Search Results - "Lin, Jenny L. C."

Intercalated disc protein Xinβ is required for Hippo-YAP signaling in the heart by Guo, Haipeng, Lu, Yao Wei, Lin, Zhiqiang, Huang, Zhan-Peng, Liu, Jianming, Wang, Yi, Seok, Hee Young, Hu, Xiaoyun, Ma, Qing, Li, Kathryn, Kyselovic, Jan, Wang, Qingchuan, Lin, Jenny L.-C., Lin, Jim J.-C., Cowan, Douglas B., Naya, Francisco, Chen, Yuguo, Pu, William T., Wang, Da-Zhi

“…Intercalated discs (ICD), specific cell-to-cell contacts that connect adjacent cardiomyocytes, ensure mechanical and electrochemical coupling during…”
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Discontinuous thoracic venous cardiomyocytes and heart exhibit synchronized developmental switch of troponin isoforms by Kracklauer, Martin P., Feng, Han‐Zhong, Jiang, Wenrui, Lin, Jenny L.‐C., Lin, Jim J.‐C., Jin, Jian‐Ping

“…Cardiomyocyte‐like cells have been reported in thoracic veins of rodents and other mammals, but their differentiation state and relationship to the muscle mass…”
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Localization and function of Xinα in mouse skeletal muscle by Feng, Han-Zhong, Wang, Qinchuan, Reiter, Rebecca S, Lin, Jenny L-C, Lin, Jim J-C, Jin, J-P

“…The Xin repeat-containing proteins were originally found in the intercalated discs of cardiac muscle with implicated roles in cardiac development and function…”
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Isolation and sequencing of a novel tropomyosin isoform preferentially associated with colon cancer by Lin, Jenny L.–C., Geng, Xin, Bhattacharya, Sangeeta Das, Yu, Jae–Ran, Reiter, Rebecca S., Sastri, Bhagyalakshmi, Glazier, Kenneth D., Mirza, Zafar K., Wang, Kenneth K., Amenta, Peter S., Das, Kiron M., Lin, Jim J.–C.

“…Background & Aims: Nonmuscle human tropomyosin (hTM) isoforms have distinct functions and may play important roles in various disease processes. Methods: In an…”
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Loss of mXinα, an Intercalated Disk Protein, Results in Cardiac Hypertrophy and Cardiomyopathy with Conduction Defects by Choi, Sunju, Gustafson-Wagner, Elisabeth A, Wang, Qinchuan, Harlan, Shannon M, Sinn, Haley W, Lin, Jenny L.-C, Lin, Jim J.-C

“…Targeted deletion of mXinα results in cardiac hypertrophy and cardiomyopathy with conduction defects (Gustafson-Wagner, E., Sinn, H. W., Chen, Y.-L., Wang,…”
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Tropomyosin and caldesmon regulate cytokinesis speed and membrane stability during cell division by Eppinga, Robbin D., Li, Yan, Lin, Jenny L.-C., Lin, Jim J.-C.

“…The contractile ring and the cell cortex generate force to divide the cell while maintaining symmetrical shape. This requires temporal and spatial regulation…”
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A Defect in the Kv Channel-Interacting Protein 2 (KChIP2) Gene Leads to a Complete Loss of Ito and Confers Susceptibility to Ventricular Tachycardia by Kuo, Hai-Chien, Cheng, Ching-Feng, Clark, Robert B., Lin, Jim J.-C., Lin, Jenny L.-C., Hoshijima, Masahiko, Nguyêñ-Trân, Vân T.B., Gu, Yusu, Ikeda, Yasuhiro, Chu, Po-Hsien, Ross, John, Giles, Wayne R., Chien, Kenneth R.

“…KChIP2, a gene encoding three auxiliary subunits of Kv4.2 and Kv4.3, is preferentially expressed in the adult heart, and its expression is downregulated in…”
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Requirement of reversible caldesmon phosphorylation at P21-activated kinase-responsive sites for lamellipodia extensions during cell migration by Eppinga, Robbin D., Li, Yan, Lin, Jenny L.-C., Mak, Alan S., Lin, Jim J.-C.

“…Caldesmon is believed to be one of the key regulators for actin dynamics and thereby cell polarity, membrane extension, and cell motility. We have shown…”
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Caldesmon mutant defective in Ca2+-calmodulin binding interferes with assembly of stress fibers and affects cell morphology, growth and motility by Li, Yan, Lin, Jenny L. C., Reiter, Rebecca S., Daniels, Karla, Soll, David R., Lin, Jim J. C.

“…Despite intensive in vitro studies, little is known about the regulation of caldesmon (CaD) by Ca2+-calmodulin (Ca2+-CaM) in vivo. To investigate this…”
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Forced Expression of Chimeric Human Fibroblast Tropomyosin Mutants Affects Cytokinesis by Warren, Kerri S., Jenny L.-C. Lin, McDermott, Jeff P., Jim J.-C. Lin

“…Human fibroblasts generate at least eight tropomyosin (TM) isoforms (hTM1, hTM2, hTM3, hTM4, hTM5, hTM5a, hTM5b, and hTMsmα) from four distinct genes, and we…”
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Abstract 919: Intercalated Disk Protein Xin-beta is Required for the Hippo/YAP Signaling in the Heart by Guo, Haipeng, Lu, Yao Wei, Lin, Zhiqiang, Huang, Zhanpeng, Liu, Jianming, Hu, Xiaoyun, Wang, Yi, Fernandes, Tiago, Guo, Yuxuan, Lin, Jenny L.-C, Lin, Jim J.-C, Naya, Francisco, Pu, William T, Wang, Da-Zhi

“…Abstract only Cardiovascular diseases continue to be a leading cause of death and disability. Despite this alarming fact, there is lack of effectual treatment…”
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Overexpression of Human Fibroblast Caldesmon Fragment Containing Actin-, Ca++/Calmodulin-, and Tropomyosin-Binding Domains Stabilizes Endogenous Tropomyosin and Microfilaments by Warren, Kerri S., Jenny L.-C. Lin, Wamboldt, Dawn D., Jim J.-C. Lin

“…Fibroblast caldesmon is a protein postulated to participate in the modulation of the actin cytoskeleton and the regulation of actin-based motility. The cDNAs…”
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Localization and Function of Xinα in Mouse Skeletal Muscle by Feng, Hanzhong, Wang, Qinchuan, Lin, Jenny L.-C., Lin, Jim J.-C., Jin, Jian-Ping

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The Intercalated Disc Protein, mXinα, Is Capable of Interacting with β-Catenin and Bundling Actin Filaments by Choi, Sunju, Gustafson-Wagner, Elisabeth A., Wang, Qinchuan, Harlan, Shannon M., Sinn, Haley W., Lin, Jenny L.-C., Lin, Jim J.-C.

“…Targeted deletion of mXinα results in cardiac hypertrophy and cardiomyopathy with conduction defects (Gustafson-Wagner, E., Sinn, H. W., Chen, Y.-L., Wang,…”
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Caldesmon mutant defective in Ca(2+)-calmodulin binding interferes with assembly of stress fibers and affects cell morphology, growth and motility by Li, Yan, Lin, Jenny L C, Reiter, Rebecca S, Daniels, Karla, Soll, David R, Lin, Jim J C

“…Despite intensive in vitro studies, little is known about the regulation of caldesmon (CaD) by Ca(2+)-calmodulin (Ca(2+)-CaM) in vivo. To investigate this…”
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The intercalated disc protein, mXinα, is capable of interacting with β-catenin and bundling actin filaments. VOLUME 282 (2007) PAGES 36024-36036 by Choi, Sunju, Gustafson-Wagner, Elisabeth A., Wang, Qinchuan, Harlan, Shannon M., Sinn, Haley W., Lin, Jenny L.-C., Lin, Jim J.-C.

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The intercalated disk protein, mXinalpha, is capable of interacting with beta-catenin and bundling actin filaments [corrected] by Choi, Sunju, Gustafson-Wagner, Elisabeth A, Wang, Qinchuan, Harlan, Shannon M, Sinn, Haley W, Lin, Jenny L-C, Lin, Jim J-C

“…Targeted deletion of mXinalpha results in cardiac hypertrophy and cardiomyopathy with conduction defects (Gustafson-Wagner, E., Sinn, H. W., Chen, Y.-L., Wang,…”
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The Intercalated Disc Protein, mXinα, Is Capable of Interacting with β-Catenin and Bundling Actin Filaments by Sunju Choi, Elisabeth A. Gustafson-Wagner, Qinchuan Wang, Shannon M. Harlan, Haley W. Sinn, Jenny L.-C. Lin, Jim J.-C. Lin

“…Targeted deletion of mXin α results in cardiac hypertrophy and cardiomyopathy with conduction defects (Gustafson-Wagner, E., Sinn, H. W., Chen, Y.-L., Wang,…”
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Loss of mXinalpha, an intercalated disk protein, results in cardiac hypertrophy and cardiomyopathy with conduction defects by Gustafson-Wagner, Elisabeth A, Sinn, Haley W, Chen, Yen-Lin, Wang, Da-Zhi, Reiter, Rebecca S, Lin, Jenny L-C, Yang, Baoli, Williamson, Roger A, Chen, Ju, Lin, Cheng-I, Lin, Jim J-C

“…The intercalated disk protein Xin was originally discovered in chicken striated muscle and implicated in cardiac morphogenesis. In the mouse, there are two…”
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Overexpression of microfilament-stabilizing human caldesmon fragment, CaD39, affects cell attachment, spreading, and cytokinesis by Warren, Kerri S., Shutt, Damon C., McDermott, Jeff P., Lin, Jenny L.-C., Soll, David R., Lin, Jim J.-C.

“…Previous studies have demonstrated that overexpression of the carboxyl‐terminal fragment, CaD39, of human fibroblast caldesmon in Chinese hamster ovary cells…”
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