien, Jack, Lin, Jim J.‐C.

“…Previously, we demonstrated that chick embryos treated with antisense oligonucleotides against a striated muscle‐specific Xin exhibit abnormal cardiac…”
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1274 full-open reading frames of transcripts expressed in the developing mouse nervous system by Bonaldo, Maria F, Bair, Thomas B, Scheetz, Todd E, Snir, Einat, Akabogu, Ike, Bair, Jennifer L, Berger, Brian, Crouch, Keith, Davis, Aja, Eyestone, Mari E, Keppel, Catherine, Kucaba, Tamara A, Lebeck, Mark, Lin, Jenny L, de Melo, Anna I R, Rehmann, Joshua, Reiter, Rebecca S, Schaefer, Kelly, Smith, Christina, Tack, Dylan, Trout, Kurtis, Sheffield, Val C, Lin, Jim J-C, Casavant, Thomas L, Soares, Marcelo B

“…As part of the trans-National Institutes of Health (NIH) Mouse Brain Molecular Anatomy Project (BMAP), and in close coordination with the NIH Mammalian Gene…”
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